- Immunohistochemical Analysis of BAD Protein Expression in Gastric Carcinomas
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Yoo NJ, Lee JW, Park WS, Lee JY, Lee SH
- KMID: 2372719
- J Korean Gastric Cancer Assoc.
- 2003 Jun;3(2):75-79.
PURPOSE: Evidence exists that dysregulation of apoptosis is involved in the pathogenesis of cancer development. The Bcl-XL/Bcl-2-associated death promoter (BAD), a member of the Bcl-2 family, is a critical regulatory... -
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- Mechanism of FHIT-Induced Apoptosis in Lung Cancer Cell Lines
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Yoo JS, Kim CH
- KMID: 2132973
- Tuberc Respir Dis.
- 2004 May;56(5):450-464.
- doi: 10.4046/trd.2004.56.5.450
BACKGROUND: The FHIT (fragile histidine triad) gene is a frequent target of deletions associated with abnormal RNA and protein expression in lung cancer. Previous studies have shown FHIT gene transfer... -
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- A Experimental Study of PTEN (Phosphatase and Tensin) Role in Mesothelioma
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Lee SK, Kim KC
- KMID: 1987631
- Korean J Thorac Cardiovasc Surg.
- 2003 Nov;36(11):852-857.
BACKGROUND: Conventional treatment for mesothelioma is largely ineffective. We evaluated the novel approach of adenoviral gene transfection of PTEN gene in mesothelioma cancer cell lines, inflammatory and epithelial subtype, which... -
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- Capsaicin-Induced Apoptosis of FaDu Human Pharyngeal Squamous Carcinoma Cells
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Le TD, Jin DC, Rho SR, Kim MS, Yu R, Yoo H
- KMID: 1716886
- Yonsei Med J.
- 2012 Jul;53(4):834-841.
- doi: 10.3349/ymj.2012.53.4.834
PURPOSE: To investigate the anti-tumor effect of capsaicin on human pharyngeal squamous carcinoma cells (FaDu). MATERIALS AND METHODS: The expression of apoptosis/cell cycle-related proteins (or genes) was examined by reverse transcriptase-polymerase... -
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- Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex
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Jeon WJ, Kim SH, Seo MS, Kim Y, Kang UG, Juhnn YS, Kim YS
- KMID: 1094123
- Exp Mol Med.
- 2008 Aug;40(4):435-444.
- doi: 10.3858/emm.2008.40.4.435
Repeated electroconvulsive seizure (ECS), a model for electroconvulsive therapy (ECT), exerts neuroprotective and proliferative effects in the brain. This trophic action of ECS requires inhibition of apoptotic activity, in addition... -
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- Growth Inhibition of Hepatocellular Carcinoma Huh7 Cells by Lactobacillus casei Extract
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Han DJ, Kim JB, Park SY, Yang MG, Kim H
- KMID: 1793166
- Yonsei Med J.
- 2013 Sep;54(5):1186-1193.
- doi: 10.3349/ymj.2013.54.5.1186
PURPOSE: Lactobacillus casei (L. casei) is known to exert anti-proliferation effects on many types of cancer cells. However, the effect of L. casei on liver cancer has not been reported.... -
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- zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells
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Yee SB, Baek SJ, Park HT, Jeong SH, Jeong JH, Kim TH, Kim JM, Jeong BK, Park BS, Kwon TK, Yoon I, Yoo YH
- KMID: 1115941
- Exp Mol Med.
- 2006 Dec;38(6):634-642.
In a preliminary study, we found that benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone (zVAD- fmk), unlike Boc-aspartyl(OMe)-fluoromethylketone (BocD-fmk), at usual dosage could not prevent genistein-induced apoptosis of p815 mastocytoma cells. This study was undertaken to... -
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- Transactivation of bad by vorinostat-induced acetylated p53 enhances doxorubicin-induced cytotoxicity in cervical cancer cells
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Lee SJ, Hwang SO, Noh EJ, Kim DU, Nam M, Kim JH, Nam JH, Hoe KL
- KMID: 2155341
- Exp Mol Med.
- 2014 Feb;46(2):e76.
- doi: 10.1038/emm.2013.149
Vorinostat (VOR) has been reported to enhance the cytotoxic effects of doxorubicin (DOX) with fewer side effects because of the lower DOX dosage in breast cancer cells. In this study,... -
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