- Occupational asthma induced by beat-galactosidase
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Kim MK
- KMID: 2168575
- Allergy Asthma Respir Dis.
- 2014 Mar;2(1):75-77.
- doi: 10.4168/aard.2014.2.1.75
Galactosidase is generated from Aspergillus oryzae, which is widely used for antidiarrhea medicine to infants. Antibiotics and digestives were reported as a causative allergen inducing occupational asthma. Galatosidase-induced occupational asthma... -
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- Urinary beta-Galactosidase Activity as an Early Indicator of Renal Dysfunction in Workers Exposed to Mercury Vapor
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Oh YH, Kim KJ, Chon BC, Park JT
- KMID: 2141615
- Korean J Occup Environ Med.
- 1995 Feb;7(1):128-138.
The objective of this study was to evaluate the relationship between beta-galactosidase activity in urine, in serum and urinary N-acetyl-beta-glucosarminidase activity as an early indicator of renal effect and mercurT... -
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- Transfection of SV 40 Large T Antigen into Corneal Endothelial Cells
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Cho KS, Fleming TP, Lee EH, Joo CK
- KMID: 2205471
- J Korean Ophthalmol Soc.
- 1999 Mar;40(3):676-682.
The coeneal endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency. However, corneal endothelial cells are incapable of significant proliferation in vivo. As we age, the... -
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- Heterologous Regulation of BCG hsp65 Promoter by M. leprae 18 kDa Transcription Repression Responsive Element
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Kim HB, You JC
- KMID: 2053075
- Genomics Inform.
- 2003 Dec;1(2):113-118.
Among a number of antigens characterized in M. leprae, an etiological agent of Leprosy, the 18 kDa antigen, is unique to M. leprae. We have previously determined a sequence specific... -
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- A Galactosialidosis Mimicking GM1-gangliosidosis Type I
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Im SJ, Nam SO
- KMID: 2329332
- J Korean Child Neurol Soc.
- 2005 Nov;13(2):288-293.
Galactosialidosis is a lysosomal storage disease associated with a combined deficiency of beta-galactosidase and alpha-neuraminidase, secondary to a defect of another lysosomal protective protein. It is a neurodegenerative disorder clinically... -
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- Urinary enzyme levels after ESWL for renal stone
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Choi HS, Choi SH
- KMID: 2036805
- Korean J Urol.
- 1993 Feb;34(1):103-108.
ESWL is a safe and effective treatment for renal calculi. However, on destruction of the stone, the pressure of shock waves produces renal microdamage. Urinary enzyme testing has been used... -
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- Measurement of Replicative Senescence in Long Term Cultured Human Keratinocytes
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Yoon KH, Yin L, Song IH, Sung HK, Kim JY, Park JH, Lee YC, Sung EG
- KMID: 2224526
- Korean J Anat.
- 2000 Dec;33(6):643-650.
The keratinocyte culture has been used for the reconstruction of artificial skin or as in vitro skin model. For these purpose, keratinocytes should be cultured for long time (usually 10... -
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- Progressive Myoclonus Epilepsy Associated with Macular Cherry-Red Spots
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Kang KS, Yun CH, Lee SK
- KMID: 2343046
- J Korean Neurol Assoc.
- 2003 Apr;21(2):204-206.
Myoclonus, generalized epilepsy, and progressive neurological decline characterize progressive myoclonus epilepsy. A 25-year-old woman was admitted for the evaluation of seizure, progressive myoclonus and ataxic gait. Her symptoms had developed... -
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- Genetic Safety Study of Chlorpromazine
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Kim HG, Shon YH, Lee KH, Yoon TH, Nam KS
- KMID: 2340464
- J Korean Neuropsychiatr Assoc.
- 2000 May;39(3):629-637.
OBJECT: The aim of this study is to determine whether exposure to chlorpromazine causes mutagenicity and genetic disorders. METHOD: Ames (Salmonella typhimurium) test and Rec assay (Bacillus subtilis) were used as... -
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- Prolonged expression of senescence markers in mice exposed to gamma-irradiation
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Seol MA, Jung U, Eom HS, Kim SH, Park HR, Jo SK
- KMID: 2391990
- J Vet Sci.
- 2012 Dec;13(4):331-338.
Although ionizing radiation is known to induce cellular senescence in vitro and in vivo, its long-term in vivo effects are not well defined. In this study, we examined the prolonged... -
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- Inhibition of TGF-beta by Gene Delivery does not Alter the Neointima Area, but Enhances Inflammation in In-Stent Stenosis of Pig Coronary Arteries
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Chung IM
- KMID: 2227174
- Korean Circ J.
- 2004 Nov;34(11):1022-1032.
- doi: 10.4070/kcj.2004.34.11.1022
BACKGROUND: We have shown that extracellular matrix (ECM) rather than cell proliferation contributes to in-stent restenosis. Transforming growth factor-beta (TGF-beta), a positive regulator of ECM deposition by vascular cells, may... -
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- The Role of Cellular Senescence in the Gastrointestinal Mucosa
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Penfield J, Anderson M, Lutzke L, Wang KK
- KMID: 1431336
- Gut Liver.
- 2013 May;7(3):270-277.
- doi: 10.5009/gnl.2013.7.3.270
Cellular senescence is a biologically irreversible state of cell-growth arrest that occurs following either a replicative or an oncogenic stimulus. This phenomenon occurs as a response to the presence of... -
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- A Case of Krabbe Disease Confirmed by Identification of Mutations in the Galactocerbroside beta-galactosidase Gene (GALC)
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Nam KS, Rhu SH, Sung YH, Oh MS, Jeong HW, Lee BC, Lee KH, Min KS, Han SH, Ki CS, Kim JW
- KMID: 1585786
- J Korean Neurol Assoc.
- 2004 Apr;22(2):167-171.
Krabbe disease is an autosomal recessive disorder involving white matter caused by deficient activity of the lysosomal galactocerebrosidase (GALC). A typical infantile-onset patient shows developmental regression, spasticity, and seizure before... -
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- Radiation Induced Senescence-like Changes of Endothelial Cells and Blood-brain Barrier Disruption
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Bang JS, Kwon OK, Oh CW
- KMID: 1470183
- Korean J Cerebrovasc Surg.
- 2009 Mar;11(1):12-18.
OBJECTIVES: This study was performed to evaluate the relationship between radiation induced senescence-like changes of endothelial cells and blood-brain barrier disruption. MATERIALS AND METHODS: Radiation of 15 Gy was applied... -
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- Neural Pathway Innervating Epididymis of Rats by Pseudorabies virus (PRV-Ba-Gal) and WGA-HRP
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Lee CH, Ko BM, Lee BH, Chung OB
- KMID: 1558429
- Korean J Anat.
- 2001 Apr;34(2):141-154.
This experimental studies was to investigate the location of PNS and CNS labeled neurons following injection of 2% WGA-HRP and pseudorabies virus (PRV), beta-galactosidase inserted Bartha strain, into the epididymis... -
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- Blockade of TGF-beta by Catheter-based Gene Transfer of a Soluble TGF-beta Type II Receptor Inhibits Neointima Formed after Stenting
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Chung IM, Choi DH, Min PK, Chung KY
- KMID: 1938855
- Korean Circ J.
- 2004 Jan;34(1):59-68.
- doi: 10.4070/kcj.2004.34.1.59
BACKGROUND: Enhanced extracellular matrix (ECM) accumulation is an important finding in coronary stent restenotic tissue, in which TGF-beta, implicated in ECM formation, is expressed abundantly. We assessed the hypothesis that... -
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- Enhanced bone morphogenic protein adenoviral gene delivery to bone marrow stromal cells using magnetic nanoparticle
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Lee JT, Jung JW, Choi JY, Kwon TG
- KMID: 1430478
- J Korean Assoc Oral Maxillofac Surg.
- 2013 Jun;39(3):112-119.
- doi: 10.5125/jkaoms.2013.39.3.112
OBJECTIVES: This study investigated the question of whether adenoviral magnetofection can be a suitable method for increasing the efficacy of gene delivery into bone marrow stromal cell (BMSC) and for... -
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- Gene Therapy of Brain Tumors:Effects of Adenovirus-mediated Wild Type p53 Gene Transfer in Human Glioma Cells
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Hong YK, Yung WK
- KMID: 2018899
- J Korean Neurosurg Soc.
- 1996 Aug;25(8):1561-1567.
The p53 tumor suppressor gene is one of the genes with greatest therapeutic potential for cancer treatment and its growth inhibitory mechanism is thought to be mediated through the activation... -
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- A simple human immunodeficiency virus vector system for selective infection of CD4(+) cells and inducible expression of foreign genes
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Kim YS
- KMID: 2045605
- Exp Mol Med.
- 1997 Jun;29(2):103-110.
The alteration of T lymphocyte functions as a consequence of human immunodeficiency virus (HIV) infection is a potential target for the genetic treatment of the acquired immunodeficiency syndrome (AIDS). One... -
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- Non-Surgical Gene Transfer to Rabbit Renal Glomeruli via Percutaneous Arterial Catheterization
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Park BH, Hwang TH, Kim SE, Kim KH, Kong GS, Jun HS, Jeong JS, Rha SH
- KMID: 2079421
- Korean J Nephrol.
- 2005 Jan;24(1):19-25.
BACKGROUND: Transfer of foreign genes to the renal glomerular cells is an important step for the gene therapy of renal diseases in which the primary pathology is confined to the... -
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