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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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Influenza Vaccine Effectiveness among Elementary School Students in Korea during the 2016-2017 Seasons: a Cross-Sectional Survey

Kim YM, Kang S, Lim JS, Kim DH

BACKGROUND: Annual vaccination is the principal way to reduce the mortality and morbidity associated with influenza. In the 2016–2017 influenza seasons, the influenza epidemic appeared to exhibit a different pattern...
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Cold chain time- and temperature-controlled transport of vaccines: a simulated experimental study

Ng CZ, Lean YL, Yeoh SF, Lean QY, Lee KS, Suleiman A, Liew KB, Kassab YW, Al-Worafi , Ming LC

PURPOSE: The objective of this research was to examine the cold chain temperature maintenance for the supply of vaccines and other biological products by pharmaceutical wholesaler. MATERIALS AND METHODS: In this...
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Verification with the utility of an established rapid assessment of brain safety for newly developed vaccines

Kim GH, Yi SS

In the twenty-first century, high contagious infectious diseases such as SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome), FMD (Foot-and-Mouth Disease) and AI (Avian Influenza) have become very...
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Comparison of Split versus Subunit Seasonal Influenza Vaccine in Korean Children over 3 to under 18 Years of Age

Kang S, Kim DH, Eun BW, Kim NH, Kang EK, Lee BS, Kim YK

PURPOSE: This study was conducted to compare immunogenicities and reactogenicities of the trivalent inactivated subunit influenza vaccine and split influenza vaccine in Korean children and adolescents. METHODS: In total, 202 healthy...
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Introduction of Vaccinomics to Develop Personalized Vaccines in Light of Changes in the Usage of Hantaan Virus Vaccine (Hantavax®) in Korea

Bae JM

The Ministry of Food and Drug Safety of Korea made an official announcement in March 2018 that the total number of inoculations of Hantaan virus vaccine (Hantavax®) would change from...
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Plant factory: new resource for the productivity and diversity of human and veterinary vaccines

Shim BS, Hong KJ, Maharjan P, Choe S

Vaccination is one of the most successful strategies to prevent diseases caused by pathogens. Although various expression systems including Escherichia coli, yeast, insect, and mammalian cells are currently used for...
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Effect of simultaneous administration of foot-and-mouth disease (FMD) and anthrax vaccines on antibody response to FMD in sheep

Çokçalışkan C, Tuncer Göktuna P, Türkoğlu T, Uzunlu E, Gündüzalp C, Uzun EA, Sareyyüpoğlu B, Kürkçü , Gülyaz V

PURPOSE: Foot-and-mouth disease (FMD) and anthrax are important diseases in sheep. Vaccination is a favorable strategy against both infections. Simultaneous administration of vaccines does generally not impede the immune responses...
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Development and implementation of standardized method for detecting immunogenicity of acellular pertussis vaccines in Korea

Park C, Huh DH, Han SB, Choi GS, Kang KR, Kim JA, Kang JH

PURPOSE: There is no standard method for confirming the immunogenicity of acellular pertussis vaccines. We tried to develop a local standard method for evaluating the immunogenicity of the three-component of...
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Vaccines of Our Own

Yoo JH

No abstract available.
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Phase 4, Post-Marketing Safety Surveillance of the MF59-Adjuvanted Influenza Vaccines FLUAD® and VANTAFLU® in South Korean Subjects Aged ≥65 Years

Yoo BW, Kim CO, Izu A, Arora AK, Heijnen E

BACKGROUD: Influenza vaccination is recommended for adults aged ≥65 years as they are at high risk of significant morbidity and mortality. This open-label, multicenter, post-marketing surveillance study assessed the safety...
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Current Approaches in Development of Immunotherapeutic Vaccines for Breast Cancer

Allahverdiyev A, Tari G, Bagirova M, Abamor ES

Cancer is the leading cause of death worldwide. In developed as well as developing countries, breast cancer is the most common cancer found among women. Currently, treatment of breast cancer...
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Validation of a Multiplexed Opsonophagocytic Assay for 11 Additional Pneumococcal Serotypes and Its Application to Functional Antibody Evaluation Induced by Pneumococcal Polysaccharide Vaccine

Cha J, Kim HW, Lee JH, Lee S, Kim KH

BACKGROUND: Various pneumococcal vaccines have been evaluated for immunogenicity by opsonophagocytic assay (OPA). A multiplexed OPA (MOPA) for 13 pneumococcal serotypes was developed by Nahm and Burton, and expanded to...
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Asthma has an adverse effect on the production of antibody to vaccines

Sheen YH

Asthma is considered a chronic inflammatory airway disease. Mounting evidence reports that patients with asthma are at significantly higher risk of developing communicable diseases such as invasive pneumococcal disease, Haemophilus...
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Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards

Choi CW, Moon JH, Kim JO, Yoo SH, Kim HG, Kim JH, Park TJ, Kim SS

OBJECTIVES: Vaccinations against diphtheria and tetanus are essential in providing immunity against these bacterial infections. The potency of diphtheria and tetanus toxoid vaccines can be measured using the in vivo...
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Recent progress in microneme-based vaccines development against Toxoplasma gondii

Foroutan M, Zaki L, Ghaffarifar F

Toxoplasmosis is a cosmopolitan zoonotic disease, which infect several warm-blooded mammals. More than one-third of the human population are seropositive worldwide. Due to the high seroprevalence of Toxoplasma gondii infection...
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The 2nd Meeting of National Control Laboratories for Vaccines and Biologicals in the Western Pacific

Oh H, Shin J, Lee CK, Ochiai M, Nojima K, Lim CK, Raut S, Lisovsky I, Williams S, Yoo KY, Shin DY, Ato M, Ye Q, Han K, Lee C, Lee N, Hong JY, Jung K, Van Hung P, Jeong J

The Second Meeting of the National Control Laboratories for Vaccines and Biologicals in the Western Pacific, was jointly organized by the National Institute of Food and Drug Safety Evaluation of...
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Immunogenicity and Safety of Inactivated Influenza Vaccine in Healthy Korean Children and Adolescent

Ri S, Kim MJ, Kim YK

PURPOSE: This study aimed to evaluate the immunogenicity and safety of a trivalent inactivated influenza vaccine (TIV) among healthy Korean children and adolescents. METHODS: From October to December 2008, 65 healthy...
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Development of New Preventive and Therapeutic Vaccines for Tuberculosis

Kwon BE, Ahn JH, Min S, Kim H, Seo J, Yeo SG, Ko HJ

Tuberculosis (TB) is a contagious disease that has been responsible for the death of one billion people in the last 200 years. Until now, the only vaccine approved for the...
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Safety and Immunogenicity of an Egg-Cultivated Quadrivalent Inactivated Split-virion Influenza Vaccine (GC3110A) in Healthy Korean Children: a Randomized, Double-blinded, Active-controlled Phase III Study

Lee J, Lee KY, Kim JH, Kim CS, Eun BW, Kim HM, Kim DH, Hong YJ, Choi YY, Jo DS, Ma SH, Kang JH

BACKGROUND: The frequency with which the 2 B lineages have been found to cocirculate in a season has been on the rise, which has spurred the need for a quadrivalent...
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