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The Clinical Efficacy of Pulmonary Hypertension-Specific Agents in Idiopathic Pulmonary Fibrosis: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

Lee J, Song JU

BACKGROUND: Pulmonary hypertension (PH) is common in patients with idiopathic pulmonary fibrosis (IPF) and is associated with poor outcomes. This study was performed to determine the clinical efficacy of PH-specific...
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Pulmonary Hypertension in Newborn Infants with Vein of Galen Malformation

Song WS, Oh MY, Cho JY, Kim CY, Suh DC, Jung E, Kim EA, Kim KS, Lee BS

OBJECTIVE: Vein of Galen malformation (VGM) is a rare cerebrovascular malformation. Children with VGM presenting in newborn period demonstrate various clinical courses from normal development to severe neurologic impairment or...
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Obesity and Erectile Dysfunction: From Bench to Clinical Implication

Moon KH, Park SY, Kim YW

Obesity is a major public health issue worldwide and is frequently associated with erectile dysfunction (ED). Both conditions may share an internal pathologic environment, also known as common soil. Their...
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Reversibility of Pulmonary Hypertension Following Surgical Atrial Septal Defect Closure in Children with Down Syndrome

Lee JS, Cha SG, Kim GB, Lee SY, Song MK, Kwon HW, Bae EJ, Kwak JG, Kim WH, Lee JR

BACKGROUND: Many Down syndrome (DS) patients have an atrial septal defect (ASD) and associated pulmonary hypertension (PH) from early childhood. ASD closure in DS patients with PH is often controversial...
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A Case of Central Serous Chorioretinopathy after Tadalafil Treatment

Yoon YS, Lee S, Woo JM, Min JK

PURPOSE: To describe a patient who presented with central serous chorioretinopathy after 2 months of tadalafil administration without any other underlying disease or medication. CASE SUMMARY: A 49-year-old male patient was...
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Impact of Diltiazem Alone versus Diltiazem with Nitrate on Five-Year Clinical Outcomes in Patients with Significant Coronary Artery Spasm

Park T, Park JY, Rha SW, Seo HS, Choi BG, Choi SY, Byun JK, Park SH, Park EJ, Choi JY, Park SH, Lee JJ, Lee S, Na JO, Choi CU, Lim HE, Kim JW, Kim EJ, Park CG, Oh DJ

PURPOSE: Calcium channel blockers diltiazem and nitrate have been used as selective coronary vasodilators for patients with significant coronary artery spasm (CAS). However, no study has compared the efficacy of...
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Prevalence of Pulmonary Arterial Hypertension in Korean Adult Patients with Systemic Sclerosis: Result of a Pilot Echocardiographic Screening Study

Yoo SJ, Park JH, Park Y, Lee JH, Sun BJ, Kim J, Yoo IS, Shim SC, Kang SW

BACKGROUND: Pulmonary arterial hypertension (PAH) is a major cause of morbidity and mortality among patients with systemic sclerosis (SSc). Early detection and prompt treatment of PAH associated with SSc (SSc-PAH)...
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Survival of the Infants with Bronchopulmonary Dysplasia and Congenital Heart Disease

Jeung MS, Kong YH, Sung SI, Song J

PURPOSE: Pulmonary hypertension is a known risk factor for mortality in preterm infants with bronchopulmonary dysplasia. However, mortality in patients with bronchopulmonary dysplasia and congenital heart disease has been poorly...
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Stepwise Approach Using Combined Management in Patients with Congenital Heart Disease and Borderline Pulmonary Vascular Disease

Lee SY, Kim SJ, Son JS, Kim SH, Lee CH

BACKGROUND AND OBJECTIVES: Despite remarkable advances in pediatric cardiology, pulmonary arterial hypertension associated with congenital heart disease remains a major problem. In the past decade new vasodilators have been introduced...
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Comparison of Prostaglandin E1 and Sildenafil Citrate Administration on Skin Flap Survival in Rats

Choi JA, Lee KC, Kim MS, Kim SK

BACKGROUND: Alprostadil and sildenafil are known vasodilators used independently to improve flap survival in animal models. In this study, we investigate whether these agents act synergistically to decrease flap necrosis...
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Development of Coronary Vasospasm during Adenosine-Stress Myocardial Perfusion CT Imaging

Nam JG, Choi SH, Kang BS, Bang MS, Kwon WJ

Adenosine is a short-acting coronary vasodilator, and it is widely used during pharmacological stress myocardial perfusion imaging. It has a well-established safety profile, and most of its side effects are...
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Current status of penile rehabilitation after radical prostatectomy

Kim JH, Lee SW

Although disease-free survival remains the primary goal of prostate cancer treatment, erectile dysfunction (ED) remains a common complication that affects the quality of life. Even though several preventive and therapeutic...
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Simultaneous Endovascular Treatment of Ruptured Cerebral Aneurysms and Vasospasm

Cho YD, Han MH, Ahn JH, Jung SC, Kim CH, Kang HS, Kim JE, Lim JW

OBJECTIVE: The management of patients with ruptured cerebral aneurysms and severe vasospasm is subject to considerable controversy. We intended to describe herein an endovascular technique for the simultaneous treatment of...
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The Vasodilator Effect of a Cream Containing 10% Menthol and 15% Methyl Salicylate on Random-Pattern Skin Flaps in Rats

Dolen UC, Sungur N, Koca G, Ertunc O, Bagci Bosi AT, Kocer U, Korkmaz M

BACKGROUND: It is still difficult to prevent partial or full-thickness flap necrosis. In this study, the effects of a cream containing menthol and methyl salicylate on the viability of randompattern...
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Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis

Ruaro B, Smith V, Sulli A, Decuman S, Pizzorni C, Cutolo M

Systemic sclerosis is a connective tissue disease characterized by alterations in microvascular structure and function. In these patients, numerous studies have demonstrated a relationship between capillary morphology and peripheral blood...
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A Case of Pulmonary Arterial Hypertension Associated with Congenital Extrahepatic Portocaval Shunt

Yi JE, Jung HO, Youn HJ, Choi JY, Chun HJ, Lee JY

Congenital extrahepatic portocaval shunt (CEPS) is a rare anomaly of the mesenteric vasculature in which the intestinal and splenic venous drainage bypasses the liver and drains directly into the inferior...
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Coronary Spastic Angina and Life Threatening Arrhythmia despite Nitroglycerine Infusion

Shin KH, Cho WH, Lee DH, Lee S, Lim SH

Variant angina pectoris is characterized by chest symptoms at rest and transient ST elevation on the electrocardiography due to coronary artery spasm. Although most patients with coronary spasm respond well...
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Clinical Characteristics and Survival of Korean Idiopathic Pulmonary Arterial Hypertension Patients Based on Vasoreactivity

Ahn JH, Kang BJ, Hong SI, Lee JS, Lee JS, Oh YM, Lee SD

We aimed to identify a vasoreactive subset of patients with idiopathic pulmonary arterial hypertension (IPAH) in Korea and to show their clinical characteristics and prognosis. Data on patients who were...
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Prophylactic Phenylephrine for Iatrogenic Priapism: A Pilot Study With Peyronie's Patients

Jiang P, Christakos A, Fam M, Sadeghi-Nejad H

PURPOSE: Although penile duplex Doppler ultrasonography (PDDU) is a common and integral procedure in a Peyronie's disease workup, the intracavernosal injection of vasoactive agents can carry a serious risk of...
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Rosiglitazone, a Peroxisome Proliferator-Activated Receptor-gamma Agonist, Restores Alveolar and Pulmonary Vascular Development in a Rat Model of Bronchopulmonary Dysplasia

Lee HJ, Lee YJ, Choi CW, Lee JA, Kim EK, Kim HS, Kim BI, Choi JH

PURPOSE: We tested whether rosiglitazone (RGZ), a peroxisome proliferator-activated receptor-gamma agonist, can restore alveolar development and vascular growth in a rat model of bronchopulmonary dysplasia (BPD). MATERIALS AND METHODS: A rat...
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