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The Loss of E-cadherin is Associated with the Epigenetic Alteration of CDH1 in Breast Cancer and it is also Associated with an Abnormal beta-catenin Expression in Lobular Carcinoma

Kim G, Kim JY, An HJ, Kang H, Kim TH, Shim JY, Heo JH, Park HL, Choi YK

BACKGROUND: APC and E-cadherin are the key molecules in the Wnt/beta-catenin pathway. We attempted to define the epigenetic alteration of APC and CDH1 (the E-cadherin gene) and the expression of...
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Effects of Wnt-1 on the Growth and Apoptosis of FRTL-5 Cells

Kim JM, Kim TY, Shong YK, Rhee YS, Park EJ, Choi HC, Kim WB

BACKGROUND: Wnt proteins are major signaling molecules involved in embryonic induction, generation of cell polarity and the cell fate decision. A central player in the Wnt signaling pathways is beta-catenin....
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Disturbed Osteoblastic Differentiation of Fibrous Hamartoma Cell from Congenital Pseudarthrosis of the Tibia Associated with Neurofibromatosis Type I

Lee DY, Cho TJ, Lee HR, Lee K, Moon HJ, Park MS, Yoo WJ, Chung CY, Choi IH

BACKGROUND: Fibrous hamartoma is the key pathology of congenital pseudarthrosis of the tibia (CPT), which was shown to have low osteogenicity and high osteoclastogenicity. This study further investigated the mechanism...
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