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Allele-related Variation in Minisatellite Repeats Involved in Transcription of the ABO Gene in Korean Blood Donors

Kim SH, Cho D, Kee SJ, Shin MG, Shin JH, Suh SP, Ryang DW

BACKGROUND: The CBF/NF-Y enhancer region of ABO gene reported to contain 43bp minisatellite tandem repeats has been rarely reported. We describe here the relationship between minisatellite tandem repeats and ABO...
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The Association between Multiple Myeloma and Ankylosing Spondylitis: A Report of Two Cases

Moon HI, Chang HJ, Kim JE, Ko HY, Ann SH, Min CK

Multiple myeloma is a malignant disease of plasma cells, whereas ankylosing spondylitis is a chronic inflammatory disease of axial joints. The relationship between the two diseases is uncertain, but chronic...
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A Case of Primary Autoimmune Myelofibrosis

Park SH, Seo YH, Park PH, Ahn JY, Song YH, Kim JE, Park J, Kim KH

Myelofibrosis is usually observed in association with hematologic malignancies or metastatic solid tumors, but it has rarely been reported in patients who suffer with autoimmune disorders. Autoimmune myelofibrosis is a...
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A Case of Acute Myeloblastic Leukemia in a Patient with Behcet's Disease

Cha DH, Kim SK, Kim HJ, Lee N, Nam HS, Choi BG, Lee HW, Kim SG, Choi YJ, Chung JS, Cho GJ

Behcet's disease is a relapsing inflammatory disorder characterized by vasculitis of unknown cause and has been reported rarely in association with malignant diseases. In most cases the autoimmune nature of...
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A Case of Hantavirus Pulmonary Syndrome Mimicking Apalastic Anemia with Invasive Aspergillosis

Yoo KD, Park SH, Kim DM, Seo JY, Lee HR, Yuh YJ, Kim SR, Shin E, Yoo SJ

Hantavirus is known to a causative agent of hemorrhagic fever with renal syndrome and it can cause hantavirus pulmonary syndrome, a rare disease in Korea. Hantavirus pulmonary syndrome is usually...
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A Case of beta Thalassemia Intermedia Due to Hemoglobin Cagliari (beta 60 Val - >Glu)

Park ES, Han HY, Lim JY, Park SS, Kim SY

Beta Thalassemia is a very rare disease in Korea. Only14 mutations have been reported in South Korea to date. This is the first case of beta thalassemia intermedia due to...
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A Case of Chronic Lymphocytic Leukemia Coexisting with Basal Cell Carcinoma and Lung Cancer

Kim DK, Park JC, Choi WH, Kim JH, Han CW

Chronic lymphocytic leukemia (CLL) can be characterized by the accumulation of small mature lymphocytes in the peripheral blood, bone marrow and other lymphoid tissues. It is well known that the...
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A Case of Multicentric Castleman's Disease Diagnosed with Lymph Node Biopsy and Bone Marrow Examination

Park SH, Park CJ, Huh J, Jang S, Chi HS, Suh C

Castleman's disease (CD) is an uncommon lymphoproliferative disorder presenting with a variable spectrum of clinical manifestations. CD is classified into two subtypes, Localized CD and Multicentric CD, by clinical manifestation,...
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A Case of Multiple Myeloma Associated with Multifocal Osteosclerosis (Multiple Myeloma with Osteosclerosis)

Jin SA, Baek SW, Song IC, Yun GW, Yang YJ, Lee HJ, Yun HJ, Kim JM, Jo DY, Kim S

Osteosclerotic myeloma is a rare entity, characterized by single or multiple osteosclerotic bone lesions and usually accompanied by a polyneuropathy syndrome (POEMS). Multiple myeloma with osteosclerotic lesions without polyneuropathy is...
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T-cell Large Granular Lymphocytic Leukemia: A Case Report

Song SH, Chung SM, Hwang DW, Choi JY, Yoo KD, Hong HS, Ahn YW, Roh YW, Lee JS, Park BB, Choi JH, Kim IS, Lee WS, Lee YY

T cell large granular lymphocytic leukemia (T-LGL leukemia) is defined as a clonal proliferative disorder of CD3+ cytotoxic T cells. T-LGL leukemia usually expresses CD3+, CD4-, CD8+, CD16+, CD56- and...
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A Case Report of Rituximab Therapy for Recurrent Thrombotic Thrombocytopenia Purpura

Lee S, Lee JH, Choi Y, Yu JH, Chun YH, Choi WJ, Jung SS

Thrombotic thrombocytopenic purpura (TTP) is a rare medical condition characterized by thrombocytopenia, microangiopathic hemolytic anemia, neurologic manifestations, and infrequently, renal involvement. In many cases, TTP is associated with deficiency of...
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Post-operative Bleeding due to Acquired Hemophilia Successfully Treated with Recombinant Factor VIIa: Case Report

Lee N, Yoon SH, Lim W, Kim MH, Kim HJ, Kim SK, Park JS, Seol YM, Song MK, Choi YJ, Chung JS, Cho GJ

Acquired hemophilia is a rare but potentially life-threatening hemorrhagic disorder caused by the development of autoantibodies against coagulation factor VIII. Concentrates of human factor VIII, desmopressin, activated prothrombin complex concentrates,...
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A Case of Acute Myeloid Leukemia with Mediastinal Sarcoma

Nam YH, Lee JH, Kwon KA, Lee S, Oh SY, Kim SH, Kwon HC, Han JY, Hong SH, Kim HJ

Myeloid sarcoma (MS) is a solid extramedullary tumor that is composed of immature myeloid cells. The incidence of MS in patients with acute myeloid leukemia (AML) has been reported to...
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Reversible Posterior Leukoencephalopathy Syndrome in a Patient with Relapsed Hodgkin's Disease: A Case Report

Kim JW, Moon JM, Kang EJ, Choi YJ, Kim JS, Choi JG, Seo HY, Sung HJ, Choi CW, Kim BS, Kim JS, Seo WK

Reversible posterior leukoencephalopathy syndrome (RPLS) is a distinctive clinicoradiological entity that's characterized by headache, confusion, seizure and frequent visual disturbances. It is associated with certain neuro-radiological findings, and predominantly white...
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