- The Concentration of Tobramycin in Cornea and Sclera After Subconjunctival Injection of Liposome-encapsulated Tobramycin in Rabbits
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Kim EK, Kim HB, Lee SC
- KMID: 2122861
- J Korean Ophthalmol Soc.
- 1988 Oct;29(5):809-813.
The authers investigated the effct of liposome encapsulation on the pharmacokinetics of tobramycin after subconjuctival in jnjection in rabbits. Tobramycin was encapsulated into neutral liposomes of phosphatidylcholine and cholesterol. The... -
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- The Effect of the Toxic Reaction of the Retina by Liposome-encapsulated Tobramycin in Normal Rabbits
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Lim SJ, Kim HB
- KMID: 2123060
- J Korean Ophthalmol Soc.
- 1992 Apr;33(4):357-374.
To determine whether liposome-encapsulated tobramycin is less toxic than commercial tobramycin and the threshold dose of liposome-encapsulated tobramycin required to produce toxic reactions when it was injected intravitreally in rabbit,... -
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- Pharmacokinetics of intravitreally injected liposome-encapsulated tobramycin in normal rabbits
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Kim EK, Kim HB
- KMID: 1729577
- Yonsei Med J.
- 1990 Dec;31(4):308-314.
- doi: 10.3349/ymj.1990.31.4.308
Bacterial endophthalmitis, which is a devastating complication of intraocular surgery or eye trauma, has a poor prognosis. Intravitreal injection of antimicrobial agents has become a part of the standard treatment... -
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- The Effect of a Collagen Shield on Concentrations of Tobramycin in Corneas
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Baik JM, Kim KS, Oh JS
- KMID: 2122937
- J Korean Ophthalmol Soc.
- 1990 Feb;31(2):155-159.
Collagen shields made of porcine scleral collagen were immersed in a solution containing tobramycin sulfate(40 mg/ml) for five minutes, then applied to rabbit corneas. One, four and eight hours after... -
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- Comparative Bioavailability and Efficasy of Tobra(R) or Tobrex(R)
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Kim EK, Kim HB, Kim SY
- KMID: 1949286
- J Korean Ophthalmol Soc.
- 1989 Apr;30(2):175-180.
Two topical 0.3% tobramycin ophthalmic solutions, Tobra(R) and Tobrex(R) were tested for their effects on external eyes in rabbits. The authors studied irritation, epithelial toxicity, pH of solutions and antibiotic... -
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- In-Vitro Efficacy of Synergistic Antibiotic Combinations in Multidrug Resistant Pseudomonas Aeruginosa Strains
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Dundar D, Otkun M
- KMID: 1779615
- Yonsei Med J.
- 2010 Jan;51(1):111-116.
- doi: 10.3349/ymj.2010.51.1.111
PURPOSE: Combination antibiotic treatment is preferred in nosocomial infections caused by Pseudomonas aeruginosa (P. aeruginosa). In vitro synergism tests were used to choose the combinations which might be used in... -
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- Concentration of Tobramycin in the Cornea and Sclera After Subconjunctival Injection of Negatively-charged Liposome Encapsulated Tobramycin in Rabbits
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Han SH, Kim EK, Kim HB, Kim HL
- KMID: 2122892
- J Korean Ophthalmol Soc.
- 1989 Feb;30(1):17-22.
Bacterial keratitis is a common ophthalmic disease. Recently, topical and subconjunctival therapy were equally effective in reducing the number of viable bacteria in experimental corneal ulcers. Subconjunctival injection produced high... -
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- Green Nail Syndrome Treated with the Application of Tobramycin Eye Drop
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Bae Y, Lee GM, Sim JH, Lee S, Lee SY, Park YL
- KMID: 2265596
- Ann Dermatol.
- 2014 Aug;26(4):514-516.
- doi: 10.5021/ad.2014.26.4.514
Green nail syndrome (chromonychia) is a nail disorder characterized by onycholysis and green-black discoloration of the nail bed. This condition is often associated with chronic paronychia. Pseudomonas aeruginosa is the... -
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- Clinical Observations and Therapeutic Effect of Rifampin in Shigellosis
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Kim BK, Shin SH, Kwon YD
- KMID: 2042056
- J Korean Pediatr Soc.
- 1982 Jul;25(7):717-722.
This paper presents the clinical, bacteriological assement and therapeutic effect of antimicrobial agents on 106 cases of shigellosis in children who had been treated at pediatric department of Keimyung University... -
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- The Change of the Tobramycin Concentration in Aqueous Humor According to the Administration Routes
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Lee JH, Song WS, Han MS
- KMID: 2337082
- J Korean Ophthalmol Soc.
- 2003 Feb;44(2):410-418.
PURPOSE: To determine the best routes of administration of Tobramycin, the intracameral concentrations was assessed as time progressed after administering identical amounts and concentrations of tobramycin through various methods. METHODS:... -
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- Statistical Analysis of Antimicrobial Susceptibility Tested on Various Clinical Isolates of Bacteria
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Bae EK, Jeon CH, Hong SI, Kim CS
- KMID: 2373880
- Yeungnam Univ J Med.
- 1986 Dec;3(1):185-192.
- doi: 10.12701/yujm.1986.3.1.185
Antimicrobial susceptibility of the bacterial strains isolated from clinical specimens during the period from June, 1983 to June, 1986 in Yeungnam Medical Center was studied and the following results were... -
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- The Antibacterial Activity of Domestic Toipcal Antibiotics II: In Vitro
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Yang JG, Lee JH
- KMID: 2123731
- J Korean Ophthalmol Soc.
- 1997 Feb;38(2):207-213.
To Assess the efficacy of the new domestic topical antibiotic eyedrops, we evaluated in vitro the antimicrobial activity of Ciprus (ciprofloxacin), Ofloxacin (ofloxacin), Tobramycin (tobramycin), and Ecolicin (erythromycin and colistin)... -
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- The Topical Effects of Antibiotics and Aprotinin in Experimental Pseudomonas Ketaititis
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Hong NS, Kim JC, Shyn KH
- KMID: 2123239
- J Korean Ophthalmol Soc.
- 1993 Mar;34(3):181-187.
The effects of the topically applied antibiotics and Aprotinin were evaluated in the experimentally induced pseudomonas aeruginosa keratitis in rabbits. 40 albino rabbits were used for this study and were... -
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- The Effect of Topical Application of Antibiotics on the Cerebral Cortex
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Park KS, Lee YW
- KMID: 2068075
- J Korean Neurosurg Soc.
- 1981 Mar;10(1):39-52.
Several of the newer broad-spectrum, potent antibiotics are currently being used for the treatment of meningitis, ventriculitis, and shunt tract infection. The risk of complications following intrathecal administration of some... -
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- A Case of Comamonas Acidovorans Corneal Ulcer
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Kim JM, Kim DK, Park JM, Yoo JM, Song JK
- KMID: 2126126
- J Korean Ophthalmol Soc.
- 2005 Dec;46(12):2106-2109.
PURPOSE: To report a case of a Comamonas acidovarans corneal ulcer treated with antibiotics in Korea. Comamonas acidovarans corneal ulcer has not been previously reported to our knowledge. METHODS: A... -
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- Infantile and Childhood Shigellosis in Dae Jon area
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Kim SB, Cho KH, Lee DB
- KMID: 2208720
- J Korean Pediatr Soc.
- 1979 May;22(5):366-371.
Clinical and bacteriological studies were made on 37 cases of infantile and childhood shigellosis treated at pediatric department of St. Mary's hospital in Dae Jon from Jan. 1978 to Dec.... -
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- Evaluation of Efficacy of Polygexamethylene biguanide in Experimental Pseudomonas aeruginosa Keratitis
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Chung SK, Lee JY, Hwang DG
- KMID: 2205381
- J Korean Ophthalmol Soc.
- 1998 Nov;39(11):2506-2513.
To evaluate the efficacy of polygexamethylene biguanide(PHMB) in Pseudomonas aeruginosa(P. aeruginosa) keratites model, 10microliter of P. aeruginosa bacterial suspension(1x103 colony-forming unit(cfu)/ml) was injected intrastromally into rabbit corneas. Eighteen rabbits(36 eyes)... -
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- Comparison of Normal Bacterial Flora in the Conjuntival Sac of Normal and Anophthalmic Eyes
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Choi S, Shin D
- KMID: 2022990
- J Korean Ophthalmol Soc.
- 1991 Nov;32(11):939-943.
A bacterial study of the conjunctival sac of 115 patients with an anophthalmic eye has compared the kinds of normal flora in the conjunctival sac of normal and anophthalmic eyes... -
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- Corneal Tobramycin Levels by Topical Administration of Fortified Tobramycin Solutions in Rabbits
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Chung I, Kim HB, Kim EK, Lee CK
- KMID: 1949108
- J Korean Ophthalmol Soc.
- 1987 Feb;28(1):23-29.
Bacterial keratitis is a common ophthalmic disease. In certain cases of pseudomonas keratitis, the corneal perforation may occur within 24-48 hours of the onset. Soa suitable, massive antibiotic should be... -
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- Antibiotic loaded Plaster of Paris as a Prevention of Experimental Osteomyelitis in Rats
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Lee CJ, Cho WH, Chang SK, Chang HG, Kim JH
- KMID: 2445422
- J Korean Orthop Assoc.
- 1989 Oct;24(5):1479-1485.
- doi: 10.4055/jkoa.1989.24.5.1479
Plaster of Paris is an effective ancillary treatment in the surgery of infected cavities in bone. It is well tolerated and spontaneously absorbed over the period of weeks to months,... -
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