- Clinicopathological Features of Rare BRAF Mutations in Korean Thyroid Cancer Patients
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Cho U, Oh WJ, Bae JS, Lee S, Lee YS, Park GS, Lee YS, Jung CK
- KMID: 2129598
- J Korean Med Sci.
- 2014 Aug;29(8):1054-1060.
- doi: 10.3346/jkms.2014.29.8.1054
The most common BRAF mutation in thyroid cancer is c.1799T>A (p.Val600Glu), and other BRAF mutations are rarely reported. We investigated the clinicopathological features of thyroid cancer with rare BRAF mutations.... -
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- Biomarkers for Colorectal Cancer Treatment
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Suk KT, Kim HS
- KMID: 1062808
- Korean J Gastroenterol.
- 2009 Feb;53(2):68-75.
Individualized tailored therapy is a currently pursuing direction for improving the outcome of patients with colorectal cancer. Targeted therapy is the potential strategy to reach this goal by evaluating status... -
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- Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma
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Yu GR, Kim SH, Park SH, Cui XD, Xu DY, Yu HC, Cho BH, Yeom YI, Kim SS, Kim SB, Chu IS, Kim DG
- KMID: 1090967
- Exp Mol Med.
- 2007 Oct;39(5):641-652.
The aim of this study was to identify molecular markers associated with oncogenic differentiation in hepatocellular carcinoma (HCC). Using an unsupervised clustering method with a cDNA microarray, HCC (T) gene... -
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- Pharmacological Unmasking Microarray Approach-Based Discovery of Novel DNA Methylation Markers for Hepatocellular Carcinoma
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Jung N, Won JK, Kim BH, Suh KS, Jang JJ, Kang GH
- KMID: 1421610
- J Korean Med Sci.
- 2012 Jun;27(6):594-604.
- doi: 10.3346/jkms.2012.27.6.594
DNA methylation is one of the main epigenetic mechanisms and hypermethylation of CpG islands at tumor suppressor genes switches off these genes. To find novel DNA methylation markers in hepatocellular... -
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- The Expression of ERCC1, RRM1, and BRCA1 in Breast Cancer According to the Immunohistochemical Phenotypes
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Kim D, Jung W, Koo JS
- KMID: 2157871
- J Korean Med Sci.
- 2011 Mar;26(3):352-359.
- doi: 10.3346/jkms.2011.26.3.352
We studied the expression of BRCA1, ERCC1, and RRM1 which play an important role in DNA repair systems in breast cancer. Immunohistochemical staining for EGFR, BRCA1, ERCC1, and RRM1 were... -
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- Microsatellite instability and its correlation with clinicopathological features in a series of thyroid tumors prevalent in iodine deficient areas
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Vaish M, Mishra A, Kaushal M, Mishra SK, Mittal B
- KMID: 1380206
- Exp Mol Med.
- 2004 Apr;36(2):122-129.
Thyroid tumors display diverse spectrum of histopathological groups with geographic variation in its prevalence. Influence of iodine deficiency (a major causative factor) in its etiology, prevalence, or aggressiveness is debatable... -
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