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Polymerase Chain Reaction and Sequencing of Immunoglobulin Heavy Chain Gene Rearrangement in Formalin Fixed, Paraffin-embedded Tissue of Patients with B Cell Lymphoma

Cho SR, Park IJ, Lee MS, Kim EK, Lee WG, Han JH, Park JE, Park JS, Kim HC

BACKGROUND: Immunoglobulin heavy chain (IgH) gene rearrangement has been known to be a useful marker for determining the clonality as well as detecting minimal residual disease in B cell malignancies....
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A Case of Massive Intravascular Hemolysis Associated with Clostiridium perfringens Sepsis

Park KS, Kang SY, Lee WI

Clostridium perfringens is an anaerobic, gram-positive rod that inhabits the soil and the intestinal tracts of many animals, including humans. C. perfringens is a major cause of food poisoning, traumatic...
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A Case of Acute Promyelocytic Leukemia with PML/RARA Translocation Showing Familial t(9;15)(q34;q22)

Shin SY, Koo SH, Kwon KC, Park JW, Ko CS, Jo DY

We report the unusual case of an APL patient with a familial t(9;15)(q34;q22) and acquired t(15;17) (q22;q21). This is unique in that the patient had a constitutional abnormality with the...
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Small Intestinal Mucosa Associated Lymphoid Tissue (MALT) Lymphoma in a Child Presenting with Recurrent Intussusception: A Case Report

Seo HE, Lee JH, Park TI, Lee KS

Mucosa associated lymphoid tissue (MALT) lymphoma is a malignant B cell lymphoma that develops from MALT. The stomach is the most common site of MALT lymphomas but be found anywhere...
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Influential Factors for Engraftment in Autologous Peripheral Hematopoietic Stem Cell Transplantation (APBSCT)

Jeung KJ, Kang MS, Kwon KD, Kim KH, Lee JC, Lee SC, Kim HJ, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Won JH, Hong DS, Park HS

BACKGROUND: Autologous peripheral hematopoietic stem cell transplantation (APBSCT) has been widely used to treat various types of hematological disorders, metabolic diseases and congenital immunodeficiency. Hematopoietic recovery is important because prolonged...
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A Case of Ganglioneuroblastoma Presenting as Weakness of the Lower Extremities

Yun DH, Park KT, Park BK, Im YJ, Hong EK, Lee KS, Kim HJ, Kim HJ

Ganglioneuroblastoma is a rare tumor originating from the sympathetic chain. It is intermediate between the highly malignant neuroblastoma and the benign ganglioneuroma. The predilection sites of ganglioneuroblastoma are the retroperitoneum...
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Hypercalcemia and Extensive Osteolytic Lesion with Increased Plasma Prostaglandin E2 Level in a Child with Acute Lymphoblastic Leukemia

Lee YH, Lim YJ, Bae JJ, Kim JY, Shin JH

In this report, we present a rare case of childhood ALL with hypercalcemia and extensive osteolytic lesions. The case was a 7-year-old girl presenting with vomiting and aggravating bone pain....
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Rituximab-induced Interstitial Pneumonitis in a Young Patient: A Case Report and Review of the Literature

Lee DM, Oh SY, Yoon HA, Lee S, Kim SH, Kwon HC, Lee SK, Kim HJ

Side effects of rituximab are mild in most cases, but there have been a few cases of severe pulmonary toxicity reported in elderly patients. Here we report a case of...
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Two Cases of Acute Leukemic Transformation with a Chromosome 17 Abnormality and p53 Overexpression Evolving from Essential Thrombocythemia

Cho YU, Chi HS, Jang S, Park CJ, Seo EJ, Lee JH

Essential thrombocythemia (ET) is a clonalmyeloproliferative disorder that can rarely transform into acute leukemia in 1~5% of cases. A recent study has found that a significant proportion of leukemic cases...
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A Case of Small Cell Carcinoma of Unknown Primary

Cho SY, Kang SY, Lee JJ, Lim SJ, Lee WI

Small cell carcinoma with unknown primary (SCUP) is an uncommon cancer. Histologically, SCUP has been included with extrapulmonary small cell carcinoma (EPSCC) that is defined as a biopsy proven small...
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Rituximab and ESHAP as Second-line Therapy for Relapsed or Primary Refractory Diffuse Large B Cell Lymphoma: The Experience of a Single Center in Korea

Ko OB, Kim S, Lee DH, Kim SW, Huh J, Suh C

BACKGROUND: The remission status prior to autologous stem cell transplantation (ASCT) influences the transplantation outcome in patients with relapsed or primary refractory diffuse large B cell lymphoma (DLBCL), a complete...
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Effect of Extracorporeal Photopheresis on Steroid Resistant Acute GVHD Refractory to High Dose Steroid Treatment

Kim SY, Lee JW, Min CK, Cho BS, Eom KS, Kim YJ, Lee S, Kim HJ, Cho SG, Kim DW, Min WS, Kim CC

BACKGROUND: The mortality of patients with steroid resistant acute graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT) is high due to multiple organ failure and infection. Recently, the...
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A Case of Primary Tracheal Lymphoma of a 65-year-old Female: Extremely Rare Primary Localization of a Diffuse Large B-cell Lymphoma

Ko YS, Lim YJ, Yang JH, So CS, Kim MJ, Park SH, Park S, Huh MN, Kim JH, Kim CH, Shim JW, Hwang HS, Park YI, Jung JY

Primary extranodal non-Hodgkin's lymphomas comprise approximately 10% of all non-Hodgkin's lymphomas. However, primary tracheal non-Hodgkin's lymphoma is extremely rare, being mainly mucosa-associated lymphoid tissue lymphoma. A 65-year-old female has dry...
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Treatment Outcomes and Toxicities of ABVD Combination Chemotherapy Compared with CVPP in Hodgkin's Disease

Choi YS, Kim BS, Seo HY, Sung HJ, Park KH, Choi IK, Kim SJ, Oh SC, Seo JH, Choi CW, Shin SW, Kim YH, Kim JS

BACKGROUND: We retrospectively evaluated the treatment outcomes and toxicities of Hodgkin's disease (HD) patients treated by ABVD (adriamycin, bleomycin, vinblastine, and dacarbazine) combination chemotherapy, and compared them with those of...
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Development of a New Blood Typing Kit Using the Microfluidics Separation Technique

Suh IB, Ryu SW, Lee Y, Hur DS, Chung C, Chang JK, Lim CS

BACKGROUND: Blood typing is an essential test for transfusion. Generally, blood typing is performed using a slide test, tube test or microcolumn agglutination test. The aims of this study were...
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Outcome of Hematopoietic Stem Cell Transplantation: In Children and Adolescent Patients at Yeungnam University Hospital

Lee YJ, Lee HD, Hah JO, Kim MK, Lee KH, Hyun MS

BACKGROUND: The results of hematopoietic stem cell transplantation (HSCT) have been variable according to the patient disease status and center of treatment. We evaluated the outcome of HSCT in our...
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Risk Factors of Bloodstream Infection Associated Mortality in Pediatric Patients with Hemato-oncologic Disease

Park HW, Youn HS, Im HJ, Kim MN, Seo JJ, Moon HN

BACKGROUND: Bloodstream infection is one of the important causes of mortality, and morbidity in pediatric patients with hemato-oncologic disease. The purpose of this study was to identify the risk factors...
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Free Erythrocyte Protoporphyrin for Diagnosis of Iron Deficiency and Iron Deficiency Anemia in Adolescent Female Athletes

Kim DH, Kim SJ, Kim SK, Son BK, Cho HI

BACKGROUND: If hemoglobin (Hb) synthesis is impaired by factors other than a deficiency in free erythrocyte protoporphyrin (FEP) synthesis, the amount of FEP might be increased. In this study, we...
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Final Height of Children after Stem Cell Transplantation

Park EY, Baek HJ, Han DK, Lee SJ, Cho YK, Kim YO, Kim CJ, Kook H, Woo YJ, Hwang TJ

BACKGROUND: Growth impairment is a common complication after hematopoietic stem cell transplantation (SCT). The aim of this study was to evaluate the final adult height of patients who underwent SCT...
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The Results of Danazol Therapy in Patients with Chronic Immune Thrombocytopenic Purpura Who Failed with Corticosteroid Therapy

Lee JB, Mun YC, Park HS, Choi MY, Chang HJ, Lee KE, Nam EM, Lee SN, Sung CM

BACKGROUND: Most of adult patients with chronic immune thrombocytopenic purpura (ITP) that was refractory or relapsed to high-dose corticosteroid have been treated with splenectomy as a 2nd line treatment. However,...
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