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Anti-Tumor Effect of AG60 against Ehrlich Tumor

Lee KY, Yoo BI, Yoon JS, Chung YS, Han YB

  • KMID: 2095361
  • J Korean Surg Soc.
  • 1998 Jun;54(6):765-771.
BACKGROUND: AG60 is a complex of acriflavine and guanosine. Our previous study revealed that AG60 had not only in vitro antitumor activities in several human cancer cell lines, but also...
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Inhibition of Angiogenesis by the First Type I Repeat Peptides of Thrombospondin-1

Yoo BI, Jeong GB

Angiogenesis is the fundamental biological phenomenon in the development of vertebrates and various pathophysiological process such as cancer, inflammation and wound healing. Thrombospondin-1 is a well-known anti-angiogenic molecule which is...
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A Trend Analysis of the Prevalence, Awareness, Treatment, and Control of Hypertension by Age Group

Moon JY, Park KJ, Hwangbo Y, Lee MR, Yoo BI, Won JH, Park YH

  • KMID: 1711356
  • J Prev Med Public Health.
  • 2013 Nov;46(6):353-359.
OBJECTIVES: We examined the trends in prevalence, awareness, treatment, and control of hypertension in Korea as a basis for improving hypertension control programs. METHODS: 12 598 participants of the Korean National...
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Effect of Antioxidant Vitamin Supplementation on Hyperbaric Oxygen Injury in Rats

Jung CK, Yoo BI, Lee KY, Kang CS

  • KMID: 2298436
  • Korean J Aerosp Environ Med.
  • 2004 Dec;14(4):135-141.
BACKGROUND: Antioxidants vitamin C and vitamin E may protect against the toxic effect of oxygen free radicals that are preferentially produced after exposures to hyperbaric oxygen (HBO). This study investigated...
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Anti-tumor Effect of the Complex of Acriflavine and Guanosine (AG60)

Hong EK, Kim HM, Lee KY, Chung YS, Yoo BI, Kim SG, Ahn ET, Han YB

  • KMID: 1531906
  • J Korean Cancer Assoc.
  • 1997 Feb;29(1):29-37.
PURPOSE: The anti-tumor effect of the complex of acriflavine and guanosine (AG60) was investigated. MATERIALS AND METHODS: In vitro cytotoxicity of AG60 was measured using SRB assay, and in vivo...
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Construction and Validation of Brain MRI Templates from a Korean Normal Elderly Population

Lee H, Yoo BI, Han JW, Lee JJ, Oh SY, Lee EY, Kim JH, Kim KW

OBJECTIVE: This study aimed to construct a Korean normal elderly brain template (KNE96) using Korean elderly individuals for use in brain MRI studies and to validate it. METHODS: We used high-resolution...
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Fluorescent Study on the Tissue-Distribution of Acriflavine-Guanosine Compound (AG60)

Ko JS, Yim SJ, Ahn ET, Kim JG, Kim SG, Lee KY, Kang JK, Hong EK, Chung YS, Yoo BI, Han YB

  • KMID: 2224599
  • Korean J Anat.
  • 1999 Feb;32(1):105-116.
The study was carried out to evaluate the tissue-distribution of acriflavine or AG60 (acriflavine-guanosine compound, 1 : 1), the newly developed anticancer remedy. Successful access or distribution of a drug...
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Autoradiographic Study on the Effect of AG60 to the DNA Synthesis of Gastric Epithelium of Mouse Inoculated with Ehrlich Carcinoma

Park KH, Ahn ET, Ko JS, Ha SS, Chung YS, Hong EK, Yoo BI, Kim SG, Lee KY, Kang JK, Han YB

  • KMID: 2224598
  • Korean J Anat.
  • 1999 Feb;32(1):95-104.
To study the tumor-suppression effect of a newly developed anti-tumor agent AG60 [acriflavine (1) : guanosine (1) composition, Taerim Pharm. Co., Seoul, Korea], each Ehrlich carcinoma (10(7) cells)-inoculated mouse received...
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Anticancer Effect of AG60 (Acriflavine-Guanosine Compound) on the Ehrlich Cancer Cells Light Microscopic, Autoradiographic and Electron Microscopic Study

Ahn ET, Ko JS, Kim HJ, Kim SG, Lee KY, Kang JK, Yoo BI, Chung YS, Hong EK, Han YB

  • KMID: 2224573
  • Korean J Anat.
  • 1999 Apr;32(2):117-134.
To evaluate the effect and working mechanism of a newly developed anti-cancer drug, AG60 (acriflavine-guanosine compound, Taerim Pharm. Co. Seoul, Korea), histotologic, autoradiographic and electron microscopic studies were carried out....
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