- Hepatitis C virus: virology and life cycle
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Kim CW, Chang KM
- KMID: 1493570
- Clin Mol Hepatol.
- 2013 Mar;19(1):17-25.
- doi: 10.3350/cmh.2013.19.1.17
Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV infection can... -
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- Intestinal and Hepatic Niemann-Pick C1-Like 1
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Park SW
- KMID: 2174264
- Diabetes Metab J.
- 2013 Aug;37(4):240-248.
- doi: 10.4093/dmj.2013.37.4.240
Polytopic transmembrane protein, Niemann-Pick C1-Like 1 (NPC1L1) is localized at the apical membrane of enterocytes and the canalicular membrane of hepatocytes. It mediates intestinal cholesterol absorption and prevents extensive loss... -
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- In vivo Study on the Japanese Encephalitis: Viral Localization and Histopathology in the Mouse Brain
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Kim IB, Chae SL, Choi WY, Park C, Joo YR, Cho HW, Park KY
- KMID: 2092812
- Korean J Anat.
- 2003 Oct;36(5):427-433.
Japanese encephalitis is a potentially lethal disease of the central nervous system caused by infection with Japanese encephalitis virus (JEV). JEV is the most common cause of encephalitis over a... -
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- From DCPD to NTCP: The long journey towards identifying a functional hepatitis B virus receptor
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Li J, Tong S
- KMID: 2351018
- Clin Mol Hepatol.
- 2015 Sep;21(3):193-199.
- doi: 10.3350/cmh.2015.21.3.193
Hepatitis B virus (HBV) is the prototype of hepatotropic DNA viruses (hepadnaviruses) infecting a wide range of human and non-human hosts. Previous studies with duck hepatitis B virus (DHBV) identified... -
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- Herpes Virus Entry Mediator Signaling in the Brain Is Imperative in Acute Inflammation-Induced Anorexia and Body Weight Loss
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Kim KK, Jin SH, Lee BJ
- KMID: 1973826
- Endocrinol Metab.
- 2013 Sep;28(3):214-220.
- doi: 10.3803/EnM.2013.28.3.214
BACKGROUND: Reduced appetite and body weight loss are typical symptoms of inflammatory diseases. A number of inflammatory stimuli are responsible for the imbalance in energy homeostasis, leading to metabolic disorders.... -
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- Characterization of Gp41 Polymorphisms in the Fusion Peptide Domain and T-20 (Enfuvirtide) Resistance-Associated Regions in Korean HIV-1 Isolates
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Jang DH, Yoon CH, Choi BS, Chung YS, Kim HY, Chi SG, Kim SS
- KMID: 1734938
- J Korean Med Sci.
- 2014 Mar;29(3):456-459.
- doi: 10.3346/jkms.2014.29.3.456
HIV-1 gp41 is an envelope protein that plays an essential role in virus entry. The mutation of gp41 affects HIV-1 entry and susceptibility to the fusion inhibitor T-20. Therefore, we... -
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- HVEM is a TNF Receptor with Multiple Regulatory Roles in the Mucosal Immune System
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Shui JW, Kronenberg M
- KMID: 2168016
- Immune Netw.
- 2014 Apr;14(2):67-72.
- doi: 10.4110/in.2014.14.2.67
The herpes virus entry mediator (HVEM) is a member of the tumor necrosis factor receptor superfamily (TNFRSF), and therefore it is also known as TNFRSF14 or CD270 (1,2). In recent... -
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- A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice
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Kim DK, Tahara-Hanaoka S, Shinohara , Nakauchi H
- KMID: 1103675
- Exp Mol Med.
- 2007 Feb;39(1):1-7.
CD4 is a cell surface glycoprotein that acts as a co-receptor for the T cell antigen receptor by binding to a non-polymorphic portion of MHC molecules. CD4 also functions as... -
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- New treatments for chronic hepatitis C
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Jang JY, Chung RT
- KMID: 1717320
- Korean J Hepatol.
- 2010 Sep;16(3):263-277.
- doi: 10.3350/kjhep.2010.16.3.263
Treatments for chronic hepatitis C has evolved significantly in the past 15 years. The standard of care (SOC) is peginterferon alfa-2a/-2b with ribavirin for 48 weeks or 24 weeks in... -
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