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Effects of Benzo[a]pyrene, 2-Bromopropane, Phenol and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Proinflammatory Cytokines Gene Expression by Mice Spleen Cells

Kim HJ, Kang BN, Cho SW, Son HY, Jeong KS, Park SJ, Kim SH, Kim SR, Kim TH, An MY, Ryu SY

  • KMID: 1097340
  • J Vet Sci.
  • 2002 Dec;3(4):247-254.
The detrimental effects of environmental pollutants on the health of the individual are generally accepted, although the mechanisms of these effects remain to be incompletely understood. In the present study,...
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Signaling pathway for 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages

Cheon HJ, Woo YS, Lee JY, Kim HS, Kim HJ, Cho S, Won NH, Sohn J

  • KMID: 756076
  • Exp Mol Med.
  • 2007 Aug;39(4):524-534.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototypic halogenated aromatic hydrocarbon (HAH), is known as one of the most potent toxicants. At least a part of its toxic effects appears to be derived from...
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In Utero Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Affects the Development of Reproductive System in Mouse

Jin MH, Ko HK, Hong CH, Han SW

PURPOSE: Exposure of male reproductive organs to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) has been reported to cause developmental changes. In this study, we evaluated the effects of in utero TCDD exposure on male...
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Neurotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells

Kim SY, Yang JH

  • KMID: 1033102
  • Exp Mol Med.
  • 2005 Feb;37(1):58-64.
An environmental pollutant, tetrachloro dibenzo dioxin (TCDD) is known to illicit the cognitive disability and motor dysfunction in the developing brain. TCDD induced effects leading to neurodevelopmental and neurobehavioral deficit...
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