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Necrotizing Soft-Tissue Infections: A Retrospective Review of Predictive Factors for Limb Loss

Park HG, Yang JH, Park BH, Yi HS

Background: Emergent diagnosis and treatment are important for the survival of patients with necrotizing soft-tissue infections (NSTIs). Death is the most catastrophic outcome, but limb loss is also one of...
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Impact of COVID-19-Related Stress and Depression in Public Sector Workers

Park J, Cho Hm, Ko Ms, Chi Sh, Han C, Yi Hs, Lee MS

Objectives:The coronavirus disease 2019 (COVID-19) outbreak is a global medical crisis imposing particular burden on public sector employees. The aim of this study was to investigate the psychiatric distress among...
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Impact of the Coronavirus Disease Pandemic on Mental Health among Local Residents in Korea: a Cross Sectional Study

Ko M, Cho Hm, Park J, Chi S, Han C, Yi Hs, Lee MS

Background: This study aimed to evaluate traumatic stress and mental health problems associated with the prolonged coronavirus disease pandemic and to determine the differences across different age groups. Methods: A total...
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A Rare Case of Calcinosis Cutis: Easily Mistaken as a Foreign Body

Kim HI, Kim HS, Yi HS, Kim HY, Kim YS

Calcinosis cutis is a very rare disease characterized by insoluble calcium salt deposits in the skin. There are five types of calcinosis, dystrophic type being the most common among them....
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Reconstruction of a small defect of the lower vermilion adjacent to white roll using a modified O-Z flap

Kim HI, Kim HS, Park JH, Yi HS, Kim YS, Kim HY

Reconstruction of lip defects is important because the lips play an important role in maintaining aesthetic facial balance, facial expressions, and speech. There are various methods of lip reconstruction such...
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Expression of LONP1 Is High in Visceral Adipose Tissue in Obesity, and Is Associated with Glucose and Lipid Metabolism

Lee JH, Jung SB, Lee SE, Kim JE, Kim JT, Kang YE, Kang SG, Yi HS, Ko YB, Lee KH, Ku BJ, Shong M, Kim HJ

Background: The nature and role of the mitochondrial stress response in adipose tissue in relation to obesity are not yet known. To determine whether the mitochondrial unfolded protein response (UPRmt)...
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Experimentally induced fat embolism syndrome: shift from obstruction to toxic effects

Kim HI, In SK, Yi HS, Kim HY, Kim YS

Background Two hypothetical mechanisms have been proposed for fat embolism syndrome: mechanical obstruction and biochemical reactions. However, it has not been proven whether these mechanisms are correlated. This study aimed...
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Predictive factors of drainage volume and drain duration after the inframammary approach to nipple-areolar-complex sparing mastectomy and implant-based breast reconstruction

Kim YS, Kim HS, Park EJ, Kim HY, Kim HI, Park JH, Jeon CW, Yi HS

Background The placement of a closed suction drain is indispensable for preventing serious infections; however, closed suction drains are inevitably accompanied by increases in local infections, pain, and length of...
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Retrospective review of 108 breast reconstructions using the round block technique after breast-conserving surgery: Indications, complications, and outcomes

In SK, Kim YS, Kim HS, Park JH, Kim HI, Yi HS, Park JC, Jeon CW, Choi JH, Jung SU, Kim HY

Background Several oncoplastic approaches have been implemented in recent years to enhance cosmetic results and to reduce complications. The round block technique is a volume displacement technique for breast reconstruction...
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A Case of Odontogenic Fistula Misdiagnosed as Cutaneous Ulcer on the Alar-Facial Angle

Kim YS, Kim BS, Kim HS, In SK, Yi HS, Kim HI, Park JH, Kim HY

Odontogenic cutaneous fistula of dental origin at the alar-facial groove is rarely reported. As many patients present with only skin lesions without dental problems, it is often confused with a...
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Clinical Implication of World Health Organization Classification in Patients with Follicular Thyroid Carcinoma in South Korea: A Multicenter Cohort Study

Jin M, Kim ES, Kim BH, Kim HK, Yi HS, Jeon MJ, Kim TY, Kang HC, Kim WB, Shong YK, Kim M, Kim WG

Background: The study aimed to compare the prognostic value of the 4th edition of World Health Organization classification (WHO-2017) with the previous WHO classification (WHO-2004) for follicular thyroid carcinoma (FTC). Methods:...
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Oncoplastic breast reduction using the short scar periareolar inferior pedicle reduction technique

Kim YS, Kim BS, Kim HS, In SK, Yi HS, Kim HI, Park JH, Choi JH, Kim HY

After a partial mastectomy, large or ptotic breasts can be reconstructed using breast reduction techniques. Wise-pattern reduction is typically used to remove masses in any quadrant of the breast, but...
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Chronic Ulcer on Flank Region as First Manifestation of Crohn’s Disease

Kim HS, In SK, Kim BS, Park JH, Yi HS, Kim HI, Kim YS, Kim HY

Crohn’s disease is difficult to diagnose owing to its varied symptoms, among which fistulae are a late-stage symptom that appears mainly in the form of a perianal fistula. A patient...
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The Significance of Transcriptomic Signatures in the Multifocal Papillary Thyroid Carcinoma: Two mRNA Expression Patterns with Distinctive Clinical Behavior from The Cancer Genome Atlas (TCGA) Database

Kang YE, Hwang B, Lee JH, Shong M, Yi HS, Koo BS, Lee DJ

Background and Objectives: The association between multifocal papillary thyroid carcinoma (PTC) and tumor aggressiveness remains controversial. The aim of study is to evaluate molecular subtypes of multifocal PTCs using multiplatform...
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Modification of the Tumor-Node-Metastasis Staging System for Differentiated Thyroid Carcinoma by Considering Extra-Thyroidal Extension and Lateral Cervical Lymph Node Metastasis

Kim M, Kim WG, Jeon MJ, Kim HK, Yi HS, Kim ES, Kim BH, Kim WB, Shong YK, Kang HC, Kim TY

BACKGROUND: Concerns have arisen about the classification of extra-thyroidal extension (ETE) and lateral cervical lymph node metastasis (N1b) in the 8th edition of the tumor-node-metastasis staging system (TNM-8). This study...
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Factors affecting mastectomy specimen density in direct-to-implant breast reconstruction

Yi HS, In SK, Kim HS, Park JH, Kim HI, Jeon CW, Kim HY

BACKGROUND: Direct-to-implant breast reconstruction following nipple-sparing mastectomy is becoming increasingly common. The weight of the breast specimen informs implant selection. However, specimens of the same weight may have different volume....
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Treatment of post-traumatic chin deformities using bilateral botulinum toxin injections

Park EJ, In SK, Yi HS, Kim HI, Kim HS, Kim HY

Post-traumatic hematoma formation is a common complication of contusion. If the hematoma is large enough to aspirate or drain, it can be treated quickly and appropriately. However, if the hematoma...
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Malignant Hepatic Solitary Fibrous Tumor

Kim HI, In SK, Yi HS, Lee MJ, Kim HY

Hepatic solitary fibrous tumors (SFTs) are mostly benign and rare because of information regarding the clinical symptoms, treatment, and prognosis of their malignant forms is currently lacking. A literature review...
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Serum R-Spondin 1 Is a New Surrogate Marker for Obesity and Insulin Resistance

Kang YE, Kim JM, Yi HS, Joung KH, Lee JH, Kim HJ, Ku BJ

BACKGROUND: Recent in vivo studies indicated that R-spondin 1 (RSPO1) regulates food intake and increases insulin secretion, but its role in humans remains unknown. This study investigated the association between...
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Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases

Yi HS

The signaling network of the mitochondrial unfolded protein response (UPR(mt)) and mitohormesis is a retrograde signaling pathway through which mitochondria-to-nucleus communication occurs in organisms. Recently, it has been shown that...
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