- Human Umbilical Cord Mesenchymal Stem Cells Improve the Necrosis and Osteocyte Apoptosis in Glucocorticoid-Induced Osteonecrosis of the Femoral Head Model through Reducing the Macrophage Polarization
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Tian G, Liu C, Gong Q, Yu Z, Wang H, Zhang D, Cong H
- KMID: 2529834
- Int J Stem Cells.
- 2022 May;15(2):195-202.
- doi: 10.15283/ijsc21120
Background and Objectives: Apoptosis is an outstanding determinant of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been demonstrated to be associated... -
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- Addendum to: Effects of Exercise and a High-Fat, High-Sucrose Restriction Diet on Metabolic Indicators, Nr4a3, and Mitochondria-Associated Protein Expression in the Gastrocnemius Muscles of Mice with Diet-Induced Obesity (J Obes Metab Syndr 2021;30:44-54)
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Lee JH, Zhang D, Kwak SE, Shin HE, Song W
- KMID: 2527743
- J Obes Metab Syndr.
- 2022 Mar;31(1):94-95.
- doi: 10.7570/jomes22018
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- Transcriptome and proteome analysis of pregnancy and postpartum anoestrus ovaries in yak
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Chen Z, Wang J, Ma J, Li S, Huo S, Yang Y, Zhaxi Y, Zhao Y, Zhang D
- KMID: 2525550
- J Vet Sci.
- 2022 Jan;23(1):e3.
- doi: 10.4142/jvs.21195
Background: Domestic yaks are the most important livestock species on the Qinghai-Tibetan Plateau. Adult female yaks normally breed in the warm season (July to September) and enter anestrous in the... -
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- Circ_0001686 Promotes Prostate Cancer Progression by Up-Regulating SMAD3/TGFBR2 via miR-411-5p
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Pan J, Liu Z, Yang Z, Liang E, Fang C, Zhang D, Zhou X, Niu Y, Xin Z, Chen Y, Cai Q
- KMID: 2523644
- World J Mens Health.
- 2022 Jan;40(1):149-161.
- doi: 10.5534/wjmh.200204
Purpose: As the mechanism of interaction between circular RNAs (circRNAs) and microRNAs (miRNAs) in regulating the development of prostate cancer (PCa) is not clear, this study focuses on investigating these... -
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- Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome
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Liu G, Li S, Chen N, Zhao Z, Guo M, Liu H, Feng J, Zhang D, Yao Z, Hu B
- KMID: 2517537
- J Neurogastroenterol Motil.
- 2021 Jul;27(3):426-435.
- doi: 10.5056/jnm20134
Background/Aims Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disease characterized by recurrent abdominal pain and bowel dysfunction. However, the majority of previous neuroimaging studies focus on brain structure and... -
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- Effects of Exercise and a High-Fat, High-Sucrose Restriction Diet on Metabolic Indicators, Nr4a3, and Mitochondria-Associated Protein Expression in the Gastrocnemius Muscles of Mice with Diet-Induced Obesity
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Lee JH, Zhang D, Kwak SE, Shin HE, Song W
- KMID: 2514140
- J Obes Metab Syndr.
- 2021 Mar;30(1):44-54.
- doi: 10.7570/jomes20043
Background: Exercise and high fat, high sucrose restriction diets are well known treatments for obesity. The aim of this study was to measure the effects of those lifestyle interventions on... -
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- Reference Intervals for Thyroid-Associated Hormones and the Prevalence of Thyroid Diseases in the Chinese Population
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Zou Y, Wang D, Cheng X, Ma C, Lin S, Hu Y, Yu S, Xia L, Li H, Yin Y, Liu H, Zhang D, Zhang K, Lian X, Xu T, Qiu L
- KMID: 2512736
- Ann Lab Med.
- 2021 Jan;41(1):77-85.
- doi: 10.3343/alm.2021.41.1.77
Background: Thyroid diseases are highly prevalent worldwide, but their diagnosis remains a challenge. We established reference intervals (RIs) for thyroid-associated hormones and evaluated the prevalence of thyroid diseases in China. Methods:... -
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- Induced Intermediate Mesoderm Combined with Decellularized Kidney Scaffolds for Functional Engineering Kidney
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Zhang J, Li K, Kong F, Sun C, Zhang D, Yu X, Wang X, Li X, Liu T, Shao G, Guan Y, Zhao S
- KMID: 2464070
- Tissue Eng Regen Med.
- 2019 Oct;16(5):501-512.
- doi: 10.1007/s13770-019-00197-9
BACKGROUND: Chronic kidney disease is a severe threat to human health with no ideal treatment strategy. Mature mammalian kidneys have a fixed number of nephrons, and regeneration is difficult once... -
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- Exercise, the Gut Microbiome, and Frailty
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Shin HE, Kwak SE, Lee JH, Zhang D, Bae JH, Song W
- KMID: 2464499
- Ann Geriatr Med Res.
- 2019 Sep;23(3):105-114.
- doi: 10.4235/agmr.19.0014
The gut microbiome is deeply associated with both skeletal muscle and brain function. In particular, gut microbiome dysbiosis may accelerate age-related diseases by affecting these systems. Although there is increasing... -
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- Effect of a Single Bout of Exercise on Autophagy Regulation in Skeletal Muscle of High-Fat High-Sucrose Diet-Fed Mice
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Zhang D, Lee JH, Kwak SE, Shin HE, Zhang Y, Moon HY, Shin DM, Seong JK, Tang L, Song W
- KMID: 2459812
- J Obes Metab Syndr.
- 2019 Sep;28(3):175-185.
- doi: 10.7570/jomes.2019.28.3.175
BACKGROUND: Autophagy maintains metabolic homeostasis of muscles, and its impairment may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long-term high-fat diet. This study aimed to explore the... -
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- miR-195/miR-497 Regulate CD274 Expression of Immune Regulatory Ligands in Triple-Negative Breast Cancer
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Yang L, Cai Y, Zhang D, Sun J, Xu C, Zhao W, Jiang W, Pan C
- KMID: 2429815
- J Breast Cancer.
- 2018 Dec;21(4):371-381.
- doi: 10.4048/jbc.2018.21.e60
PURPOSE: Immune suppression is common in patients with advanced breast cancer but the mechanisms underlying this phenomenon have not been sufficiently studied. In this study, we aimed to identify B7... -
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- Effects of Single Vitamin D₃ Injection (200,000 Units) on Serum Fibroblast Growth Factor 23 and Sclerostin Levels in Subjects with Vitamin D Deficiency
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Zhang D, Seo DH, Choi HS, Park HS, Chung YS, Lim SK
- KMID: 2406189
- Endocrinol Metab.
- 2017 Dec;32(4):451-459.
- doi: 10.3803/EnM.2017.32.4.451
BACKGROUND: Vitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-derived hormone that regulates phosphate and 1,25-dihydroxyvitamin D... -
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- Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model
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Zhang YD, Zhu ZS, Zhang D, Zhang Z, Ma B, Zhao SC, Xue F
- KMID: 2402949
- Exp Mol Med.
- 2017 Dec;49(12):e412.
- doi: 10.1038/emm.2017.220
This study aimed to investigate the effect of Patched-1 (PTC1) and PTC2 silencing in a rat model, on Hedgehog (Hh) pathway-mediated recovery from spinal cord injury (SCI). An analytical emphasis... -
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- Evaluation of expression of the Wnt signaling components in canine mammary tumors via RT² Profiler PCR Array and immunochemistry assays
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Yu F, Rasotto R, Zhang H, Pei S, Zhou B, Yang X, Jin Y, Zhang D, Lin D
- KMID: 2412454
- J Vet Sci.
- 2017 Sep;18(3):359-367.
- doi: 10.4142/jvs.2017.18.3.359
The Wnt signaling pathway and its key component β-catenin have critical roles in the development of diseases such as tumors in mammals. However, little has been reported about involvement of... -
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- Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model
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Park BM, Kim EJ, Nam HJ, Zhang D, Bae CH, Kang M, Kim H, Lee W, Bogen B, Lim SK
- KMID: 2419106
- Yonsei Med J.
- 2017 May;58(3):505-513.
- doi: 10.3349/ymj.2017.58.3.505
PURPOSE: Dickkopf 1 (DKK1) has been extensively investigated in mouse models of multiple myeloma, which results in osteolytic bone lesions. Elevated DKK1 levels in bone marrow plasma and serum inhibit... -
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- Risk Factors for the Rupture of Bifurcation Intracranial Aneurysms Using CT Angiography
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Wang GX, Zhang D, Wang ZP, Yang LQ, Zhang L, Wen L
- KMID: 2374163
- Yonsei Med J.
- 2016 Sep;57(5):1178-1184.
- doi: 10.3349/ymj.2016.57.5.1178
PURPOSE: To investigate the clinical and morphological characteristics in relation to risk of bifurcation intracranial aneurysm rupture. MATERIALS AND METHODS: Data from 202 consecutive patients with 219 bifurcation aneurysms (129 ruptured... -
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- The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study
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Huang J, Zhang D, Xie F, Lin D
- KMID: 2164533
- J Vet Sci.
- 2015 Jun;16(2):225-231.
- doi: 10.4142/jvs.2015.16.2.225
Increasing evidence suggests that cancer stem cells (CSCs) are responsible for tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor... -
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- Weight Gain in Pregnancy, Maternal Age and Gestational Age in Relation to Fetal Macrosomia
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Li Y, Liu QF, Zhang D, Shen Y, Ye K, Lai HL, Wang HQ, Hu CL, Zhao QH, Li L
- KMID: 2279356
- Clin Nutr Res.
- 2015 Apr;4(2):104-109.
- doi: 10.7762/cnr.2015.4.2.104
To investigate the possible risk factors related to macrosomia. Pregnant women and their newborns (n = 1041) were recruited from a cohort study in Maternal and Child Care Center of... -
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- Selective Estrogen Receptor Modulation by Larrea nitida on MCF-7 Cell Proliferation and Immature Rat Uterus
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Ahn HN, Jeong SY, Bae GU, Chang M, Zhang D, Liu X, Pei Y, Chin YW, Lee J, Oh SR, Song YS
- KMID: 2170630
- Biomol Ther.
- 2014 Jul;22(4):347-354.
Larrea nitida is a plant that belongs to the Zygophyllaceae family and is widely used in South America to treat inflammatory diseases, tumors and menstrual pain. However, its pharmacological activity... -
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- Detection of Acute Toxoplasmosis in Pigs Using Loop-Mediated Isothermal Amplification and Quantitative PCR
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Wang Y, Wang G, Zhang D, Yin H, Wang M
- KMID: 1792151
- Korean J Parasitol.
- 2013 Oct;51(5):573-577.
A loop-mediated isothermal amplification (LAMP) assay allows rapid diagnosis of Toxoplasma gondii infection. In the present study, the LAMP assay was evaluated using blood from both naturally and experimentally infected... -
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