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Emerging strategies for the treatment of pulmonary tuberculosis: promise and limitations?

Yew WW, Koh WJ

A worsening scenario of drug-resistant tuberculosis has increased the need for new treatment strategies to tackle this worldwide emergency. There is a pressing need to simplify and shorten the current...
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Endobronchial actinomycosis simulating endobronchial tuberculosis: a case report

Lee SH, Shim JJ, Kang EY, Lee SY, Jo JY, In KH, Yoo SH, Kang KH

We report a case of a 70-year-old woman who presented with mild exertional dyspnea and cough. Fiberoptic bronchoscopic findings revealed an endobronchial polypoid lesion with stenotic bronchus. The lesion was...
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Detection of Mycobacterium tuberculosis in clinical samples from patients with tuberculosis or other pulmonary diseases by polymerase chain reaction

Yoon KH, Cho SN, Lee TY, Cheon SH, Chang J, Kim SK, Chong Y, Chung DH, Lee WY, Kim JD

Polymerase chain reaction (PCR) using primers targeting the IS6110 repetitive sequence was employed to detect Mycobacterium tuberculosis in 228 samples from patients with tuberculosis or other pulmonary diseases and controls,...
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Clinical and Bronchoscopic Findings in Ugandans with Pulmonary Kaposi's Sarcoma

Yoo DJ, Lee KH, Munderi P, Shin KC, Lee JK

BACKGROUND: Pulmonary Kaposi's sarcoma (PKS) directly affects the life expectancy of those infected and yet the clinical and radiographic features of Kaposi's sarcoma (KS) with pulmonary involvement are nonspecific, which...
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A Case of Paradoxical Reaction Development during Antituberculosis Therapy

Cho YB, Chu MS, Ryu HS, Choi SC, Seo GS

Paradoxical reaction during antituberculosis therapy is defined as aggravation of preexisting tuberculous lesions or the development of new lesions. A 24-year-old female college student diagnosed with abdominal and pulmonary tuberculosis...
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Drug-resistance pattern of Mycobacterium tuberculosis strains from patients with pulmonary and extrapulmonary tuberculosis during 2006 to 2013 in a Korean tertiary medical center

Lee HY, Lee J, Lee YS, Kim MY, Lee HK, Lee YM, Shin JH, Ko Y

BACKGROUND/AIMS: We evaluated the trend in the rates of drug-resistant tuberculosis (TB) over time, as well as the difference in the drug-resistance pattern between pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis...
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Imatinib mesylate-induced interstitial lung disease in a patient with prior history of Mycobacterium tuberculosis infection

Lee NR, Jang JW, Kim HS, Yhim HY

No abstract available.
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Isolation of Mycobacterium lentiflavum from a Patient with a Lung Destroyed by Tuberculosis

Shin S, Yoon JH, Song SH, Kim EC

Mycobacterium lentiflavum has recently been described as an emerging human pathogen without regard to the immune status of the host. We herein report on M. lentiflavum isolated from a respiratory...
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Description of Pediatric Tuberculosis Evaluated in a Referral Center in Istanbul Turkey

Gulec SG, Telhan L, Kockaya T, Erdem E, Bayraktar , Palanduz A

PURPOSE: Diagnosis of tuberculosis (TB) in children is more challenging than in adults. This study aimed to describe demographical, clinical and laboratory findings of children diagnosed with tuberculosis in Turkey,...
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Is Multi-Drug Resistant Tuberculosis More Prevalent in HIV-Infected Patients in Korea?

Lee S, Lee SH, Mok JH, Lee SJ, Kim KH, Lee JE, Lee SG, Chung JS, Kwak IS

The epidemiological synergy between human immunodeficiency virus (HIV) and tuberculosis (TB) is a major threat to public health. However, the association between HIV and multi-drug resistant tuberculosis (MDR-TB) is not...
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Impact of outdoor air pollution on the incidence of tuberculosis in the Seoul metropolitan area, South Korea

Hwang SS, Kang S, Lee JY, Lee JS, Kim HJ, Han SK, Yim JJ

BACKGROUND/AIMS: Although indoor air pollution is a well-known risk factor for tuberculosis (TB), the possible link between outdoor air pollution and TB development has not been examined fully. We assessed...
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The Incidence and Clinical Implication of Sputum with Positive Acid-Fast Bacilli Smear But Negative in Mycobacterial Culture in a Tertiary Referral Hospital in South Korea

Lee JS, Kim EC, Joo SI, Lee SM, Yoo CG, Kim YW, Han SK, Shim YS, Yim JJ

Although it is not rare to find sputum that is positive acid-fast bacilli (AFB) smear but subsequent culture fails to isolate mycobacteria in clinical practice, the incidence and clinical implication...
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Comparison of AdvanSure TB/NTM PCR and COBAS TaqMan MTB PCR for Detection of Mycobacterium tuberculosis Complex in Routine Clinical Practice

Cho WH, Won EJ, Choi HJ, Kee SJ, Shin JH, Ryang DW, Suh SP

The AdvanSure tuberculosis/non-tuberculous mycobacterium (TB/NTM) PCR (LG Life Science, Korea) and COBAS TaqMan Mycobacterium tuberculosis (MTB) PCR (Roche Diagnostics, USA) are commonly used in clinical microbiology laboratories. We aimed to...
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