- Strategies for Constructing Tissue-Engineered Fat for Soft Tissue Regeneration
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Zhao J, Lu F, Dong Z
- KMID: 2554990
- Tissue Eng Regen Med.
- 2024 Apr;21(3):395-408.
- doi: 10.1007/s13770-023-00607-z
BACKGROUND: Repairing soft tissue defects caused by inflammation, tumors, and trauma remains a major challenge for surgeons. Adipose tissue engineering (ATE) provides a promising way to solve this problem. METHODS: This... -
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- Advancements in Human Embryonic Stem Cell Research: Clinical Applications and Ethical Issues
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Park SJ, Kim YY, Han JY, Kim SW, Kim H, Ku SY
- KMID: 2554998
- Tissue Eng Regen Med.
- 2024 Apr;21(3):379-394.
- doi: 10.1007/s13770-024-00627-3
BACKGROUND: The development and use of human embryonic stem cells (hESCs) in regenerative medicine have been revolutionary, offering significant advancements in treating various diseases. These pluripotent cells, derived from early... -
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- Modulation of Inflammatory Responses to Enhance Nerve Recovery after Spinal Cord Injury
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Seo YK
- KMID: 2554999
- Tissue Eng Regen Med.
- 2024 Apr;21(3):367-368.
- doi: 10.1007/s13770-024-00639-z
Inflammation can occur at the wound site, and immune cells are necessary to trigger wound healing and tissue regeneration after injury. It is partly initiated by the rapid migration of... -
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- Efficacy of IFN-γ-Primed Umbilical Cord-Derived Mesenchymal Stem Cells on Temporomandibular Joint Osteoarthritis
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Kim H, Kim Y, Yun SY, Lee BK
- KMID: 2554996
- Tissue Eng Regen Med.
- 2024 Apr;21(3):473-486.
- doi: 10.1007/s13770-023-00620-2
BACKGROUND: Temporomandibular joint osteoarthritis (TMJOA) is a degenerative disease affecting the cartilage and subchondral bone, leading to temporomandibular joint pain and dysfunction. The complex nature of TMJOA warrants effective alternative... -
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- α-Gal Nanoparticles in CNS Trauma: I. In Vitro Activation of Microglia Towards a Pro-Healing State
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Gopalakrishnan B, Galili U, Dunbar A, Solorio L, Shi R, Li J
- KMID: 2554992
- Tissue Eng Regen Med.
- 2024 Apr;21(3):409-419.
- doi: 10.1007/s13770-023-00613-1
BACKGROUND: Macrophages and microglia play critical roles after spinal cord injury (SCI), with the pro-healing, antiinflammatory (M2) subtype being implicated in tissue repair. We hypothesize that promoting this phenotype within... -
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- Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing
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Li G, Wang Q, Liu H, Yang Z, Wu Y, He L, Deng X
- KMID: 2554993
- Tissue Eng Regen Med.
- 2024 Apr;21(3):421-435.
- doi: 10.1007/s13770-023-00614-0
BACKGROUND: Insufficient angiogenesis and the lack of skin appendages are critical challenges in cutaneous wound healing. Stem cell-fabricated cell sheets have become a promising strategy, but cell sheets constructed by... -
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- Exosomes Secreted During Myogenic Differentiation of Human Fetal Cartilage-Derived Progenitor Cells Promote Skeletal Muscle Regeneration through miR-145-5p
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Shin DI, Jin YJ, Noh S, Yun HW, Park DY, Min BH
- KMID: 2554995
- Tissue Eng Regen Med.
- 2024 Apr;21(3):487-497.
- doi: 10.1007/s13770-023-00618-w
BACKGROUND: Currently, there is no apparent treatment for sarcopenia, which is characterized by diminished myoblast function. We aimed to manufacture exosomes that retain the myogenic differentiation capacity of human fetal... -
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- Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
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Jäger J, Vahav I, Thon M, Waaijman T, Spanhaak B, Kok Md, Bhogal RK, Gibbs S, Koning JJ
- KMID: 2554997
- Tissue Eng Regen Med.
- 2024 Apr;21(3):499-511.
- doi: 10.1007/s13770-023-00621-1
BACKGROUND: Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, reconstructed human skin (RhS) models lack the metabolic potential of native... -
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- α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes
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Gopalakrishnan B, Galili U, Saenger M, Burket NJ, Koss W, Lokender MS, Wolfe KM, Husak SJ, Stark CJ, Solorio L, Cox A, Dunbar A, Shi R, Li J
- KMID: 2554994
- Tissue Eng Regen Med.
- 2024 Apr;21(3):437-453.
- doi: 10.1007/s13770-023-00616-y
BACKGROUND: Previous investigations have shown that local application of nanoparticles presenting the carbohydrate moiety galactose-a-1,3-galactose (α-gal epitopes) enhance wound healing by activating the complement system and recruiting pro-healing macrophages to... -
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- An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function
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Morrison AI, Mikula AM, Spiekstra SW, Kok Md, Affandi AJ, Roest HP, Laan LJWvd, Winde CMd, Koning JJ, Gibbs S, Mebius RE
- KMID: 2554991
- Tissue Eng Regen Med.
- 2024 Apr;21(3):455-471.
- doi: 10.1007/s13770-023-00609-x
BACKGROUND: Human lymph node (HuLN) models have emerged with invaluable potential for immunological research and therapeutic application given their fundamental role in human health and disease. While fibroblastic reticular cells... -
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