Ann Dermatol.  2017 Dec;29(6):794-795. 10.5021/ad.2017.29.6.794.

Paradoxical Flare of Psoriasis after Ustekinumab Therapy

Affiliations
  • 1Department of Dermatology, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea. hawsik@paik.ac.kr

Abstract

No abstract available.


MeSH Terms

Psoriasis*
Ustekinumab*
Ustekinumab

Figure

  • Fig. 1 Before the second ustekinumab injection. Skin lesion was dramatically improved.

  • Fig. 2 (A, B) Paradoxical flare of plaque type psoriasis after the fourth injection.


Reference

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2. Famenini S, Wu JJ. The safety of ustekinumab in psoriasis. J Drugs Dermatol. 2012; 11:907–910.
3. Wenk KS, Claros JM, Ehrlich A. Flare of pustular psoriasis after initiating ustekinumab therapy. J Dermatolog Treat. 2012; 23:212–214.
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4. Hay RA, Pan JY. Paradoxical flare of pustular psoriasis triggered by ustekinumab, which responded to adalimumab therapy. Clin Exp Dermatol. 2014; 39:751–752.
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5. Ko JM, Gottlieb AB, Kerbleski JF. Induction and exacerbation of psoriasis with TNF-blockade therapy: a review and analysis of 127 cases. J Dermatolog Treat. 2009; 20:100–108.
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