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Efficacy of the Erector Spinae Plane Block for Lumbar Spinal Surgery: A Retrospective Study

Ueshima H, Inagaki M, Toyone T, Otake H

STUDY DESIGN: A retrospective study. PURPOSE: The first research on the erector spinae plane (ESP) block was published in 2016. To our knowledge, no cohort studies or randomized controlled trials of...
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Efficacy of the Thoracolumbar Interfascial Plane Block for Lumbar Laminoplasty: A Retrospective Study

Ueshima H, Ozawa T, Toyone T, Otake H

STUDY DESIGN: This paper was a single center-based retrospective study with prospective data collection. PURPOSE: Compared with other surgeries, limited options are available for perioperative pain management in spinal surgery. Therefore,...
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No Acceleration of Intervertebral Disc Degeneration after a Single Injection of Bupivacaine in Young Age Group with Follow-Up of 5 Years

Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Takaso M, Toyone T, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Takahashi

STUDY DESIGN: Prospective study of changes in intervertebral disc degeneration after injection of bupivacaine. PURPOSE: To examine whether injection of bupivacaine into human intervertebral discs accelerates their degeneration. OVERVIEW OF LITERATURE: Bupivacaine...
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Transdermal Fentanyl for Chronic Low Back Pain

Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Aoki Y, Kuniyoshi , Nakamura J, Ishikawa T, Arai G, Miyagi M, Kamoda H, Suzuki M, Toyone T, Takahashi

PURPOSE: Chronic low back pain is a common clinical problem. As medication, non-steroidal anti-inflammatory drugs are generally used; however, they are sometimes non-effective. Recently, opioids have been used for the...
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Interspinous Ligament Lidocaine and Steroid Injections for the Management of Baastrup's Disease: A Case Series

Okada K, Ohtori S, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Toyone T, Yamauchi K, Takahashi

STUDY DESIGN: Prospective study. PURPOSE: To examine the long-term effects of interspinous ligament injections of local anesthetics and steroids for the treatment of Baastrup's diseases. OVERVIEW OF LITERATURE: Baastrup's disease is associated...
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Clinical Incidence of Sacroiliac Joint Arthritis and Pain after Sacropelvic Fixation for Spinal Deformity

Ohtori S, Sainoh T, Takaso M, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Arai G, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Yamazaki M, Toyone T, Takahashi

PURPOSE: Sacroiliac fixation using iliac screws for highly unstable lumbar spine has been reported with an improved fusion rate and clinical results. On the other hand, there is a potential...
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Injection of Bupivacaine into Disc Space to Detect Painful Nonunion after Anterior Lumbar Interbody Fusion (ALIF) Surgery in Patients with Discogenic Low Back Pain

Kimura S, Ohtori S, Orita S, Inoue G, Eguchi Y, Takaso M, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Yamauchi K, Toyone T, Nakamura J, Kishida S, Sato J, Takahashi

  • KMID: 2386481
  • Yonsei Med J.
  • 2014 Mar;55(2):487-492.
PURPOSE: Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery; however, whether the nonunion causes...
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Progressive Change in Joint Degeneration in Patients with Knee or Hip Osteoarthritis Treated with Fentanyl in a Randomized Trial

Fujii T, Takana K, Orita S, Inoue G, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Yamauchi K, Toyone T, Nakamura J, Kishida S, Takahashi , Ohtori S

PURPOSE: Opioids improve pain from knee and hip osteoarthritis (OA) and decrease the functional impairment of patients. However, there is a possibility that opioids induce analgesia and suppress the physiological...
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Increase of TRPV1-Immunoreactivity in Dorsal Root Ganglia Neurons Innervating the Femur in a Rat Model of Osteoporosis

Yoshino K, Suzuki M, Kawarai Y, Sakuma Y, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

PURPOSE: Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, which can be activated by capsaicin and other noxious stimuli. Recently, an association between bone pain and...
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Transient Receptor Potential Vanilloid 1-Immunoreactive Innervation Increases in Fractured Rat Femur

Kawarai Y, Suzuki M, Yoshino K, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Takaso M, Toyone T, Takahashi , Ohtori S

PURPOSE: Pain from vertebral or femoral neck fractures is a particularly important problem in clinical orthopaedics. Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, and there...
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Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Lumbar Spinal Degeneration Disease

Ohtori S, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Toyone T, Inoue G, Takahashi

PURPOSE: Surgery for lumbar spinal degeneration disease is widely performed. While posterior decompression and fusion are popular, anterior lumbar interbody fusion (ALIF) is also used for treatment. Extreme lateral interbody...
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Up-Regulation of Pain Behavior and Glial Activity in the Spinal Cord after Compression and Application of Nucleus Pulposus onto the Sciatic Nerve in Rats

Norimoto M, Sakuma Y, Suzuki M, Orita S, Yamauchi K, Inoue G, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

STUDY DESIGN: Experimental animal study. PURPOSE: To evaluate pain-related behavior and changes in glial activity in the spinal dorsal horn after combined sciatic nerve compression and nucleus pulposus (NP) application in...
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Efficacy of Combination of Meloxicam and Pregabalin for Pain in Knee Osteoarthritis

Ohtori S, Inoue G, Orita S, Takaso M, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Kubota G, Sakuma Y, Oikawa Y, Toyone T, Inage K, Sainoh T, Yamauchi K, Takahashi

PURPOSE: Osteoarthritic pain is largely considered to be inflammatory pain. Sensory nerve fibers innervating the knee have been shown to be significantly damaged in rat models of knee osteoarthritis (OA)...
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Degenerative Lumbar Spondylolisthesis with Spinal Stenosis: A Comparative Study of 5-Year Outcomes Following Decompression with Fusion and Microendoscopic Decompression

Aihara T, Toyone T, Murata Y, Inage K, Urushibara M, Ouchi J

STUDY DESIGN: Retrospective review of prospectively collected outcome data. PURPOSE: To compare 5-year outcomes following decompression with fusion (FU) and microendoscopic decompression (MED) in patients with degenerative lumbar spondylolisthesis (DLS) and...
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Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee

Ohtori S, Orita S, Yamashita , Ishikawa T, Ito T, Shigemura , Nishiyama , Konno S, Ohta H, Takaso M, Inoue G, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Arai G, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Furuya T, Kubota G, Sakuma Y, Oikawa Y, Suzuki M, Sasho T, Nakagawa K, Toyone T, Takahashi

PURPOSE: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction...
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Evaluation of Behavior and Expression of Receptor Activator of Nuclear Factor-Kappa B Ligand in Dorsal Root Ganglia after Sciatic Nerve Compression and Application of Nucleus Pulposus in Rats

Matsuyama , Sakuma Y, Suzuki M, Orita S, Yamauchi K, Inoue G, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

STUDY DESIGN: Experimental animal study. PURPOSE: To evaluate pain-related behavior and changes in nuclear factor-kappa B (NF-kB), receptor activator of NF-kB (RANK), and ligand (RANKL) in dorsal root ganglia (DRG) after...
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Incidence of Nocturnal Leg Cramps in Patients with Lumbar Spinal Stenosis before and after Conservative and Surgical Treatment

Ohtori S, Yamashita , Murata Y, Eguchi Y, Aoki Y, Ataka H, Hirayama J, Ozawa T, Morinaga T, Arai H, Mimura M, Kamoda H, Orita S, Miyagi M, Miyashita , Okamoto Y, Ishikawa T, Sameda H, Kinoshita , Hanaoka E, Suzuki M, Suzuki M, Aihara T, Ito T, Inoue G, Yamagata M, Toyone T, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Yamauchi K, Takahashi , Chiba Low Back Pain Research Group

PURPOSE: To examine the effects of conservative and surgical treatments for nocturnal leg cramps in patients with lumbar spinal stenosis (LSS). Nocturnal leg cramps is frequently observed in patients with...
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Efficacy of Direct Injection of Etanercept into Knee Joints for Pain in Moderate and Severe Knee Osteoarthritis

Ohtori S, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Shiga Y, Abe K, Fujimoto K, Kanamoto H, Toyone T, Inoue G, Takahashi

PURPOSE: Osteoarthritic (OA) pain is largely considered to be inflammatory pain. However, during the last stage of knee OA, sensory nerve fibers in the knee are shown to be significantly...
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Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Degenerated Lumbar Spinal Kyphoscoliosis

Ohtori S, Mannoji C, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Shiga Y, Abe K, Fujimoto K, Kanamoto H, Toyone T, Inoue G, Takahashi

STUDY DESIGN: Prospective case series. PURPOSE: To examine the clinical efficacy of mini-open anterior retroperitoneal lumbar interbody fusion: oblique lateral interbody fusion (OLIF) for degenerated lumbar spinal kyphoscoliosis. OVERVIEW OF LITERATURE: The...
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Modified Open-Door Laminoplasty Using a Ceramic Spacer and Suture Fixation for Cervical Myelopathy

Ozawa T, Toyone T, Shiboi R, Inada K, Oikawa Y, Takahashi , Ohtori S, Inoue G, Miyagi M, Ishikawa T, Shirahata , Kudo Y, Inagaki K

PURPOSE: To introduce a new simple technique using suture anchors and ceramic spacers to stabilize the elevated laminae in open-door cervical laminoplasty. Although ceramic spacers were placed in the opened...
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