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Recalcitrant Pityriasis Rubra Pilaris Treated with Ustekinumab

Chae MH, Shin JY, Lee JY, Yoon TY

  • KMID: 2440732
  • Korean J Dermatol.
  • 2019 Feb;57(2):101-102.
No abstract available.
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Paradoxical Flare of Psoriasis after Ustekinumab Therapy

Lee HY, Woo CH, Haw S

No abstract available.
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The Phase 3 Trials of Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease

Park SH

No abstract available.
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Multiple Lentigines Arising in Sites of Resolving Psoriatic Plaques after Treatment with Ustekinumab

Kim JS, Lee SK, Ryu HR, Yun CH, Baek JO, Roh JY, Lee JR

No abstract available.
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Squamous Cell Carcinoma Associated with Arsenic Keratosis in a Psoriasis Patient Treated with Ustekinumab: A Case Report

Jung SY

  • KMID: 2391166
  • Korean J Dermatol.
  • 2017 Aug;55(7):440-444.
A 53-year-old Korean woman with known history of psoriasis and treatment with ustekinumab over 16 months, presented with a nontender erythematous plaque with oozing noted on her left sole. Histopathologic...
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Economic Burden Can Be the Major Determining Factor Resulting in Short-Term Intermittent and Repetitive Ustekinumab Treatment for Moderate-to-Severe Psoriasis

Choi CW, Choi JY, Kim BR, Youn SW

BACKGROUND: The continuous use of biologic agents in the treatment of psoriasis has been reported to result in successful and sustained therapeutic effects and safety. However, some patients choose intermittent...
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Erythrodermic Psoriasis Improved by Ustekinumab: A Report of Two Cases

Kim YS, Kim HJ, Lee S, Park YL

No abstract available.
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Economic Factors as Major Determinants of Ustekinumab Drug Survival of Patients with Chronic Plaque Psoriasis in Korea

Choi CW, Yang S, Jo G, Kim BR, Youn SW

BACKGROUND: Drug survival, defined as the time until discontinuation, is a parameter reflecting real-world therapeutic effectiveness. Few studies have examined the influence of economic factors on the drug survival of...
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A Case of Paradoxical Flare of Pustular Psoriasis after Ustekinumab Therapy

Kang IH, Shin MK, Lee MH, Jeong KH

  • KMID: 2436996
  • Korean J Dermatol.
  • 2018 Nov;56(9):548-551.
Biologics are the most advanced treatment for psoriasis. Ustekinumab, one of the biologics for psoriasis, is a human monoclonal antibody that binds to the p40 subunit of interleukin-12 and interleukin-23....
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The Effect of Combination Treatment with Ustekinumab and Topical Agents in Korean Patients with Moderate-to-severe Psoriasis: A Retrospective Study of 30 Patients through 5 Years of Follow Up

Lim J, Woo Y, Kim M, Park HJ

  • KMID: 2373099
  • Korean J Dermatol.
  • 2017 Mar;55(3):171-177.
BACKGROUND: Psoriasis is a chronic inflammatory skin disorder affecting approximately 1~3% of the general population. Ustekinumab is a recently developed human monoclonal antibody for psoriasis that binds to the p40...
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Ustekinumab is effective in biological refractory Crohn's disease patients–regardless of approval study selection criteria

Saman S, Goetz M, Wendler J, Malek NP, Wehkamp J, Klag T

BACKGROUND/AIMS: Ustekinumab is effective in active Crohn's disease. In a retrospective study, we assessed the clinical outcome in nonresponders to anti-tumor necrosis factor therapy, and/or conventional therapy and/or the α4β7-integrin...
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Treatment Outcomes and Response Pattern of Ustekinumab in Korean Patients with Psoriasis: A Retrospective Single-center Study

Oh J, Kim T, Lee MG

  • KMID: 2465951
  • Korean J Dermatol.
  • 2019 Sep;57(8):441-447.
BACKGROUND: Psoriasis is a chronic immune-mediated inflammatory skin disease affecting 2~3% of the worldwide population. Ustekinumab, an IL-12/23p40 inhibitor, is a biologic reported to be effective and safe in treating...
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Efficacy and safety of ustekinumab in Japanese patients with moderately to severely active Crohn's disease: a subpopulation analysis of phase 3 induction and maintenance studies

Hibi T, Imai Y, Murata Y, Matsushima N, Zheng R, Gasink C

BACKGROUND/AIMS: Efficacy and safety of ustekinumab were evaluated in a Japanese subpopulation with moderately to severely active Crohn's disease (CD) in UNITI-1, UNITI-2 and IM-UNITI studies and results were compared...
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Severe Nail Fold Psoriasis Extending from Nail Psoriasis Resolved with Ustekinumab: Suggestion of a Cytokine Overflow Theory in the Nail Unit

Byun SY, Kim BR, Choi JW, Youn SW

Because nail psoriasis is difficult to treat, therapy with many biological drugs has been attempted. Ustekinumab is approved for chronic plaque psoriasis and psoriatic arthritis (PsA), with some trials reporting...
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Severe Refractory Atopic Dermatitis in an Adolescent Patient Successfully Treated with Ustekinumab

Agusti-Mejias A, Messeguer , Garcia R, Febrer I

No abstract available.
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Efficacy and Safety of Ustekinumab in the Treatment of Moderate to Severe Psoriasis in Korea

Park SM, Kim JM, Kim GW, Mun JH, Song M, Kim HS, Ko HC, Kim MB, Kim BS

  • KMID: 2245846
  • Korean J Dermatol.
  • 2015 Sep;53(8):617-622.
BACKGROUND: Ustekinumab, a fully human monoclonal immunoglobulin antibody that targets the P40 subunit shared by interleukin (IL)-12 and IL-23 has emerged as a promising treatment for moderate to severe psoriasis....
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The MARCOPOLO Study of Ustekinumab Utilization and Efficacy in a Real-World Setting: Treatment of Patients with Plaque Psoriasis in Asia-Pacific Countries

Youn SW, Tsai TF, Theng C, Choon SE, Wiryadi BE, Pires A, Tan W, Lee MG, MARCOPOLO Investigators

BACKGROUND: Ustekinumab is a fully human monoclonal antibody approved for the treatment of chronic moderate-to-severe plaque psoriasis in adults. However, factors including efficacy, tolerability, ease of use, and cost burden...
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Efficacy and Safety of Ustekinumab in Korean Patients with Moderate-to-severe Psoriasis

Kim KO, Lee SH, Lee SY, Whang KU, Park YL

  • KMID: 2246084
  • Korean J Dermatol.
  • 2015 Jun;53(5):366-373.
BACKGROUND: Psoriasis is a chronic, relapsing inflammatory disease that affects approximately 2~3% of the population worldwide and often requires lifelong care. Recent advances in understanding the immunogenesis of psoriasis has...
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Appearance of Psoriasis after Tumor Necrosis Factor-alpha Blocker and Use of Ustekinumab or Tocilizumab for Refractory Monoarthritis

Moon J, Kwak N, Lim J, Go DJ, Lee JH, Park JK, Lee EB, Song YW, Youn JI, Lee EY

Nowadays, tumor necrosis factor-alpha (TNF-alpha) blockers are used for treatment of rheumatoid arthritis, inflammatory bowel diseases, ankylosing spondylitis, psoriatic arthritis, and psoriasis. Paradoxically, there are some reports on the appearance...
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The use of biologics for severe psoriasis

Youn SW

Psoriasis is a life-long chronic relapsing dermatosis that shows waxing and waning of disease despite of a lot of conventional treatment. Severe psoriasis, usually defined by a psoriasis area and...
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