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Effect of Hydrocortisone Succinate on Ca45 Resorption and Incorporation in Bone Culture of Rat

Cho MY, Choi CD, Kim JH

  • KMID: 2439773
  • Yonsei Med J.
  • 1973 Dec;14(1):44-48.
Ca45 resorption and incoporration into albino rat-bones in tissue culture was considered in studying the pathogenesis of osteoporosiscaused by cotinued administration of glucocorticoid, hydrocortisone succinate. 18-day old tibias were cultured...
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"Senility and Death of Tissues Are Not a Necessary Phenomenon": Alexis Carrel and the Origins of Gerontology

Park HW

  • KMID: 1379364
  • Korean J Med Hist.
  • 2011 Jun;20(1):181-208.
The French surgeon and Nobel laureate Alexis Carrel's tissue culture has been highly influential in biomedicine. This paper contextualizes Carrel's works with respect to the birth of gerontology during the...
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Usefulness of Skin Explants for Histologic Analysis after Fractional Photothermolysis

Park GH, Chang SE, Bang S, Won KH, Won CH, Lee MW, Choi JH, Moon KC

BACKGROUND: Fractional laser resurfacing treatment has been extensively investigated and is widely used. However, the mechanism underlying its effects is poorly understood because of the ethical and cosmetic problems of...
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Continuous Cultivation of Fibroblast-type Cells Derived from Rabbit Embryos

Yang YT, Lew J

A line of fibroblast-type cells derived from embryos of a domestic rabbit has been cultivated continuously for over 3 years by serial passages up to the level of the moth...
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IgE production from the nasal polyp tissue: comparison between atopic and non-atopic subjects

Kim HY, Nahm DH, Suh KS, Park HS

  • KMID: 759075
  • Korean J Intern Med.
  • 1998 Jul;13(2):83-87.
OBJECTIVES AND METHODS: To confirm the local production of IgE antibody from the nasal polyp tissue, and to evaluate the difference between atopics and non-atopics, nasal polyp tissues were taken...
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Mechanism of Neuronal Migration in Human Foetal Cerebrum In-vitro

Choi BH

Active migration of immature neurons occurs when fragments of human foetal cerebral tissues are explanted as organotypic cultures. The sequence of events during neuronal migration is orderly and consistent under...
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Fatty Acid Composition of Tissue Cultured Breast Carcinoma and the Effect of Stearoyl-CoA Desaturase 1 Inhibition

Mohammadzadeh F, Mosayebi G, Montazeri , Darabi M, Fayezi S, Shaaker M, Rahmati M, Baradaran , Mehdizadeh A, Darabi M

  • KMID: 2353068
  • J Breast Cancer.
  • 2014 Jun;17(2):136-142.
PURPOSE: Stearoyl-CoA desaturase 1 (SCD1) is a novel therapeutic target in various malignancies, including breast cancer. The present study was designed to investigate the effect of the pharmacologic inhibition of...
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Mycobacterium lepraemurium in Cultured Mouse Peritoneal Macrophage: A Preliminary Report

Yang YT, Lew J

Efforts have been made to accomplish a long term in vitro cultivation of mouse peritoneal macrophage as a host cell for growth of Mycobacterium lepraemurium. Following the inoculation with live...
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Suppression of NF-kappaB activation in normal T cells by supernatant fluid from human renal cell carcinomas

Kim HJ, Park JK, Kim YG

T lymphocytes from patients with renal cell carcinoma (RCC) show reduced immune function and impaired activation of the transcription factor, NF-kappaB. We determined the mechanism of NF-kappaB suppression in T...
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Calpain inhibitors reduce the cornified cell envelope formation by inhibiting proteolytic processing of transglutaminase 1

Kim SY, Bae CD

  • KMID: 755018
  • Exp Mol Med.
  • 1998 Dec;30(4):257-262.
Calpain I (mu-calpain) and II (m-calpain) are well known calcium-activated neutral cysteine proteases. Many reports have shown that activation of calpain is related to cataract formation, neuronal degeneration, blood clotting, ...
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Abnormal ventricular looping and abnormal laterality of the atrial chambers are the main morphogenetic mechanisms of cardiac lesions in cultured rat embryos treated with retinoic acid

Lee YM, Kim JS, Han SY, Park KL, Jang SJ, Seo JW

To establish the early morphogenetic mechanism in retinoid induced cardiac lesions, we investigated the morphology of the heart in cultured rat embryos treated with retinoic acid (RA) at 9.0...
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Chemoprevention of Mammary, Cervix and Nervous system Carcinogenesis in Animals using Cultured Panax ginseng Drugs and Preliminary Clinical Trials in Patients with Precancerous Lesions of the Esophagus and Endometrium

Bespalov V, Alexandrov VA, Limarenko , Voytenkov , Okulov VB, Kabulov MK, Peresunko , Slepyan LI, Davydov VV

The anticarcinogenic effects and mechanisms of the biotechnological drugs of Panax ginseng C.A. Meyer cultivated in Russia, bioginseng, panaxel and panaxel- 5, were studied. Bioginseng was produced from a tissue...
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Fra-1 Expression in Malignant and Benign Thyroid Tumor

Kim YH, Oh JH, Kim NH, Choi KM, Kim SJ, Baik SH, Choi DS, Lee ES

  • KMID: 938273
  • Korean J Intern Med.
  • 2001 Jun;16(2):93-97.
BACKGROUND: The differential diagnosis of thyroid nodules is very important in deciding the treatment modality and the fine needle aspiration is the best diagnostic method. But, there are some...
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Ultrastructural changes of hepatic stellate cells in the space of Disse in alcoholic fatty liver

Han NI, Chung KW, Ahn BM, Choi SW, Lee YS, Lee CD, Sun HS

  • KMID: 759554
  • Korean J Intern Med.
  • 2001 Sep;16(3):160-166.
BACKGROUND: Hepatic stellate cell (HSC) has been suggested to play a role in fibrogenesis in alcoholic liver disease. We evaluate the correlation with fibrogenesis and ultrastructure of hepatic stellate cells...
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Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver

Park CK, Park TR, Kim YB, Kim HY, Yoo JY, Kim CH, Choo SH, Cho JM

  • KMID: 1038874
  • Korean J Intern Med.
  • 1997 Jan;12(1):28-33.
OBJECTIVES: Numerous epidemiologic data have documented that chronic infection by hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC). But the molecular mechanism...
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Netrin Inhibits Regenerative Axon Growth of Adult Dorsal Root Ganglion Neurons in Vitro

Park JI, Seo IA, Lee HK, Park HT, Shin SW, Park YM, Ahn KJ

Netrin is a neuronal guidance molecule implicated in the development of spinal commissural neurons and cortical neurons. The attractive function of netrin requires the receptor, Deleted in Colorectal Cancer (DCC),...
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Differences in immunophenotyping of mucosal lymphocytes between ulcerative colitis and Crohn's disease

Lee HB, Kim JH, Yim CY, Kim DG, Ahn DS

  • KMID: 1038877
  • Korean J Intern Med.
  • 1997 Jan;12(1):7-15.
OBJECTIVES: Immunologic studies have characterized the numbers and types of inflammatory cells in diseased inflammatory bowel disease (IBD) mucosa but have yielded conflicting results regarding intestinal lymphocytes activation in IBD. ...
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Relevance of vacA Genotypes of Helicobacter pylori to cagA Status and Its Clinical Outcome

Park SM, Park J, Kim JG, Yoo BC

  • KMID: 759528
  • Korean J Intern Med.
  • 2001 Mar;16(1):8-13.
BACKGROUND: Determination of vacA mosaicism may be important because specific Helicobacter pylori vacA genotype can be used to predict different clinical outcome. The aim of this study was to assess...
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Influence of 17-alpha-estradiol on catecholamine secretion from the perfused rat adrenal gland

Park YH, Cho GS, Cho ET, Park YK, Lee MJ, Chung JY, Hong SP, Lee JJ, Jang Y, Yoo HJ, Choi CH, Lim DY

  • KMID: 1038461
  • Korean J Intern Med.
  • 1996 Jan;11(1):25-39.
OBJECTIVES: It has been known that adrenal corticosteroids influence the expression of adrenomedullary catecholamine-synthetizing enzymes and also suppress the emission of axonal-like processes in cultured chromaffin cells. In the present...
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