- Inhibitory effects of Sargassum horneri extract against endoplasmic reticulum stress in HepG2 cells
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Park S, Thomas SS, Cha YS, Kim KA
- KMID: 2510206
- J Nutr Health.
- 2020 Dec;53(6):583-595.
- doi: 10.4163/jnh.2020.53.6.583
Purpose: This study examined the effects of Sargassum horneri extracts on palmitic acid (PA)-induced endoplasmic reticulum (ER) stress in HepG2 cells. Methods: HepG2 cells were treated with varying concentrations of S.... -
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- Emodin exerts protective effect against palmitic acid-induced endoplasmic reticulum stress in HepG2 cells
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Thomas SS, Park S, Cha YS, Kim KA
- KMID: 2444941
- J Nutr Health.
- 2019 Apr;52(2):176-184.
- doi: 10.4163/jnh.2019.52.2.176
PURPOSE: Protein overloading in the endoplasmic reticulum (ER) leads to endoplasmic reticulum stress, which exacerbates various disease conditions. Emodin, an anthraquinone compound, is known to have several health benefits. The... -
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- Effect of vegetable oils with different fatty acid composition on high-fat dietinduced obesity and colon inflammation
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Thomas SS, Cha YS, Kim KA
- KMID: 2506881
- Nutr Res Pract.
- 2020 Oct;14(5):425-437.
- doi: 10.4162/nrp.2020.14.5.425
BACKGROUND/OBJECTIVES: Different fatty acids exert different health benefits. This study investigated the potential protective effects of perilla, olive, and safflower oils on high-fat diet-induced obesity and colon inflammation. MATERIALS/METHODS: Five-week old,... -
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- Inhibitory effect of ethanolic extract of Abeliophyllum distichum leaf on 3T3–L1 adipocyte differentiation
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Thomas SS, Eom J, Sung NY, Kim DS, Cha YS, Kim KA
- KMID: 2520658
- Nutr Res Pract.
- 2021 Oct;15(5):555-567.
- doi: 10.4162/nrp.2021.15.5.555
BACKGROUND/OBJECTIVES: Abeliophyllum distichum is a plant endemic to Korea, containing several beneficial natural compounds. This study investigated the effect of A. distichum leaf extract (ALE) on adipocyte differentiation. MATERIALS/METHODS: The cytotoxic... -
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- Green perilla leaf extract ameliorates long-term oxidative stress induced by a high-fat diet in aging mice
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Edward OC, Thomas SS, Cha KO, Jung HA, Han A, Cha YS
- KMID: 2534115
- Nutr Res Pract.
- 2022 Oct;16(5):549-564.
- doi: 10.4162/nrp.2022.16.5.549
BACKGROUND/OBJECTIVES: Oxidative stress is caused by an imbalance between harmful free radicals and antioxidants. Long-term oxidative stress can lead to an “exhausted” status of antioxidant defense system triggering development of... -
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