- Gene expression of surfactant proteins in thiourea treated rate
-
Koh Y, Park SS, Lee JH
- KMID: 1698222
- Korean J Intern Med.
- 1992 Oct;43(4):545-554.
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Simple Method of Preparation and Characterization of New Antifungal Active Biginelli Type Heterocyclic Compounds
-
Pothiraj C, Velan AS, Joseph J, Raman N
- KMID: 2052891
- Mycobiology.
- 2008 Mar;36(1):66-69.
- doi: 10.4489/MYCO.2008.36.1.066
A simple, efficient and cost effective method is described for the synthesis of Biginelli type heterocyclic compounds of dihydropyrimidinones analogous. They were prepared from a reaction mixture consisting of substituted... -
- CITED
-
- Close
- SHARE
-
- Close
- Gene Expression of Surfactant Protein B and C in Endotoxin and Thiourea Treated Rats
-
Sohn DH, Sohn JW, Yoon HJ, Shin DH, Park SS
- KMID: 2158843
- Tuberc Respir Dis.
- 2003 May;54(5):510-521.
- doi: 10.4046/trd.2003.54.5.510
BACKGROUND: The surfactant specific proteins, SP-B and SP-C are believed to be important regulators of the surfactant function and homeostasis. Since acute respiratory distress syndrome(ARDS) is usually viewed as the... -
- CITED
-
- Close
- SHARE
-
- Close
- Gene Expression of Surfactant Protein A mRNA of the Lung in Endotoxin and Thiourea Treated Rats
-
Lee JY, Kim MO, Sohn JW, Yoon HJ, Shin DH, Kim TW, Park SS
- KMID: 2318421
- Tuberc Respir Dis.
- 2003 Sep;55(3):257-266.
BACKGROUND: The surfactant protein A(SP-A) is important in the regulation of surfactant secretion, synthesis and recycling. Since the acute respiratory distress syndrome(ARDS) is usually viewed as the functional and morphological... -
- CITED
-
- Close
- SHARE
-
- Close
- Cytotoxic Activity and Structure Activity Relationship of Ceramide Analogues in Caki-2 and HL-60 Cells
-
Kim YJ, Kim EA, Sohn UD, Yim CB, Im C
- KMID: 2071718
- Korean J Physiol Pharmacol.
- 2010 Dec;14(6):441-447.
- doi: 10.4196/kjpp.2010.14.6.441
B13, a ceramide analogue, is a ceramidase inhibitor and induces apoptosis to give potent anticancer activity. A series of thiourea B13 analogues was evaluated for their in vitro cytotoxic activities... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Methimazole Induced Agranulocytosis Complicated with Deep Neck Abscess
-
Lee KW, Lee SK, Chung YS, Kim HM, Kim YJ, Hong EK, Chae BN, Lee JH, Ha CY, Park JS
- KMID: 1944220
- J Korean Soc Endocrinol.
- 1998 Dec;13(4):617-621.
The thiourea derivatives, propylthiouracil and methimazole are in widespread use for the treatment of hyperthyroidism. The untoward side effects of these drugs are not infrequent and agranulocytosis is the most... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibitory Effect of SPA0355, a Thiourea Analogue, on Inflammation and Alveolar Bone Loss in Rats with Ligature-Induced Periodontitis
-
Bak EJ, Kim JH, Lee DE, Park BH, Ryu JH, Cha JH, Jeon R, Yoo YJ
- KMID: 2170775
- Int J Oral Biol.
- 2012 Jun;37(2):63-68.
It has been documented that SPA0355 exerts anti-inflammatory effects via the inhibition of nuclear factor-kappaB activation. In present study, we investigated the inhibitory effects of SPA0355 on periodontitis in an... -
- CITED
-
- Close
- SHARE
-
- Close
- SPA0355 prevents ovariectomy-induced bone loss in mice
-
Kim SH, Zhang Z, Moon YJ, Park IW, Cho YG, Jeon R, Park BH
- KMID: 2443615
- Korean J Physiol Pharmacol.
- 2019 Jan;23(1):47-54.
- doi: 10.4196/kjpp.2019.23.1.47
Estrogen withdrawal in post-menopausal women leads to overactivation of osteoclasts, which contributes to the development of osteoporosis. Inflammatory cytokines are known as one of mechanisms of osteoclast activation after estrogen... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of DMTU on Adriamycin Induced Changes in Ultrastructure of Hepatocytes in Growing and Adult Rats
-
Paik DJ, Kang YW, Ahn DC, Chang KH, Chung HS
- KMID: 2283070
- Korean J Phys Anthropol.
- 1998 Jun;11(1):95-109.
Adriamycin has been widely used as an anticancer drug in the treatment of thyroid tumor, metastatic breast cancer, sarcoma and lymphoma. The antineoplastic effects of adriamycin result from its inhibitory... -
- CITED
-
- Close
- SHARE
-
- Close
- SPA0355 attenuates ischemia/reperfusion-induced liver injury in mice
-
Bae UJ, Yang JD, Ka SO, Koo JH, Woo SJ, Lee YR, Yu HC, Cho BH, Zhao HY, Ryu JH, Lee SM, Jeon R, Park BH
- KMID: 2155374
- Exp Mol Med.
- 2014 Aug;46(8):e109.
- doi: 10.1038/emm.2014.48
Hepatic ischemia/reperfusion (I/R) injury leads to oxidative stress and acute inflammatory responses that cause liver damage and have a considerable impact on the postoperative outcome. Much research has been performed... -
- CITED
-
- Close
- SHARE
-
- Close
- Protective Roles of Adenosine A1 Receptor Agonist and KATP Channel Opener in Adriamycin induced Cardiac Toxicity
-
Lee S, Cho WG, Paik DJ, Lee BH, Baik TK, Kim WK, Chung HS
- KMID: 2115279
- Korean J Phys Anthropol.
- 2001 Mar;14(1):45-59.
Although adriamycin is a potent chemotherapeutic agent, it elicits serious adverse effects, including cardiac toxicity. Evidence suggests that congestive heart failure induced by adriamycin is mediated by oxidative stress. We... -
- CITED
-
- Close
- SHARE
-
- Close
- The efficacy of SPA0355 in protecting beta cells in isolated pancreatic islets and in a murine experimental model of type 1 diabetes
-
Bae UJ, Song MY, Jang HY, Gim HJ, Ryu JH, Lee SM, Jeon R, Park BH
- KMID: 2154270
- Exp Mol Med.
- 2013 Nov;45(11):e51.
Cytokines activate several inflammatory signals that mediate beta-cell destruction. We recently determined that SPA0355 is a strong anti-inflammatory compound, thus reporting its efficacy in protecting beta cells from various insults.... -
- CITED
-
- Close
- SHARE
-
- Close
- Simultaneous analysis of urinary 2-thiothiazolidine-4-carboxylic acid and thiocarbamide as a biological exposure index for carbon disulfide exposure
-
Roh J, Kim CN, Lim NG, Chang JH, Cho YB
- KMID: 711647
- Yonsei Med J.
- 1999 Jun;40(3):265-272.
- doi: 10.3349/ymj.1999.40.3.265
The objectives of this study were to develop optimal analytic methods for detecting urinary 2-thiothiazolidine-4-carboxylic acid (TTCA) and thiocarbamide simultaneously and to evaluate the usefulness of these metabolites... -
- CITED
-
- Close
- SHARE
-
- Close
- Chemotherapy of Leprosy with Newly Synthesized Thiocarbanilides
-
Chai JL, Chang H, Choi TK
- KMID: 1094458
- Yonsei Med J.
- 1966 Dec;7(1):52-57.
- doi: 10.3349/ymj.1966.7.1.52
Attention has been paid to the thiocarbanilide derivative and the authors synthesized some new compounds of thiocarbanilides for experimental studies on tuberculosis and leprosy. The series of newly synthesized chemical... -
- CITED
-
- Close
- SHARE
-
- Close
