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CTNNB1 Mutation in Aldosterone Producing Adenoma

Wang JJ, Peng KY, Wu VC, Tseng FY, Wu KD

Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described...
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Psoas Abscess Caused by Non-Typhoid Salmonella in a Patient with Severe Aplastic Anemia

Kuo CC, Ku SC, Wang JT, Tsai CW, Wu VC, Chou WC

The clinical spectrum of infections caused by non-typhoid Salmonella spp. includes gastroenteritis, enteric fever, bacteremia, and extraintestinal localized complications, especially in immunocompromised hosts. Here we report a patient with severe...
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Primary Aldosteronism and Cerebrovascular Diseases

Chen ZW, Hung CS, Wu VC, Lin YH, the TAIPAI study group

As diagnostic techniques have advanced, primary aldosteronism (PA) has emerged as the most common cause of secondary hypertension. The excess of aldosterone caused by PA resulted in not only cardiovascular...
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Changes in Glucose Metabolism after Adrenalectomy or Treatment with a Mineralocorticoid Receptor Antagonist for Primary Aldosteronism

Lin YF, Peng KY, Chang CH, Hu YH, Wu VC, Chung SD, Taiwan Primary Aldosteronism Investigation (TAIPAI) Study Group

Background: Data on the effects of excess aldosterone on glucose metabolism are inconsistent. This study compared the changes in glucose metabolism in patients with primary aldosteronism (PA) after adrenalectomy or...
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Abrupt Decline in Estimated Glomerular Filtration Rate after Initiating Sodium-Glucose Cotransporter 2 Inhibitors Predicts Clinical Outcomes: A Systematic Review and Meta-Analysis

Chuang MH, Tang YS, Chen JY, Pan HC, Liao HW, Chu WK, Cheng CY, Wu VC, Heung M

Background: The initiation of sodium-glucose cotransporter-2 inhibitors (SGLT2i) typically leads to a reversible initial dip in estimated glomerular filtration rate (eGFR). The implications of this phenomenon on clinical outcomes are...
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