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Efficacy of Vancomycin-beta-lactam Combinations Against Heterogeneously Vancomycin-Resistant Staphylococcus aureus (hetero-VRSA)

Kim YS, Kiem S, Yun HJ, Jung SI, Oh WS, Kim SW, Peck KR, Lee NY, Song JH

There have been conflicting data about the interactions between vancomycin and beta-lactam agents against Staphylococcus aureus strains with heterogeneous resistance to vancomycin. We evaluated the efficacy of these combinations against...
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Emergence of beta-Lactam-Dependent Bacillus cereus associated with Prolonged Treatment with Cefepime in a Neutropenic Patient

Ko SY, Chung HJ, Sung HS, Kim MN

Antibiotic dependence in clinical isolates has been reported, albeit rarely, such as vancomycindependent enterococcus and beta-lactam-dependent Staphylococcus saprophyticus. We report herein a clinical isolate of beta-lactam-dependent Bacillus cereus. A 16-yr-old...
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Mechanism of beta-lactam Resistance in Gram-negative Rods Isolated from Surgical Site Infection

Shin HS, Kim YS, Cho DT

  • KMID: 1550833
  • Korean J Infect Dis.
  • 1999 Oct;31(5):390-401.
BACKGROUND: There have been few studies about the kinds of species causing surgical site infections and their resistance pattern in Korea. An increase of extended-spectrum beta-lactamase (ESBL) producing strains is...
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Isolation of Klebsiella Oxytoca Clinical Isolate Producing AmpC beta-lactamase, DHA-1

Song W, Kim JS, Kim HS, Lee TJ, Park MJ, Park IH, Lee KM

  • KMID: 1892726
  • Korean J Clin Microbiol.
  • 2004 Sep;7(2):124-129.
BACKGROUND: Klebsiella oxytoca strain exhibiting an unusual inducible beta-lactam resistance phenotype was isolated from a wound specimen of a patient at a university hospital in August 2002. The isolate was...
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Detection of Extended-spectrum beta-lactamase in Klebsiella pneumoniae

Lee SY, Lee SH, Pai CH

  • KMID: 2146209
  • Korean J Clin Pathol.
  • 1997 Dec;17(6):1076-1088.
BACKGROUNDS : Extended spectrum beta-lactamases (ESBL) are plasmid-mediated enzymes that confer broad-spectrum resistance to aztreonam, most penicillins, and cephalosporins including ceftazidime, cefotaxime and ceftriaxone. But with most routine susceptibility tests,...
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Prevalence of Extended-Spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae from Daejeon

Ko CS, Sung JY, Koo SH, Kwon GC, Shin SY, Park JW

BACKGROUND: Extended-spectrum beta-lactamases (ESBLs) are cephalosporinases that confer resistance to a wide variety of oxyimino cephalosporins and create serious therapeutic problems. Although ESBLs have been reported with increasing frequency...
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The Characteristics of Metallo-beta-Lactamase-Producing Gram-Negative Bacilli Isolated from Sputum and Urine: A Single Center Experience in Korea

Chin BS, Han SH, Choi SH, Lee HS, Jeong SJ, Choi HK, Choi JY, Song YG, Kim CK, Yong D, Lee K, Kim JM

Metallo-beta-lactamase (MBL) production usually results in high-level resistance to most beta-lactams, and a rapid spread of MBL producing major gram-negative pathogens is a matter of particular concern worldwide. However, clinical...
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Reverse vaccinology approach for the identification and characterization of outer membrane proteins of Shigella flexneri as potential cellular- and antibody-dependent vaccine candidates

Leow CY, Kazi A, Hisyam Ismail CMK, Chuah C, Lim BH, Leow CH, Banga Singh KK

PURPOSE: In the developing world, bacillary dysentery is one of the most common communicable diarrheal infections. There are approximately 169 million cases of shigellosis reported worldwide. The disease is transmitted...
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