- Islet Transplantation and Regeneration for Treatment of Diabetes
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Yamada Y
- KMID: 1726146
- Yonsei Med J.
- 2004 Jun;45(Suppl):S53-S55.
- doi: 10.3349/ymj.2004.45.Suppl.53
Islet transplantation has the potential to restore normoglycemia and prevent the development of diabetic complications such as retinopathy, nephropathy and neuropathy, and could therefore ve a valuable treatment for diabetic... -
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- Gene and Cell Replacement via Neural Stem Cells
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Kim HT, Kim IS, Lim SE, Lee IS, Park KI
- KMID: 1726143
- Yonsei Med J.
- 2004 Jun;45(Suppl):S32-S40.
- doi: 10.3349/ymj.2004.45.Suppl.32
Neural stem cells (NSCs) are operationally defined by their ability to self-renew, to differentiate into cells of all glial and neuronal lineages throughout the neuraxis, and to populate developing or... -
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- Gene Therapy and Cell Transplantation for Alzheimer's Disease and Spinal Cord Injury
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Blesch A, Tuszynski
- KMID: 1726142
- Yonsei Med J.
- 2004 Jun;45(Suppl):S28-S31.
- doi: 10.3349/ymj.2004.45.Suppl.28
The targeted delivery of genes and the transplantation of suitable cell types into the adult nervous system have received considerable interest over the last years. The development of improved vector... -
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- Government Regulations on Cellular Therapy and Proposed Approach Related with These Products by KFDA
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Yoo MY
- KMID: 1726137
- Yonsei Med J.
- 2004 Jun;45(Suppl):S5-S6.
- doi: 10.3349/ymj.2004.45.Suppl.5
Advances in biomedical technology has enabled the research and use of novel therapies in cellular transplantation. A number of trials using chondrocyte and autologous skin products are underway and will... -
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- Strategies to Improve Dendritic Cell-based Immunotherapy against Cancer
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Song SY, Kim HS
- KMID: 1726145
- Yonsei Med J.
- 2004 Jun;45(Suppl):S48-S52.
- doi: 10.3349/ymj.2004.45.Suppl.48
Dendritic cells (DCs) play a pivotal role in T cell-mediated immunity and have been shown to induce strong antitumor immune responses in vitro and in vivo. Various approaches utilizing different... -
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- Clinical Results of Transplantation of Tissue-Engineered Cartilage and Future Direction of Cartilage Repair: Novel Approach with Minimally Invasive Procedure
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Ochi M
- KMID: 1726155
- Yonsei Med J.
- 2004 Jun;45(Suppl):S74A6-S74A6.
- doi: 10.3349/ymj.2004.45.Suppl.74A6
Articular cartilage has very limited potential to spontaneously heal, because it lacks vessels and is isolated from systemic regulation. No treatment has repaired the defects with long-lasting hyaline cartilage. Recently,... -
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- Adoptive Immunotherapy for Cytomegalovirus (CMV) Disease in Immunocompromised Patients
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Lim JB, Kwon OH, Kim HS, Kim HO, Choi JR, Provenzano M, Stroncek D
- KMID: 1726140
- Yonsei Med J.
- 2004 Jun;45(Suppl):S18-S22.
- doi: 10.3349/ymj.2004.45.Suppl.18
Cytomegalovirus (CMV) reactivation in immune compromised patients such as those undergoing hematopoietic progenitor cell transplantation (HPCT) and those with HIV infections can cause severe morbidity and mortality despite treatment with... -
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- Autologous Bone Marrow Cell Transplantation Combined with Off-Pump Coronary Artery Bypass Grafting in Human Ischemic Myocardium
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Yoo KJ, Kim HO, Kwak YL, Kang SM, Jang YS, Lim SH, Ahn JY, Li RK
- KMID: 1726153
- Yonsei Med J.
- 2004 Jun;45(Suppl):S73A4-S73A4.
- doi: 10.3349/ymj.2004.45.Suppl.73A4
Recently, autologous bone marrow cell transplantation (CTx) for angiogenesis and myogenesis in ischemic myocardium has been extensively investigated to improve heart function. This study was designed to evaluate the effects... -
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- Biologic Therapy for Brain Cancers - Based on Cellular and Immunobiology
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Okada H
- KMID: 1726149
- Yonsei Med J.
- 2004 Jun;45(Suppl):S68-S70.
- doi: 10.3349/ymj.2004.45.Suppl.68
The overall goal of our research projects is to develop effective immunotherapeutic regimens, particularly combining vaccine and gene therapy/ cell therapy strategies. For the development of clinically effective immunotherapy for... -
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- The Fetal Sheep: A Unique Model System for Assessing the Full Differentiative Potential of Human Stem Cells
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Porada GA, Porada C, Zanjani ED
- KMID: 1726138
- Yonsei Med J.
- 2004 Jun;45(Suppl):S7-S14.
- doi: 10.3349/ymj.2004.45.Suppl.7
The naturally occurring stem cell migratory patterns, the availability of expanding homing and engraftment sites, and the presence of tissue/organ-specific signals in the developing mammalian fetus provide the ideal setting... -
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- Efficient Induction of Dopaminergic Neurons from Embryonic Stem Cells for Application to Parkinson's Disease
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Kim DW
- KMID: 1726141
- Yonsei Med J.
- 2004 Jun;45(Suppl):S23-S27.
- doi: 10.3349/ymj.2004.45.Suppl.23
For cell replacement therapy of neurodegenerative diseases such as Parkinson's disease (PD), methods for efficiently generating midbrain dopaminergic (DA) neurons from embryonic stem (ES) cells have been investigated. Two aspects... -
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- Clinical Application of Marrow Mesenchymal Stem Cells for Hard Tissue Repair
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Ohgushi H, Kitamura S, Kotobuki N, Hirose M, Machida H, Muraki K, Takakura Y
- KMID: 1726148
- Yonsei Med J.
- 2004 Jun;45(Suppl):S61-S67.
- doi: 10.3349/ymj.2004.45.Suppl.61
Human marrow mesenchymal stem cells were cultured in a medium containing glycerophosphate, ascorbic acid, and dexamethasone (Dex) on alumina ceramic discs and on tissue culture polystyrene (TCPS) dishes. Cell proliferation... -
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- Cell Processing: Current Status and Future Directions
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Stroncek D, Read EJ
- KMID: 1726136
- Yonsei Med J.
- 2004 Jun;45(Suppl):S1-S4.
- doi: 10.3349/ymj.2004.45.Suppl.1
Specialized clinical cell processing began in the Department of Transfusion Medicine at the National Institutes of Health in 1984. The number and complexity of procedures performed increased quickly and in... -
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- Expansion and Differentiation of Dendritic Cells in Clinical Scale from Human Cord CD34+ Progenitor Cells
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Kim HO
- KMID: 1726150
- Yonsei Med J.
- 2004 Jun;45(Suppl):S71A1-A71A1.
- doi: 10.3349/ymj.2004.45.Suppl.71A1
Dendritic cells are the most potent antigen presenting cells and appear to be the only cell type capable of limiting a primary T-cell dependent immune response. Recently, progress in the... -
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- Caged Pancreatic Islet for IDDM
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Bae YH
- KMID: 1726147
- Yonsei Med J.
- 2004 Jun;45(Suppl):S56-S60.
- doi: 10.3349/ymj.2004.45.Suppl.56
The goals of this research are to improve the functionality (insulin secretion rate and pattern) and to expand the life-span of immunoprotected pancreatic islets. The low functionality (less than 15%... -
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- Cell Transplantation to Improve Heart Function: Cell or Matrix
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Li RK
- KMID: 1726152
- Yonsei Med J.
- 2004 Jun;45(Suppl):S72A3-S73A3.
- doi: 10.3349/ymj.2004.45.Suppl.72A3
Current attempts to regenerate the damaged myocardium after myocardial infarction have primarily focused on therapies directed at increasing regional perfusion and reducing cell loss. Accumulating evidence suggests that implantation of... -
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- Chondrogenic Differentiation of Mesenchymal Stem Cells and Its Clinical Applications
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Lee JW, Kim YH, Kim SH, Han SH, Hahn SB
- KMID: 1726144
- Yonsei Med J.
- 2004 Jun;45(Suppl):S41-S47.
- doi: 10.3349/ymj.2004.45.Suppl.41
Tissue engineering has the potential to provide cartilaginous constructs capable of restoring the normal function of native articular cartilage following joint injury or degradation. One approach to functional tissue engineering... -
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- Mechanism of Immune Response During Immunotherapy
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Panelli MC, Nagorsen D, Wang E, Monsurro V, Jin P, Katia Z, Smith K, Ngalame Y, Marincola
- KMID: 1726139
- Yonsei Med J.
- 2004 Jun;45(Suppl):S15-S17.
- doi: 10.3349/ymj.2004.45.Suppl.15
Tumor immunology embraces an extensive array of biological phenomena that include interactions between neoplastic cells and the innate and adaptive immune response. Among immune cells, T cells have taken the... -
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- Mid-term Clinical Results of Tissue-Engineered Vascular Autografts Seeded with Autologous Bone Marrow Cells
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Shin'oka T
- KMID: 1726154
- Yonsei Med J.
- 2004 Jun;45(Suppl):S73A5-S74A5.
- doi: 10.3349/ymj.2004.45.Suppl.73A5
OBJECTIVE: Prosthetic and bioprosthetic materials currently in use lack growth potential and therefore must be repeatedly replaced in pediatric patients as they develop. Tissue engineering (TE) is a new... -
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- Role of Exocrine Pancreatic Progenitor Cells in Pancreatic Carcinogenesis
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Song SY
- KMID: 1726156
- Yonsei Med J.
- 2004 Jun;45(Suppl):S74A7-S75A7.
- doi: 10.3349/ymj.2004.45.Suppl.74A7
Elucidating the mechanisms that regulates proliferation and differentiation in the pancreas and understanding the mechanisms leading to neoplastic transformation are essential steps for the development of novel diagnostic and therapeutic... -
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