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Regulation of Energy and Glucose Homeostasis by the Nucleus of the Solitary Tract and the Area Postrema

Bruce K, Garrido AN, Zhang SY, Lam TK

The central nervous system regulates feeding, weight and glucose homeostasis in rodents and humans, but the site-specific mechanisms remain unclear. The dorsal vagal complex in the brainstem that contains the...
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Risk Factors for Anxiety in Major Depressive Disorder Patients

Xin LM, Chen L, Ji ZP, Zhang SY, Wang J, Liu YH, Chen DF, Yang FD, Wang G, Fang YR, Lu Z, Yang HC, Hu J, Chen ZY, Huang Y, Sun J, Wang XP, Li HC, Zhang JB, Si TM

OBJECTIVE: To analyze the sociodemographic and clinical factors related to anxiety in patients with major depressive disorder (MDD). METHODS: This study involved a secondary analysis of data obtained from the Diagnostic...
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Relationship of Polymorphisms in the Oxidative Stress Related Genes - Paraoxonase and p22phox - to Variant Angina and Coronary Artery Stenosis in Korean

Cho YS, Choi JH, Zhang SY, Lee JH, Hwang KK, Kim HS, Oh BH, Lee MM, Park YB, Choi YS

BACKGROUND AND OBJECTIVES: Oxidative stress plays an important role in the pathogenesis of coronary atherosclerosis and spasm. We investigated whether the polymorphisms in two oxidative stress-related genes, paraoxonase and p22phox,...
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Prevalence and Risk Factors of Cerebral Small Vessel Disease in a Chinese Population-Based Sample

Han F, Zhai FF, Wang Q, Zhou LX, Ni J, Yao M, Li ML, Zhang SY, Cui LY, Jin ZY, Zhu YC

BACKGROUND AND PURPOSE: Epidemiological data of cerebral small vessel disease (CSVD) in the general population of China are lacking. We report on the prevalence of lacunes, white matter hyperintensity (WMH),...
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Six Months Follow Up Results of "Granulocytes-Colony Stimulating Factor" Based Stem Cell Therapy in Patients with Myocardial Infarction: MAGIC Cell Randomized Controlled Trial

Kang HJ, Kim HS, Na SH, Zhang SY, Kang WJ, Youn TJ, Koo BK, Kim YJ, Lee DS, Sohn DW, Han KS, Oh BH, Park YB

BACKGROUND AND OBJECTIVES: Granulocytes-colony stimulating factor (G-CSF) has a stem cell mobilizing capacity and favorable effects on ventricular remodeling following a myocardial infarction. G-CSF based stem cell therapy has shown...
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NF-kappa B decoy potentiates the effects of radiation on vascular smooth muscle cells by enhancing apoptosis

Zhang SY, Park KW, Oh S, Cho HJ, Cho HJ, Park JS, Cho YS, Koo BK, Chae IH, Choi DJ, Kim HS, Lee MM

  • KMID: 1033097
  • Exp Mol Med.
  • 2005 Feb;37(1):18-26.
NF-kappa B promotes cell survival against external stress such as radiation. We examined whether NF-kappa B decoy transfection enhances the antiproliferative effects of radiation on vascular smooth muscle cells (VSMCs)...
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Role of 5-HT2A Receptor Gene T102C Polymorphism in Coronary Artery Disease and Serum Lipid Level

Choi JH, Zhang SY, Cho YS, Whang KK, Lee JH, Oh S, Chae IH, Zo JH, Kim HS, Oh BH, Lee MM, Choi YS, Park YB

BACKGROUND AND OBJECTIVES: The 5-HT2A receptor is one of the main mediators of a serotonin-evoked coronary artery contraction. This is because vasoconstriction is selectively blocked by the 5-HT2 receptor antagonist,...
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