- DNA Vaccines Encoding Toxoplasma gondii Cathepsin C 1 Induce Protection against Toxoplasmosis in Mice
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Han Y, Zhou A, Lu G, Zhao G, Sha W, Wang L, Guo J, Zhou J, Zhou H, Cong H, He S
- KMID: 2395754
- Korean J Parasitol.
- 2017 Oct;55(5):505-512.
- doi: 10.3347/kjp.2017.55.5.505
Toxoplasma gondii cathepsin C proteases (TgCPC1, 2, and 3) are important for the growth and survival of T. gondii. In the present study, B-cell and T-cell epitopes of TgCPC1 were... -
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- Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma
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Ye YH, Xin HY, Li JL, Li N, Pan SY, Chen L, Pan JY, Hu ZQ, Wang PC, Luo CB, Sun RQ, Fan J, Zhou J, Zhou ZJ, Zhou SL
- KMID: 2560093
- Clin Mol Hepatol.
- 2024 Oct;30(4):914-928.
- doi: 10.3350/cmh.2024.0296
Background: Intrahepatic cholangiocarcinoma (ICC) is a highly desmoplastic tumor with poor prognosis even after curative resection. We investigated the associations between the composition of the ICC stroma and immune cell... -
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- Effect of FTY-720 on Pulmonary Fibrosis in Mice via the TGF-β1 Signaling Pathway and Autophagy
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Jin Y, Liu W, Gao G, Song Y, Liu H, Li L, Zhou J, Yan G, Cui H
- KMID: 2544066
- Biomol Ther.
- 2023 Jul;31(4):434-445.
- doi: 10.4062/biomolther.2022.123
We investigated whether FTY-720 might have an effect on bleomycin-induced pulmonary fibrosis through inhibiting TGF-β1 pathway, and up-regulating autophagy. The pulmonary fibrosis was induced by bleomycin. FTY-720 (1 mg/kg) drug... -
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- Identification of a mimotope of an infectious bronchitis virus S1 protein
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Zhou J, Li J, Li Y, Liu H, Qi Y, Wang A
- KMID: 2518811
- J Vet Sci.
- 2021 Jul;22(4):e49.
- doi: 10.4142/jvs.2021.22.e49
The S1 protein of the infectious bronchitis virus (IBV) is a major structural protein that induces the production of the virus-neutralization antibodies. The monoclonal antibody against the IBV M41 S1... -
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- Macrophage ATG16L1 expression suppresses metabolic dysfunction-associated steatohepatitis progression by promoting lipophagy
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Wang Q, Bu Q, Xu Z, Liang Y, Zhou J, Pan Y, Zhou H, Lu L
- KMID: 2557399
- Clin Mol Hepatol.
- 2024 Jul;30(3):515-538.
- doi: 10.3350/cmh.2024.0107
Background/Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is an unmet clinical challenge due to the rapid increased occurrence but lacking approved drugs. Autophagy-related protein 16-like 1 (ATG16L1) plays an important role in... -
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- Evaluation of Molecular Residual Disease by a Fixed Panel in Resectable Colorectal Cancer
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Yang J, Yu C, Li H, Peng D, Zhou Q, Yao J, Lv J, Fang S, Shi J, Wei Y, Wang G, Cai S, Zhang Z, Zhang Z, Zhou J
- KMID: 2560252
- Cancer Res Treat.
- 2024 Oct;56(4):1183-1196.
- doi: 10.4143/crt.2023.1371
Purpose Molecular residual disease (MRD) is a promising biomarker in colorectal cancer (CRC) for prognosis and guiding treatment, while the whole-exome sequencing (WES) based tumor-informed assay is standard for evaluating... -
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- The Role of Intestinal Fungi and Its Metabolites in Chronic Liver Diseases
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You N, Zhuo L, Zhou J, Song Y, Shi J
- KMID: 2500532
- Gut Liver.
- 2020 May;14(3):291-296.
- doi: 10.5009/gnl18579
Current studies have confirmed that liver diseases are closely related to intestinal microorganisms; however, those studies have mainly concentrated on bacteria. Although the proportion of intestinal microorganisms accounted for by... -
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- Biomaterials-based Approaches for Cardiac Regeneration
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Vasu S, Zhou J, Chen J, Johnston PV, Kim DH
- KMID: 2523160
- Korean Circ J.
- 2021 Dec;51(12):943-960.
- doi: 10.4070/kcj.2021.0291
The limited ability of cardiomyocytes to proliferate is a major cause of mortality and morbidity in cardiovascular diseases. There exist therapies for cardiac regeneration that are cell-based as well as... -
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- Characteristics Detected on Computed Tomography Angiography Predict Coronary Artery Plaque Progression in Non-Culprit Lesions
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Tan Y, Zhou J, Zhou Y, Yang X, Yang J, Chen Y
- KMID: 2427304
- Korean J Radiol.
- 2017 Jun;18(3):487-497.
- doi: 10.3348/kjr.2017.18.3.487
OBJECTIVE: This study sought to determine whether variables detected on coronary computed tomography angiography (CCTA) would predict plaque progression in non-culprit lesions (NCL). MATERIALS AND METHODS: In this single-center trial, we... -
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- Glial and Vascular Cell Regulation of the Blood-Brain Barrier in Diabetes
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Li X, Cai Y, Zhang Z, Zhou J
- KMID: 2527716
- Diabetes Metab J.
- 2022 Mar;46(2):222-238.
- doi: 10.4093/dmj.2021.0146
As a structural barrier, the blood-brain barrier (BBB) is located at the interface between the brain parenchyma and blood, and modulates communication between the brain and blood microenvironment to maintain... -
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- Zoster sine herpete: a review
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Zhou J, Li J, Ma L, Cao S
- KMID: 2504066
- Korean J Pain.
- 2020 Jul;33(3):208-215.
- doi: 10.3344/kjp.2020.33.3.208
Zoster sine herpete (ZSH) is one of the atypical clinical manifestations of herpes zoster (HZ), which stems from infection and reactivation of the varicella-zoster virus (VZV) in the cranial nerve,... -
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- Hospitalization Due to Asthma Exacerbation: A China Asthma Research Network (CARN) Retrospective Study in 29 Provinces Across Mainland China
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Lin J, Xing B, Tang H, Yang L, Yuan Y, Gu Y, Chen P, Liu X, Zhang J, Liu H, Wang C, Zhou W, Sun D, Chen Y, Chen Z, Huang M, Lin Q, Hu C, Yang X, Huo J, Ye X, Zhou X, Jiang P, Zhang W, Huang Y, Dai L, Liu R, Cai S, Xu J, Zhou J, on behalf of China Asthma Research Network
- KMID: 2471231
- Allergy Asthma Immunol Res.
- 2020 May;12(3):485-495.
- doi: 10.4168/aair.2020.12.3.485
PURPOSE: Details of patients hospitalized for asthma exacerbation in mainland China are lacking. To improve disease control and reduce economic burden, a large sample survey among this patient population is... -
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- Effects of Illness Perception and Health Beliefs on the Quality of Life of Breast Cancer Patients in the Yanbian Area of China
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Zheng F, Lee O, Zhou J, Li C
- KMID: 2459439
- Asian Oncol Nurs.
- 2019 Sep;19(3):135-141.
- doi: 10.5388/aon.2019.19.3.135
PURPOSE: This study aimed to identify the effects of illness perception and health beliefs on the quality of life (QOL) of breast cancer patients. METHODS: A cross-sectional study was conducted. Data... -
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- Critical effects of long non-coding RNA on fibrosis diseases
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Zhang Y, Luo G, Zhang Y, Zhang M, Zhou J, Gao W, Xuan X, Yang X, Yang D, Tian Z, Ni B, Tang J
- KMID: 2438358
- Exp Mol Med.
- 2018 Jan;50(1):e428.
- doi: 10.1038/emm.2017.223
The expression or dysfunction of long non-coding RNAs (lncRNAs) is closely related to various hereditary diseases, autoimmune diseases, metabolic diseases and tumors. LncRNAs were also recently recognized as functional regulators... -
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- KIF11 Functions as an Oncogene and Is Associated with Poor Outcomes from Breast Cancer
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Zhou J, Chen WR, Yang LC, Wang J, Sun JY, Zhang WW, He ZY, Wu SG
- KMID: 2454312
- Cancer Res Treat.
- 2019 Jul;51(3):1207-1221.
- doi: 10.4143/crt.2018.460
PURPOSE: The study aimed to search and identify genes that were differentially expressed in breast cancer, and their roles in cancer growth and progression. MATERIALS AND METHODS: The Gene Expression Omnibus... -
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- Clinical practice guidelines and real-life practice in hepatocellular carcinoma: A Chinese perspective
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Xie D, Shi J, Zhou J, Fan J, Gao Q
- KMID: 2541400
- Clin Mol Hepatol.
- 2023 Apr;29(2):206-216.
- doi: 10.3350/cmh.2022.0402
Liver cancer is the fourth most prevalent and the second most lethal cancer in China. Hepatitis B virus (HBV) infection represents a major risk factor for hepatocellular carcinoma (HCC). Liver... -
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- Identification of key genes and functional enrichment analysis of liver fibrosis in nonalcoholic fatty liver disease through weighted gene co-expression network analysis
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Hu Y, Zhou J
- KMID: 2550886
- Genomics Inform.
- 2023 Dec;21(4):e45.
- doi: 10.5808/gi.23051
Nonalcoholic fatty liver disease (NAFLD) is a common type of chronic liver disease, with severity levels ranging from nonalcoholic fatty liver to nonalcoholic steatohepatitis (NASH). The extent of liver fibrosis... -
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- Clinical Biomarkers of Neurodegeneration in REM Sleep Behavior Disorder
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Zhou J, Zhang J, Lam SP, Tang X, Wing YK
- KMID: 2223615
- J Sleep Med.
- 2015 Dec;12(2):27-33.
- doi: 10.13078/jsm.15006
Rapid eye movement sleep behavior disorder (RBD) is currently considered as a prodromal stage of alphasynucleinopathies neurodegeneration. The update data suggested that over 80% patients with idiopathic RBD eventually developed... -
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- The Hepatotoxicity and Testicular Toxicity Induced by Arecoline in Mice and Protective Effects of Vitamins C and E
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Zhou J, Sun Q, Yang Z, Zhang J
- KMID: 2285503
- Korean J Physiol Pharmacol.
- 2014 Apr;18(2):143-148.
- doi: 10.4196/kjpp.2014.18.2.143
Arecoline is a major alkaloid of areca nuts which are widely chewed by southeast Asian and it manifests various toxic effects in different organs of human and animals. In this... -
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- Sleep deprivation disrupts the lacrimal system and induces dry eye disease
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Li S, Ning K, Zhou J, Guo Y, Zhang H, Zhu Y, Zhang L, Jia C, Chen Y, Sol Reinach P, Liu Z, Li W
- KMID: 2440046
- Exp Mol Med.
- 2018 Mar;50(3):e451.
- doi: 10.1038/emm.2017.285
Sleep deficiency is a common public health problem associated with many diseases, such as obesity and cardiovascular disease. In this study, we established a sleep deprivation (SD) mouse model using... -
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