- The S-genomic RNA of Hantaan virus contains only two trinucleotide repeats at its 5' end and the 3' end of 3'-specific mRNA is truncated and lacks poly-A tail
-
Dobbs M, Jin MR, Kang CY
- KMID: 2128630
- Exp Mol Med.
- 1997 Mar;29(1):81-83.
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Human FEN-1 can process the 5'-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner
-
Lee SM, Park MS
- KMID: 931883
- Exp Mol Med.
- 2002 Sep;34(4):313-317.
Trinucleotide repeat (TNR) instability can cause a variety of human genetic diseases including myotonic dystrophy and Huntington's disease. Recent genetic data show that instability of the CAG/CTG repeat DNA... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Spinocerebellar Ataxia Type 1 with Atypical Features
-
Koh SH, Yoon OY, Kim J, Kim HT
- KMID: 2342940
- J Korean Neurol Assoc.
- 2001 Sep;19(5):553-554.
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Juvenile Onset Spinocerebellar Ataxia Type 3
-
Kim JS, Kim YI, Lee KS, Jin DK
- KMID: 2329239
- J Korean Child Neurol Soc.
- 2000 Dec;8(2):329-332.
The genetic locus of spinocerebellar ataxia type 3 (SCA3) is linked to chromosome 14q 24.3-qter like Machado-Joseph disease (MJD). The number of CAG repeats on mutant chromosome correlates positively with severity of... -
- CITED
-
- Close
- SHARE
-
- Close
- Trinucleotide Repeats Number in SCA2, SCA3, and SCA17 in Early-Onset Parkinson's Disease
-
Choi JM, Woo MS, Kim S, Ma HI, Sung YH, Lee PH, Chung SJ, Kim JS, Kang SY, Shin HW, Lyoo CH, Sohn YH, Kim JH, Kim JW, Kim SJ, Baik JS, Park MY, Lee MS, Lee MC, Kim YJ
- KMID: 2343305
- J Korean Neurol Assoc.
- 2008 Feb;26(1):23-27.
BACKGROUND: Abnormal expansion of trinucleotide repeats in genes causing spinocerebellar ataxias such as SCA2, SCA3, SCA8, or SCA17 was reported in sporadic or familial Parkinson's disease. Genetic factors play an... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Spinocerebellar Ataxia Type 7 with Torticollis
-
Lee JG, Kim HS, Lee MS
- KMID: 2185774
- J Korean Neurol Assoc.
- 2003 Dec;21(6):663-666.
The spinocerebellar ataxia type 7 is an autosomal dominant neurodegenerative disorder with expansion of unstable CAG trinucleotide repeats in a gene on chromosome 3p, and is classified as autosomal dominant... -
- CITED
-
- Close
- SHARE
-
- Close
- Molecular screening for fragile x syndrome in mentally handicapped children in korea
-
Kwon SH, Lee KS, Hyun MC, Song KE, Kim JK
- KMID: 1129896
- J Korean Med Sci.
- 2001 Jun;16(3):271-275.
- doi: 10.3346/jkms.2001.16.3.271
Fragile X syndrome is one of the most common forms of inherited mental retardation and is caused by the expansion of the CGG trinucleotide repeats in the FMR-1 gene. This... -
- CITED
-
- Close
- SHARE
-
- Close
- No Association between (AAT)n Repeat Polymorphisms in the Cannabinoid Receptor 1 Gene and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia
-
Kim MJ, Kim CR, Park JW, Pak DH, Shin HD, Choi IG, Hahn SW, Hwang J, Lee YJ, Woo SI
- KMID: 2361590
- Korean J Biol Psychiatry.
- 2016 Nov;23(4):148-156.
- doi: 10.0000/kjbp.2016.23.4.148
OBJECTIVES: According to previous studies, the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. Some studies have linked the (AAT)n trinucleotide repeat polymorphism in CNR1... -
- CITED
-
- Close
- SHARE
-
- Close
- Trinucleotide Repeat Polymorphisms of SBMA Locus in Koreans Chinese, Japanese and Caucasoids
-
Lee SB, Goto J, Kanazawa I, Park YH, Hirai M
- KMID: 2283036
- Korean J Phys Anthropol.
- 1997 Dec;10(2):217-223.
SBMA (Spinal bulbar muscular atrophy) is a neurodegenerative disease and the extension of the triplet repeat DNA tracks on this SBMA locus is related with the onset of the genetic... -
- CITED
-
- Close
- SHARE
-
- Close
- A Study on CAG Repeat Polymorphisms of the Androgen Receptor in Korean Androgenetic Alopecia : Preliminary Report
-
Jung JG, Park JW, Kim MH, Cinn YW
- KMID: 2425015
- Korean J Dermatol.
- 2009 Jul;47(7):772-776.
BACKGROUND: The androgen receptor (AR) is a conserved member of the nuclear receptor superfamily. Differences in the AR gene sequence are characterized mostly by a highly polymorphic trinucleotide repeat (CAG)... -
- CITED
-
- Close
- SHARE
-
- Close
- Dentatorubro-pallidoluysian Atrophy: The Clinical and Molecular Genetic Study of Three Korean Families
-
Bae YH, Im JH, Lee SA, Park SS, Lee MC
- KMID: 2342835
- J Korean Neurol Assoc.
- 2000 Jul;18(4):465-468.
Dentatorubro-pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder with various clinical phenotypes and has a cytosine-adenine-guanine (CAG) trinucleotide repeat in a gene on chromosome 12. It has been known that... -
- CITED
-
- Close
- SHARE
-
- Close
- Molecular diagnosis of fragile X syndrome in a female child
-
Jeong SY, Yang JA, Kim HJ
- KMID: 2184446
- J Genet Med.
- 2008 Jun;5(1):41-46.
PURPOSE: Fragile X syndrome (FXS) is the most common heritable cause of cognitive impairment. FXS is caused by hyperexpansion and hypermethylation of a polymorphic CGG trinucleotide repeat in the 5'... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Spinocerebellar Ataxia Type 2
-
Hong S, Lee GH, Yang DW, Lee W, Lee B, Kim JW
- KMID: 2329238
- J Korean Child Neurol Soc.
- 2000 Dec;8(2):324-328.
This is a case of a boy with autosomal dominant cerebellar ataxia (SCA type 2), which was confirmed by DNA analysis. A 9-year-old boy had been suffering from tremor in both arm... -
- CITED
-
- Close
- SHARE
-
- Close
- The CTG Repeat Polymorphisms of Myotonic Dystrophy (DM) Gene in Korean Population
-
Shim SH, Cho YH, Choi SK, Chung SR
- KMID: 1963060
- J Genet Med.
- 1997 Sep;1(1):23-26.
Myotonic dystrophy(DM) is caused by the expansion of CTG trinucleotide repeat near the 3' end of the gene encoding for a member of protein kinase gene family (DMPK). The normal... -
- CITED
-
- Close
- SHARE
-
- Close
- Optimized Methods of Preimplantation Genetic Diagnosis for Trinucleotide Repeat Diseases of Huntington's Disease, Spinocerebellar Ataxia 3 and Fragile X Syndrome
-
Kim MJ, Lee HS, Lim CK, Cho JW, Kim JY, Koong MK, Song IO, Kang IS, Jun JH
- KMID: 1986938
- Korean J Reprod Med.
- 2007 Sep;34(3):179-188.
OBJECTIVES: Many neurological diseases are known to be caused by expansion of trinucleotide repeats (TNRs). It is hard to diagnose the alteration of TNRs with single cell level for preimplantation... -
- CITED
-
- Close
- SHARE
-
- Close
- Analysis of trinucleotide repetitive sequences for Korean patients with spinocerebellar ataxia types 8, 12, and 17
-
Kim GH, Chung SJ, Ryu HS, Kim J, Lee JJ, Choi SH, Lee J, Lee BH, Choi JH, Yoo HW
- KMID: 2055588
- J Genet Med.
- 2015 Jun;12(1):38-43.
- doi: 10.5734/JGM.2015.12.1.38
PURPOSE: Spinocerebellar ataxias (SCAs) are progressive neurodegenerative disorders with diverse modes of inheritance. There are several subtypes of SCAs. SCA 8, SCA 12, and SCA 17 are the less common... -
- CITED
-
- Close
- SHARE
-
- Close
- CAG Repeat Expansions in the Patients with Mood Disorder
-
Sohn SE, Lim SW, Lee SY, Hwang HZ, Jin DK, Park JE, Kim DK, Kim E
- KMID: 2340441
- J Korean Neuropsychiatr Assoc.
- 2000 Mar;39(2):373-380.
OBJECTIVES: The genetic facotrs have been suggested for the etiology of mood disorders but the mode of inheritance is complex. Increased severity and an earlier onset of the bipolar and... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Significance of CTG Repeat Expansion in Korean Myotonic Dystrophy Patients
-
Choi BO, SunWoo IN, Kim SM, Lee JS, Lee EK, Park KD, Jung KH, Moon JS
- KMID: 1905135
- J Korean Neurol Assoc.
- 1999 Jul;17(4):548-553.
BACKGROUND: Myotonic dystrophy is the most common type of muscular dystrophy affecting adults, associated with the expansion of triplet repeat DNA sequences. A hallmark of the inherited disease with trinucleotide... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical characteristics of congenital myotonic dystrophy diagnosed by molecular genetic method
-
Nam SH, Son YB, Lee BL, Lee J, Ki CS, Lee M
- KMID: 2140816
- Korean J Pediatr.
- 2007 Sep;50(9):868-874.
- doi: 10.3345/kjp.2007.50.9.868
PURPOSE: We performed this study to investigate the perinatal and developmental features of the patients with congenital myotonic dystrophy (CDM) confirmed by the molecular genetic method and the clinical characteristics... -
- CITED
-
- Close
- SHARE
-
- Close
- A study of trinucleotide repeat expansions in myotonic dystrophy
-
Jin DK, Kim BJ, Lee KH, Lee MH, Oh PS, Jeon KW, Hwang HZ, Noh HW, Kim SJ, Yeo SH, Yu JS
- KMID: 2342590
- J Korean Neurol Assoc.
- 1997 Feb;15(1):90-98.
PURPOSE: The trinucleotide repeat expansion in the 3' untanslated resion of the gene is known to be the cause of myotonic dystrophy which is one of most common neurodegenerative disorder... -
- CITED
-
- Close
- SHARE
-
- Close
