- p53-mediated HIV-1 Tat Suppression is Likely to be Assaciated with duble-stranded RNA-dependent Protein Kinase, PKR
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Kim JW, Byun HS, Bae YS
- KMID: 1544230
- J Korean Soc Virol.
- 1999 Dec;29(4):235-245.
No abstract available. -
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- PKR as a Regulator of Inflammasome Activation
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Manzoor Z, Koh YS
- KMID: 2168684
- J Bacteriol Virol.
- 2013 Jun;43(2):145-147.
- doi: 10.4167/jbv.2013.43.2.145
Detection of pathogen by pattern recognition receptors leads to activation of inflammasome which plays a crucial role in immune system. The inflammasome regulates the release of cytokines, such as interleukin... -
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- Human Leptin Protein Induces Proliferation of A549 Cells via Inhibition of PKR-Like ER Kinase and Activating Transcription Factor-6 Mediated Apoptosis
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Lai Q, Sun Y
- KMID: 1798137
- Yonsei Med J.
- 2013 Nov;54(6):1407-1415.
- doi: 10.3349/ymj.2013.54.6.1407
PURPOSE: To investigate the anti-apoptotic mechanism of leptin in non-small cell lung cancer. MATERIALS AND METHODS: The influences of leptin on apoptosis were investigated, analyzing the mechanism that triggers growth of... -
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- Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon
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Boo KH, Yang JS
- KMID: 1779600
- Yonsei Med J.
- 2010 Jan;51(1):9-17.
- doi: 10.3349/ymj.2010.51.1.9
Intrinsic cellular defenses are non-specific antiviral activities by recognizing pathogen-associated molecular patterns (PAMPs). Toll-like receptors (TLRs), one of the pathogen recognize receptor (PRR), sense various microbial ligands. Especially, TLR2, TLR3,... -
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