- p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line
-
Jiang A, Yu C, Zhang P, Chen W, Liu W, Hu X, Zhang J
- KMID: 1115940
- Exp Mol Med.
- 2006 Dec;38(6):625-633.
Prostate cancer is a disease involving complicated multiple-gene alterations. Both NKX3.1 and p53 are related to prostate cancer and play crucial roles in prostate cancer progression. However, little is known... -
- CITED
-
- Close
- SHARE
-
- Close
- Overexpression of SOX9 in mouse embryonic stem cells directs the immediate chondrogenic commitment
-
Kim JH, Do HJ, Yang HM, Oh JH, Choi SJ, Kim DK, Cha KY, Chung HM
- KMID: 1093460
- Exp Mol Med.
- 2005 Aug;37(4):261-268.
Mouse embryonic stem (mES) cells are capable of undergoing chondrogenesis in vitro. To enhance this process, the human SOX9 (hSOX9) cDNA was delivered into mES cells and the clones overexpressing... -
- CITED
-
- Close
- SHARE
-
- Close
- Delayed allograft rejection by the suppression of class II transactivator
-
Kim TW, Choi YM, Seo JN, Kim JH, Suh YH, Chung DH, Jung KC, Oh KI
- KMID: 1094146
- Exp Mol Med.
- 2006 Jun;38(3):210-216.
We examined the effect of class II transactivator (CIITA) down-modulation on allograft rejection. To inhibit the function of CIITA, we constructed a series of CIITA mutants and found one exhibiting... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of a putative transactivation domain in human Nanog
-
Oh JH, Do HJ, Yang HM, Moon SY, Cha KY, Chung HM, Kim JH
- KMID: 1056238
- Exp Mol Med.
- 2005 Jun;37(3):250-254.
Nanog is a newly identified divergent homeodomain protein that directs the infinite propagation and sustains the pluripotency of embryonic stem cells. It has been reported that murine Nanog has two... -
- CITED
-
- Close
- SHARE
-
- Close
- The translation inhibitor anisomycin induces Elk-1-mediated transcriptional activation of egr-1 through multiple mitogen-activated protein kinase pathways
-
Shin SY, Lee JH, Min B, Lee YH
- KMID: 1115946
- Exp Mol Med.
- 2006 Dec;38(6):677-685.
The early growth response-1 gene (egr-1) encodes a zinc-finger transcription factor Egr-1 and is rapidly inducible by a variety of extracellular stimuli. Anisomycin (ANX), a protein synthesis inhibitor, stimulates mitogen-activated... -
- CITED
-
- Close
- SHARE
-
- Close
- Overexpression of neurogenin1 induces neurite outgrowth in F11 neuroblastoma cells
-
Kim SY, Ghil SH, Kim SS, Myeong HH, Lee YD, Suh-Kim HY
- KMID: 1121101
- Exp Mol Med.
- 2002 Dec;34(6):469-475.
Neurogenin1 (Ngn1) is a basic helix-loop-helix (bHLH) transcription factor expressed in neuronal precursors in the developing nervous system. The function of Ngn1 in neurogenesis has been shown in various... -
- CITED
-
- Close
- SHARE
-
- Close
- Acetyl-CoA carboxylase beta expression mediated by MyoD and muscle regulatory factor 4 is differentially affected by retinoic acid receptor and retinoid X receptor
-
Kim JY, Lee JJ, Kim KS
- KMID: 1088654
- Exp Mol Med.
- 2003 Feb;35(1):23-29.
Mammals have two major isoforms of acetyl-CoA carboxyase (ACC). The 275 kDa beta-form (ACC beta) is predominantly in heart and skeletal muscle while the 265 kDa alpha-form (ACC alpha) is... -
- CITED
-
- Close
- SHARE
-
- Close
- American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines
-
Duda RB, Kang SS, Archer SY, Meng S, Hodin RA
- KMID: 1721175
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S54-S60.
- doi: 10.3346/jkms.2001.16.S.S54
American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle... -
- CITED
-
- Close
- SHARE
-
- Close
- Transactivation of peroxisome proliferator-activated receptor alpha by green tea extracts
-
Lee K
- KMID: 1093627
- J Vet Sci.
- 2004 Dec;5(4):325-330.
Tea is a popular beverage. Recently, green tea was reported to increase the number of peroxisomes in rats. In this study, to find out whether the green tea-induced proliferation of... -
- CITED
-
- Close
- SHARE
-
- Close
- Development of ligand-dependent regulatory system and its application to gene therapy of insulin-dependent diabetes mellitus
-
Kim JM, Kim SJ, Lee HC, Kim KS
- KMID: 1110122
- Exp Mol Med.
- 2006 Aug;38(4):385-392.
To develop an inducible expression system, the enhanced artificial nuclear receptors and target reporters were constructed. Artificial nuclear receptors were generated by fusing three domains, consisting of DNA-binding domain (DBD)... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2
-
Kim BE, Lee JH, Kim HS, Kwon OJ, Jeong SW, Kim IK
- KMID: 1123765
- Exp Mol Med.
- 2004 Oct;36(5):444-453.
delta12-Prostaglandin (PG) J2 is known to elicit an anti-neoplastic effects via apoptosis induction. Previous study showed delta12-PGJ2-induced apoptosis utilized caspase cascade through cytochrome c-dependent pathways in HeLa cells. In this... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification and functional characterization of an alternative splice variant within the fourth exon of human nanog
-
Kim JS, Kim J, Kim BS, Chung HY, Lee YY, Park CS, Lee YS, Lee YH, Chung IY
- KMID: 1116205
- Exp Mol Med.
- 2005 Dec;37(6):601-607.
Nanog, a homeodomain (HD) transcription factor, plays a critical role in the maintenance of embryonic stem (ES) cell self-renewal. Here, we report the identification of an alternatively-spliced variant of nanog.... -
- CITED
-
- Close
- SHARE
-
- Close
- Colocalization of Interferon Regulatory Factor 7 (IRF7) with Latent Membrane Protein 1 (LMP1) of Epstein-Barr Virus
-
Kim IW, Park HS
- KMID: 1778415
- J Korean Med Sci.
- 2006 Jun;21(3):379-384.
- doi: 10.3346/jkms.2006.21.3.379
Interferon regulatory factor 7 (IRF7) is one of the transcriptional factors for the activation of type I Interferon (IFN) genes. It is known that IRF7 and the latent membrane protein... -
- CITED
-
- Close
- SHARE
-
- Close
- Deoxycholic Acid-Induced Signal Transduction in HT-29 Cells: Role of NF-kappa B and Interleukin-8
-
Lee DK, Park SY, Baik SK, Kwon SO, Chung JM, Oh ES, Kim HS
- KMID: 772624
- Korean J Gastroenterol.
- 2004 Mar;43(3):176-185.
BACKGROUND/AIMS: Deoxycholic acid (DCA) has been appeared to be an endogenous colon tumor promoter. In this study, we investigated whether DCA induces nuclear factor-kappa B (NF-kappa B) activation and... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of HMGB-1 Overexpression on Cell-Cycle Progression in MCF-7 Cells
-
Yoon S, Lee JY, Yoon BK, Bae DS, Choi DS
- KMID: 1786806
- J Korean Med Sci.
- 2004 Jun;19(3):321-326.
- doi: 10.3346/jkms.2004.19.3.321
High mobility group-1 (HMGB-1) enhances the DNA interactions and possesses a transcriptional activation potential for several families of sequence-specific transcriptional activators. In order to examine the effect of HMGB-1 on... -
- CITED
-
- Close
- SHARE
-
- Close
