- Activities of Hepatic Antioxidant Enzymes in Rats during 14 Days of Head-down Suspension as a Model of Simulated Weightlessness
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Bae JH, Park WK, Song DK, Chae EU, Kwak CS, Kim YH, Mun KC
- KMID: 2092978
- Korean J Aerosp Environ Med.
- 1997 Dec;7(4):44-50.
Cells and tissues of human and animal are protected against free radicals by several complex mechanisms including the action of antioxidant enzymes, such as superoxide dismutase (SOD), glutathione peroxidase (GSH-Px)... -
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- Changes of Catecholamine Metabolic Enzymes in Rat Liver during 2 Weeks of Head-down Suspension
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Bae JH, Mun KC
- KMID: 1544401
- Korean J Aerosp Environ Med.
- 1997 Sep;7(3):44-49.
During simulated weightlessness and spaceflight, variations in plasma and urinary catecholamine(GA) levels haute been observed. The alterations of metabolism of CA In liver, the main site of metabolism, ate yet... -
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- Use of Parabolic Flight for the Research of Aerospace Biomedicine
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Kim YH, Lee JH, Ryoo CK, Kim HJ, Kim KS
- KMID: 1967462
- Res Vestib Sci.
- 2015 Jun;14(2):42-45.
- doi: 10.0000/rvs.2015.14.2.42
As it is difficult to perform biological study in the actual space, several researchers have tried to develop methods that could 'mimic' microgravity condition on Earth. During the free fall... -
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- Mechanism of Renal Oxidative Damage following 4-week Head-down Suspension in Rats
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Bae JH, Mun KC, Kwak CS, Song DK, Park WK
- KMID: 2298549
- Korean J Aerosp Environ Med.
- 2000 Jun;10(2):113-119.
The purpose of this study was to observe the variation of malondialdehyde (MDA), an indirect index of oxidative damage, following 4-week of head-down suspension (HDS) at -45degreein rats as a... -
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- Why to Keep Osteocytes Alive and How?
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Bellido T
- KMID: 1468538
- J Korean Endocr Soc.
- 2009 Dec;24(4):223-226.
- doi: 10.3803/jkes.2009.24.4.223
It has been long proposed that the osteocyte network continually compares present mechanical strains to usual levels of strain, and triggers signals to osteoclasts or osteoblasts resulting in bone loss... -
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- Perception during Centrifugation under Microgravity
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Koizuka I, Clement G, Cohen B, Kubo T
- KMID: 2316775
- Res Vestib Sci.
- 2009 Jun;8(1):83-83.
No abstract available. -
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- Expression of Atrial Natriuretic Peptide mRNA during 2 Weeks of Head-down Suspension in Rats
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Bae JH, Hong YS, Song DK, Chae EU, Baek WK, Suh SI, Suh MH, Kim SH, Park WK
- KMID: 2221396
- Korean J Aerosp Environ Med.
- 1997 Mar;7(1):71-80.
The aim of this study was to determine the adaptation of atrial natriuretic peptide(ANP) to simulated weightlessness. The level of immunoreactive plasma ANP level and the expression of right atrial... -
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- Effects of Changes in Mechanical Loading on Endochondral Bone Formation in Hindlimb-suspended Rats
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Park KB, Joo SY, Kong SY, Kang HJ, Park JH, Kim HW
- KMID: 1589165
- Korean J Aerosp Environ Med.
- 2005 Dec;15(3):100-105.
BACKGROUND: To examine the effects of changes in mechanical loading on endochondral bone formation, a simulated rat model of weightlessness was introduced and the changes in the growth plate were... -
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- Altered Cellular Kinetics in the Growth Plate according to Alterations in the Weight Bearing
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Kang HJ, Kong SY, Park KB, Joo SY, Yang IH, Park HW, Kim HW
- KMID: 2199123
- J Korean Orthop Res Soc.
- 2005 Apr;8(1):50-57.
PURPOSE: To examine the effects of change in the weight bearing on the growth plate metabolism, a simulated animal model of weightlessness was introduced and the chondrocytes' cellular kinetics were... -
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- Bone Mineral Density and Osteoporotic Vertebral Fractures in Traditional, Unassisted, Free-Diving Women (Haenyeos)
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Seo JY, Ha KY, Kim YH, Kim SC, Yoon EJ, Park HY
- KMID: 2426666
- J Korean Med Sci.
- 2018 Nov;33(48):e316.
- doi: 10.3346/jkms.2018.33.e316
BACKGROUND: Water pressure and muscle contraction may influence bone mineral density (BMD) in a positive way. However, divers experience weightlessness, which has a negative effect on BMD. The present study... -
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- Introduction to aerospace medicine
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Lim J
- KMID: 2192727
- J Korean Med Assoc.
- 2012 Jul;55(7):649-656.
- doi: 10.5124/jkma.2012.55.7.649
Recent reports show that over 2 billion people are travelling via air every year, and the number of countries involved in space exploration is growing. Aerospace medicine, one of the... -
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- Impaired but reversible vascular reactivity in a rat model of microgravity
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Kim SY, Lim HK, Lee YB, Choi JC, Park JT, Ahn MC, Lee KH
- KMID: 2243002
- Korean J Anesthesiol.
- 2008 Nov;55(5):602-606.
- doi: 10.4097/kjae.2008.55.5.602
BACKGROUND: The hindlimb unweighting (HLU) rat model mimics cardiovascular deconditioning following microgravity or human bed rest, particularly for the development of orthostatic intolerance. We have examined vascular responses to alpha1... -
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- Hypertensive Arterial Change in Hindlimb Unloading Rats
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Hwang SH, Koo JS
- KMID: 1524934
- Korean J Aerosp Environ Med.
- 2007 Dec;17(3):103-107.
BACKGROUND: In a condition of microgravity, arteries of upper body part are exposed to relative hypertensive stress, which is induced by headward fluid shift. We already have reported the increase... -
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- Changes in Hypothalamic Expressions of Natriuretic Peptide mRNA following Head-down Suspension in Rats
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Bae JH, Song DK, Shin DH
- KMID: 2298459
- Korean J Aerosp Environ Med.
- 2003 Mar;13(1):7-12.
BACKGROUND: Head-down suspension (HDS) of rats has been used as a model for simulation of a microgravity environment. C-type natriuretic peptides (CNP) and atrial natriuretic peptide (ANP) are produced in... -
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- Morphological changes in rat testes after Hindlimb Unloading model
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Ahn HC, Kim CH, Im JH, Lee GH, Lee S, Park MJ, Kim C
- KMID: 1511756
- Korean J Aerosp Environ Med.
- 2006 Dec;16(3):49-56.
BACKGROUND: The purpose of this study was to examine histological changes of testes induced by hindlimb unloading & position change of testis in mature adult male rats. METHOD: Eight month old... -
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- Cardiovascular Effects of Hind-limb Unweighing in Mice
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Lee YB, Park JT, Lim HK, Choi JC, Kim SY, Cho JH, Lee KH
- KMID: 2243377
- Korean J Anesthesiol.
- 2007 Aug;53(2):222-228.
- doi: 10.4097/kjae.2007.53.2.222
BACKGROUND: Orthostatic intolerance is a debilitating problem that can occur after prolonged bed-rest, exposure to microgravity, and in the elderly. This study examined the integrated cardiovascular response to baroreceptor activation... -
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- Effects of Long-Term Head-down Suspension on Changes in Body Weight, Daily Water Intake and Hematological Data in Rats
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Bae JH, Song DK, Kim DK
- KMID: 1602570
- Korean J Aerosp Environ Med.
- 2002 Jun;12(2):65-71.
BACKGROUND: This study was aimed to observe the changes in body weight, water intake and hematological data during and after long-term head-down suspension (HDS) in rats. HDS rats induced by... -
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- Changes in Renal Expression of Natriuretic Peptides and Their Receptors mRNA Induced by Head-down Suspension in Rats
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Bae JH, Hwang JS
- KMID: 1517671
- Korean J Aerosp Environ Med.
- 2003 Dec;13(4):184-189.
BACKGROUND: Head-down suspension (HDS) of rats has been used as a model for the simulation of a microgravity environment. Atrial natriuretic peptide (ANP), C-type natriuretic peptides (CNP) and their receptors... -
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- Cardiac expressions of natriuretic peptide mRNA following 4 weeks of head-down suspension in rat
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Hoon BJ, Kyu SD, Kyun PW
- KMID: 2030706
- Korean J Aerosp Environ Med.
- 2000 Dec;10(4):322-328.
BACKGROUND: Head-down suspension (HDS) of rats has evolved as a useful model for the simulation of a microgravity environment. Atrial natriuretic peptides (ANP) and brain natriuretic peptide (BNP) have been... -
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- Effect of Long-Term Antiorthostatic Suspension in a Murine Model of Acute Lung Injury
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Jang TY, Jung AY, Kim YH
- KMID: 2360764
- Clin Exp Otorhinolaryngol.
- 2016 Dec;9(4):332-338.
- doi: 10.21053/ceo.2015.01599
OBJECTIVES: Antiorthostatic suspension (AOS) is ground-based model of simulated microgravity. There is still no study about the effect of long-term microgravity on the clinical course of acute lung injury. We... -
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