- Thrombopoietin
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Hong DS
- KMID: 1551282
- Korean J Med.
- 1999 Oct;57(4):449-452.
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- Thrombopoietin: a novel candidate tumor marker for the diagnosis of ovarian cancer
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Mermer T, Terek MC, Zeybek B, Ergenoglu , Yeniel AO, Ozsaran A, Zekioglu O
- KMID: 2177580
- J Gynecol Oncol.
- 2012 Apr;23(2):86-90.
- doi: 10.3802/jgo.2012.23.2.86
OBJECTIVE: To investigate the decisive role of preoperative serum thrombopoietin levels in the discrimination of benign and malignant ovarian pathologies and its value in the evaluation of treatment response. METHODS: Fifty... -
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- Effects of Korean Traditional Medicine on Murine Hematopoiesis (1) - Regulation of Hematopoietic Cytokine Expression -
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Kim SH, Lim JS
- KMID: 1550788
- Korean J Immunol.
- 1999 Jun;21(2):165-174.
The Korean traditional medicinal (KTM) herbs such as Angelicae gigantis, Rehmannia glutinosa, Paeoniae lactiflora, Cnidii officinale, Salviae miltiorrhizae, and Millettia reticulata, and prescribed formula Samultang, and Bohyultang improve the function... -
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- Gene Expression Analysis of Megakaryocytes Derived from Human Umbilical Cord CD34(+) Cells by Thrombopoietin
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Kim JA, Kim HL
- KMID: 1572613
- Genomics Inform.
- 2005 Mar;3(1):8-14.
Although much is known about the molecular biology of platelets, the megakaryocytes' (MKs) molecular biology was not understood so well because of their rareness. By the cloning and characterization of... -
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- Characterization of CD34 Positive Cord Blood Cells and Ex-vivo Effects of Thrombopoietin on the Expansion of Human Umbilical Cord Blood
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Lee WI, Choi YM, Suh JT, Lee HJ
- KMID: 2300517
- Korean J Clin Pathol.
- 1999 Feb;19(1):118-124.
BACKGROUND: Umbilical cord blood (UCB) cells are an alternative source of hemopoietic stem cells for transplantation. However, the use of UCB is limited by the lack of number of hemopoietic... -
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- Change of Platelet Count and Mean Platelet Volume after Intravenous Immunoglobulin Injection in Acute Idiopathic Thrombocytopenic Purpura
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Jeon IS, Kim JS, Im HJ
- KMID: 2037382
- Korean J Pediatr Hematol Oncol.
- 2004 Apr;11(1):1-6.
PURPOSE: The platelet synthesis is extremely variable after intravenous immunoglogulin injection (IVIG) in acute idiopathic thrombocytopenic purpura (ITP). To investigate the size variation of platelet according to the time sequence... -
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- Megakaryocytic Differentiation of Human Cord Blood CD34+Cells During ex vivo Expansion
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Kwon SY, Chung WS, Seoh JY
- KMID: 1832118
- Korean J Hematol.
- 2001 May;36(2):136-147.
BACKGROUND: Thrombopoietin (TPO) has been currently used for ex vivo expansion of hematopoietic progenitor cells. Previously, we have reported that TPO induces a characteristic pattern of apoptosis during ex vivo... -
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- Straightforward Identification of Masked Polycythemia Vera Based on Proposed Revision of World Health Organization Diagnostic Criteria for BCR-ABL1-Negative Myeloproliferative Neoplasms
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Chu D, Cho YU, Jang S, Seo EJ, Park CJ
- KMID: 2363272
- Ann Lab Med.
- 2015 Nov;35(6):651-653.
- doi: 10.3343/alm.2015.35.6.651
No abstract available. -
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- The Significance of Serum Thrombopoietin Levels in Cirrhotic Patients with Thrombocytopenia According to Disease Severity
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Yeon JE, Kong W, Kim JH, Suh YS, Park SH, Kwon OS, Byun KS, Lee CH
- KMID: 2241312
- Korean J Hepatol.
- 1999 Sep;5(3):208-216.
BACKGROUND/AIMS: Thrombopoietin (TPO) is an important cytokine for megakaryocyte maturation and platelet production. Because the main site of its production is liver, the failing liver may have a role in thrombocytopenia in... -
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- Relationship between Thrombocytopenia and Serum Thromobopoietin Concentration in Patients with Chronic Liver Diseases
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Cho YK, Kim BI, Koo ES, Kim SY, Kim CS, Park CY, Sohn CI, Jeon WK, Jung ES, Lee SH, Lee DH
- KMID: 1606578
- Korean J Gastroenterol.
- 2002 Feb;39(2):108-113.
BACKGROUND/AIMS: The major origin of thrombocytopenia in liver cirrhosis is attributed to enlarged spleen. In order to determine the influence of thromboprotein (TPO) on the origin of thrombocytopenia in liver... -
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- The Analysis of Thrombopoietin and Clinical Parameters as a Marker for Disease Progression in Patients with Multiple Myeloma
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Lee JJ, Kang SY, Lee WI
- KMID: 1781599
- Korean J Lab Med.
- 2009 Feb;29(1):82-88.
- doi: 10.3343/kjlm.2009.29.1.82
BACKGROUND: Multiple myeloma (MM) causes the suppression of hematopoiesis because of malignant cells in the bone marrow. Thrombopoietin (TPO) is regulated by a feedback mechanism with platelets. Recently, it was... -
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- Stem Cell Factor Inhibits Premature Senescence of Megakaryocytes during ex vivo Expansion of Human Cord Blood CD34+ Cells Using Thrombopoietin
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Ryu KH, Seoh JY, Chung WS, Kie JH, Shin HY, Ahn HS
- KMID: 2037433
- Korean J Pediatr Hematol Oncol.
- 2000 Oct;7(2):212-223.
PURPOSE: Thrombopoietin (TPO) has been currently used for ex vivo expansion of hematopoietic stem cells. Previously, we have reported that TPO induces apoptosis during ex vivo expansion of cord... -
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- Thrombopoietin Level and Bone Marrow Megakaryocyte Colony Formation in Various Diseases with Thrombocytopenia
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Cho JS, Choe BK, Cho YJ, Kim HS, Kang CM
- KMID: 2037432
- Korean J Pediatr Hematol Oncol.
- 2000 Oct;7(2):203-211.
PURPOSE: Thrombocytopenia is a serious life threatening consequence in patients with bone marrow failure syndrome. Thrombopoietin (TPO), recently cloned by several groups has been shown to be a key... -
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- Clinical Significance of Thrombopoietin Levels in Maintenance Hemodialysis Patients with Thrombocytopenia
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Yu JM, Kim JS, Choi JU, Han BG, Choi SO, Lee JI, Uh Y
- KMID: 2254311
- Korean J Nephrol.
- 2004 Jul;23(4):586-592.
BACKGROUND: Thrombopoietin (TPO) is a major cytokine which plays a critical role in the regulation of thrombopoiesis and megakaryopoiesis. Since the kidney is one of the TPO-producing organs, it is... -
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- In Vitro Effect of Interleukin-11 (IL-11) on Megakaryopoiesis from Umbilical Cord Blood Cells
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Lee KK, Kim CK, Lee NS, Kim SJ, Cheong HJ, Lee KT, Park SK, Baick SH, Won JH, Hong DS, Park HS
- KMID: 2167970
- Immune Netw.
- 2003 Mar;3(1):47-52.
- doi: 10.4110/in.2003.3.1.47
BACKGROUND: The megakaryopoiesis and platelet production is regulated by several hematopoietc factors such as thrombopoietin (TPO), interleukin-11 (IL-11) and interleukin-3 (IL-3). IL-11 is a potent stimulator of megakaryopoiesis in vivo,... -
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- Tocilizumab-induced Thrombocytopenia in Patients with Rheumatoid Arthritis
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Lee JS, Oh JS, Hong S, Lee CK, Yoo B, Kim YG
- KMID: 2451510
- J Rheum Dis.
- 2019 Jul;26(3):186-190.
- doi: 10.4078/jrd.2019.26.3.186
OBJECTIVE: Interlukin-6 (IL-6) increases platelet count during inflammation and may act in a manner similar to thrombopoietin. Tocilizumab is a monoclonal antibody of the IL-6 receptor and widely used in... -
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- The Effect of Recombinant Fibronectin Fragment (Retronectin) and Cytokines during deltaLNGFR Retroviral Transduction of CD34+ Cells
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Lee S, Min YH, Ko YW
- KMID: 1533970
- Korean J Hematol.
- 1999 Nov;34(4):534-548.
BACKGROUND: Hematopoietic stem cells (HSC) remain one of the most promising target cells for gene therapeutic approaches, but is currently limited by a number of issues, including the low gene... -
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- Preparation and Characterization of SDF-1alpha Recombinant Adenovirus for ex vivo Expansion of Hematopoietic Stem Cells
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Joo EK, Jo DY, Joo JH, Myung PK, Lee Y
- KMID: 2168480
- J Bacteriol Virol.
- 2005 Mar;35(1):39-47.
Stromal cell-derived factor 1 (SDF-1/CXCL12) is a multifunctional cytokine implicated in normal hematopoiesis. We previously reported that SDF-1alpha enhanced the survival of hematopoietic stem and progenitor cells in synergy with... -
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- Efficacy and safety of eltrombopag in adult refractory immune thrombocytopenia
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Kim YK, Lee SS, Jeong SH, Ahn JS, Yang DH, Lee JJ, Kim HJ
- KMID: 1787908
- Blood Res.
- 2015 Mar;50(1):19-25.
- doi: 10.5045/br.2015.50.1.19
BACKGROUND: Eltrombopag is a thrombopoietin receptor agonist with excellent treatment outcomes in immune thrombocytopenia (ITP). Here, we analyzed the dose of eltrombopag required to achieve and maintain safe platelet counts... -
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- Differences in Hematological and Clinical Features Between Essential Thrombocythemia Cases With JAK2- or CALR-Mutations
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Kubuki Y, Shide K, Kameda T, Yamaji T, Sekine M, Kamiunten , Akizuki K, Shimoda H, Tahira Y, Nakamura K, Abe H, Miike T, Iwakiri H, Tahara Y, Sueta M, Hashimoto , Yamamoto S, Hasuike S, Hidaka T, Nagata K, Kitanaka A, Shimoda K
- KMID: 2373635
- Ann Lab Med.
- 2017 Mar;37(2):159-161.
- doi: 10.3343/alm.2017.37.2.159
No abstract available. -
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