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A Case of Insulinoma Associated with Type 2 Diabetes Mellitus

Yoo SS, Shim WS, Kim CH, Ha KC, Lye SM, Kim EJ, Kim SH, Hong SB, Nam M, Kim YS

An insulinoma is an endocrine tumor of the pancreas derived from the beta cells with abnormal insulin secretion. An insulinoma is rare, the incidence being estimated at only four per...
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Association of Kir6.2 and Peroxisome Proliferator-activated Receptor-gamma (PPARgamma) Polymorphisms with Type 2 Diabetes in Koreans

Lee JE, Kim SW, Seo HA, Jeon JH, Moon SS, Kim HK, Doh YJ, Kim BW, Kim JG, Yoo M, Lee IK

BACKGROUND: The type 2 diabetes is a typical polygenic disease complex, for which several common risk alleles have been identified. Several variants may contribute significantly to the risk of type...
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The Role of Glomerular Podocytes in Diabetic Nephropathy

Lee EY, Chung CH

Diabetic nephropathy is the most common cause of end-stage renal disease and accounts for significant morbidity and mortality among individuals with diabetes mellitus. Therefore, the clarification of the pathogenesis of...
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Inflammatory Markers are Associated with Microvascular Complications in Type 2 Diabetes

Yang SM, Kim SY, Lee KY, Kim YS, Nam MS, Park IB

BACKGROUND: Inflammatory markers are known to be sensitive predictors of atherosclerotic disease such as coronary heart disease. Diabetic patients have higher level of inflammatory markers such as fibrinogen, high sensitivity...
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The Plasma Adiponectin Levels in Patients with Newly Diagnosed Type 2 Diabetes

Lee IS, Kim YJ, Kim JI, Park JH, Ku BJ, Park KS, Lee TY, Kim YK

BACKGROUND: Adiponectin is secreted from adipose tissue and plays an important role in the regulation of glycemia and insulin resistance. In this study, the relationship between adiponectin and the adiposity,...
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A Case of Cured Diabetes Mellitus after Occult Malignant Pheochromocytoma Removal

Cho HC, Kim HS, Kim YJ, Hah YJ, Kim NK, Kim MK, Park KG, Kim YH, Kwon SY

Pheochromocytoma is characterized by a combination of various clinical manifestations that include the classic triad of severe headache, palpitations and diaphoresis. In addition, hyperglycemia can be caused by overproduction of...
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The Effect of Alpha-Lipoic Acid on the Protection of Epidermal Nerve Fibers and Microcapillaries in the Streptozotocin-Induced Diabetic Rats

Piao MH, Jin HY, Song SK, Kang SM, Kim SY, Park JH, Baek HS, Park TS

BACKGROUND: Diabetic neuropathy is associated with risk factors for macrovascular diseases and other microvascular complications. Alpha-lipoic acid (ALA) administration has been reported to improve metabolic abnormalities and ameliorate peripheral polyneuropathy...
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Relationship between Endothelial-dependent/-independent Vasodilation and Carotid Intimal- media Thickness in Newly-diagnosed Korean Type 2 Diabetic Patients

Choi JH, Min KW, Kim HJ, Koo BK, Lim CY, Kim HJ, Pak GS, Han KA, Kim EJ

BACKGROUND: The relative effect of diabetes on the risk of cardiovascular disease in Asian population is much the same as that in Western populations. Although multiple atherosclerotic risk factors have...
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Comparison of Minicircle with Conventional Plasmid for the Non-viral Vascular Endothelial Growth Factor (VEGF) Gene Therapy

Kwon M, Lee S, Chung H, Yoon C, Kim M, Park J

BACKGROUND: Delayed wound healings in diabetic patients are related with the impairment of the expressions of various growth factors. Treatments using growth factors have been attempted on diabetic foot ulcer....
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Peroxisome Proliferator-activated Receptor-gamma (PPARgamma) Polymorphism in Korean Women with Polycystic Ovary Syndrome

Oh JY, Lee H, Hong YS, Sung YA, Chung HW

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disease affecting 5~10% of women with reproductive age. Familial aggregation suggests the evidence supporting a genetic basis for PCOS. The mode...
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