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Anti-Müllerian Hormone Negatively Regulates Osteoclast Differentiation by Suppressing the Receptor Activator of Nuclear Factor-κB Ligand Pathway

Kim JH, Yang YR, Kwon KS, Kim N

Background: Multiple members of the transforming growth factor-β (TGF-β) superfamily have well-established roles in bone homeostasis. Anti-Müllerian hormone (AMH) is a member of TGF-β superfamily of glycoproteins that is responsible...
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Oxaliplatin-induced Peripheral Neuropathy, Symptoms, Distress and Quality of Life among Korean Patients with Gastrointestinal Cancer

Jung HJ, Ahn SJ, Yang YR, Kim KA, Shin SJ, Jung MK, Chu SH

PURPOSE: This study was conducted to identify the level of oxaliplatin-induced peripheral neuropathy (OIPN), symptoms, distress, and quality of life (QoL) in gastrointestinal (GI) cancer patients and to identify the...
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Patient's Factors at Entering Hospice Affecting Length of Survival in a Hospice Center

Lee GJ, Ahn HS, Go SE, Kim JH, Seo MW, Kang SH, Yang YR, Lee MY, Lee KO, Chun SH, Jin JY

PURPOSE: In order to provide effective hospice care, adequate length of survival (LOS) in hospice is necessary. However the reported average LOS is much shorter. Analysis of LOS in hospice...
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A Case of Descending Thoracic and Abdominal Aortic Aneurysm with Ankylosing Spondylitis

Yang YR, Lee RS, Ban TH, Seo JH, Kim DJ, Jung SM, Park SH

Ankylosing spondylitis (AS) is a systemic inflammatory disorder that affects the axial skeleton. It often involves the extra-articular organs. Cardiovascular involvement is one of the extra-articular manifestations, which is mostly...
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Intussusception Induced by Cecal Metastasis of Primary Small Cell Lung Cancer

Sun DS, Lee H, Lee JS, Yang YR, Kim CH, Shim BY, Kim HK

  • KMID: 2267818
  • Korean J Med.
  • 2013 Aug;85(2):218-222.
Large bowel metastasis from a primary lung cancer is rare and is hard to be asymptomatic. We report a case of intussusception without any symptoms caused by cecal metastasis of...
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A Case of Alternaria Rhinosinusitis in a Patient with Myelodysplastic Syndrome during Neutropenic Period

Heo JY, Yang YR, Kim JW, Choi JK, Park M, Lim YJ, Hong KW, Lee DG, Eom KS, Kim YJ

The genus Alternaria contains several species of melanized hypomycetes that cause opportunistic human infections. The most frequent clinical manifestations of alternariosis are cutaneous and subcutaneous infections, followed by oculomycosis, invasive...
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Phosphatidylinositol phosphates directly bind to neurofilament light chain (NF-L) for the regulation of NF-L self assembly

Kim SK, Kim H, Yang YR, Suh PG, Chang JS

Phosphatidylinositol phosphates (PtdInsPs) are ubiquitous membrane phospholipids that play diverse roles in cell growth and differentiation. To clarify the regulation mechanism acting on neurofilament light chain (NF-L) self assembly, we...
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A double point mutation in PCL-gamma1 (Y509A/F510A) enhances Y783 phosphorylation and inositol phospholipid-hydrolyzing activity upon EGF stimulation

Chung SH, Kim SK, Kim JK, Yang YR, Suh PG, Chang JS

Growth factor stimulation induces Y783 phosphorylation of phosphoinositide-specific PLC-gamma1, and the subsequent activation of this enzyme in a cellular signaling cascade. Previously, we showed that a double point mutation, Y509A/F510A,...
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A Study of Patients with Spasm of the Near Reflex

Yang YR, Koh JW, Choi NY, Park SC

  • KMID: 2337427
  • J Korean Ophthalmol Soc.
  • 2006 Oct;47(10):1630-1637.
PURPOSE: To determine changes in the degree of pseudomyopia and convergence in patients with spasm of the near reflex. METHODS: In 5 patients with spasm of the near reflex, we checked...
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The Effects of Glucose Concentrations on Reactive Oxygen production and Cellular Activity in Retinal Pigment Epithelial Cells

Yang YR, Kim SI, Koh JW

  • KMID: 2208440
  • J Korean Ophthalmol Soc.
  • 2006 Jul;47(7):1126-1131.
PURPOSE: To investigate the effects of glucose concentrations on formation of reactive oxygen products and cellular activity in human retinal pigment epithelial cells. METHODS: Human retinal pigment epithelial cells were cultured...
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The Effects of Glucose Concentrations on Reactive Oxygen products in Human Lens Epithelial Cells

Yang YR, Lee BR, Koh JW

  • KMID: 2337384
  • J Korean Ophthalmol Soc.
  • 2006 May;47(5):828-833.
PURPOSE: To investigate the effects of glucose concentrations on the formation of reactive oxygen products and cellular injury in human lens epithelial (HLE) cells. METHODS: Human lens epithelial (HLE) cells were...
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Minimal Requirement of Limbal Epithelium for Successful Limbal Cell Transplantation in Rabbit Corneas

Yang YR, Choi NY, Kim JH, Kim MS

  • KMID: 2337329
  • J Korean Ophthalmol Soc.
  • 2006 Apr;47(4):613-620.
PURPOSE: To investigate the minimal requirements of the limbal epithelium for successful limbal stem cell transplantation and the healing process. METHODS: Nine rabbits were divided into 4, 6, and 8 clock-hour...
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