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The Role of Angiostatin, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9 and 12 in the Angiogenesis of Hepatocellular Carcinoma

Kim S, Park HS, Son HJ, Moon WS

  • KMID: 760532
  • Korean J Hepatol.
  • 2004 Mar;10(1):62-72.
BACKGROUND/AIMS: Tumor angiogenesis, a major requirement for tumor growth and metastasis, is regulated by pro- and anti-angiogenic factors. Hepatocellular carcinoma (HCC) has become a common malignant tumor worldwide. It...
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The Regulators of VEGF Expression in Mouse Ovaries

Shin SY, Lee HJ, Ko DS, Lee HC, Park WI

The objectives of this study were to explore whether ovarian vascular endothelial growth factor (VEGF) expression in mice can be regulated by IL-6 (interleukin-6), angiotensin II, FSH, and hCG; and...
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Engagement of Toll-Like Receptor 3 Induces Vascular Endothelial Growth Factor and Interleukin-8 in Human Rheumatoid Synovial Fibroblasts

Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML, Ju JH, Park KS, Kim HY, Park SH

BACKGROUND/AIMS: Angiogenesis, which is a critical step in the initiation and progression of rheumatoid arthritis (RA), involves pro-angiogenic factors, including interleukin (IL)-8 and vascular endothelial growth factor (VEGF). We investigated...
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An antioxidant modulates expression of receptor activator of NF-kappaB in asthma

Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L, Lee YC

  • KMID: 1094147
  • Exp Mol Med.
  • 2006 Jun;38(3):217-229.
Oxidative stress plays critical roles in airway inflammation that is usually accompanied by increased vascular permeability and plasma exudation. VEGF increases vascular permeability and leads to airway inflammation. In addition,...
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Effect of Helicobacter pylori Eradication According to the IL-8-251 Polymorphism in Koreans

Kang HY, Kim SG, Lee MK, Kim JS, Jung HC, Song IS

Previous studies suggested that polymorphisms of proinflammatory cytokine genes are important host genetic factors in Helicobacter pylori infection. The present study evaluated whether IL-8-251 polymorphism affected H. pylori eradication rate...
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Effects of TNF-alpha on Angiogenesis in CT-26 Mouse Colon Carcinoma Homograft Model

Chun JW, Jung JT, Oh HK, Bae JY, Shin IH, Cho CH

  • KMID: 935194
  • Korean J Gastroenterol.
  • 2005 Dec;46(6):440-446.
BACKGROUND/AIMS: Tumor necrosis factor-alpha (TNF-alpha) exerts its anti-tumor effect through direct cytotoxicity on tumor cells and damage to the tumor vasculature. However, its role in tumor angiogenesis is controversial. We...
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Significance of Microsatellite Instability in Early Gastric Cancer Treated by Endoscopic Submucosal Dissection

Kim KM, Kim YS, Cho JY, Jung IS, Kim WJ, Choi IS, Ryu CB, Kim JO, Lee JS, Jin SY, Shim CS, Kim BS

  • KMID: 1112575
  • Korean J Gastroenterol.
  • 2008 Mar;51(3):167-173.
BACKGROUND/AIMS: Microsatellite instability (MSI) is defined as a change of any length due to either insertion or deletion of repeating units, in a microsatellite within a tumor when compared to...
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