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Zebrafish Larvae Model of Dilated Cardiomyopathy Induced by Terfenadine

Gu G, Na Y, Chung H, Seok SH, Lee HY

BACKGROUND AND OBJECTIVES: Dilated cardiomyopathy can be the end-stage of severe cardiac disorders and directly affects the cardiac muscle, inducing cardiomegaly and heart failure (HF). Although a wide variety of...
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Therapeutic Effect of Combination Treatment of Antihistamine and Montelukast in Allergic Rhinitis

Son HR, Lee KI, Chung YJ, Mo JH

  • KMID: 2297561
  • J Rhinol.
  • 2013 May;20(1):20-25.
BACKGROUND: Montelukast is a type 1 cysteinyl-leukotrienes receptor antagonist that has been widely used in allergic disease. However, the effect of combination of leukotriene receptor antagonist and antihistamine is controversial....
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Aquagenic Urticaria: A Report of Two Cases

Park H, Kim HS, Yoo DS, Kim JW, Kim CW, Kim SS, Hwang JI, Lee JY, Choi YJ

Aquagenic urticaria is a rare form of physical urticaria, in which contact with water evokes wheals. A 19-year-old man and a 4-year-old boy complained of recurrent episodes of urticaria. Urticaria...
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Fexofenadine-Induced Urticaria

Lee SW, Byun JY, Choi YW, Myung KB, Choi HY

Fexofenadine (Allegra(R) 180) is a second-generation antihistamine. It is widely used as anti-allergic drug, which suppresses various allergic reactions mediated by histamines. A few cases of H1-antihistamine-induced urticaria have been...
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A Case of Chronic Urticaria Presenting with Double Primary Malignancies in the Stomach and the Colon

  • KMID: 2299567
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Sep;29(3):208-211.
Chronic urticaria is a common disabling skin condition. Neoplasm has been case-reported as a comorbid disease with urticaria, although there is no reliable evidence suggesting a strong association between these...
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Two Cases of Urticaria Induced by Ebastine

  • KMID: 2299580
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Mar;29(1):64-68.
Ebastine (ebastel(R)) is one of the most frequently used antihistamines for allergic diseases. It is a long-acting H1 receptor antagonist belonging to the family of piperidines. Recently, we experienced 2...
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Co-prescribing Patterns of Contraindicated Drugs for the Elderly Patients in Busan

Choi NK, Jung SY, Park BJ

  • KMID: 2233459
  • Korean J Epidemiol.
  • 2008 Jun;30(1):128-136.
PURPOSE: To estimate the prevalence of co-prescribing contraindicated drugs for elderly patients in Busan. METHODS: We used the Health Insurance Review Agency (HIRA) claims database. Study population consisted of elderly patients...
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Efficacy and Safety of Fexofenadine in the Treatment of Pruritus Associated with Eczema

Kim YH, Ko JY, Moon KC, Park YM, Seo YJ, Yoo JH, Lee KH, Lee SC, Lee AY, Kim SE, Jang HS, Haw CL, Ro YS

  • KMID: 2302100
  • Korean J Dermatol.
  • 2008 Feb;46(2):151-159.
BACKGROUND: Fexofenadine (Allegra(R)) is a H1-receptor selective antihistamine which exhibits consistent efficacy and safety in the treatment of allergic diseases. We thought that fexofenadine may be useful in treatment of...
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Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells

Lampiasi N, Azzolina A, Montalto G, Cervello M

  • KMID: 1047079
  • Exp Mol Med.
  • 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on...
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A comparative study of intranasal budesonide and oral terfenadine in perennial allergic rhinitics: effect on the symptom score and nasal secretion eosinophils

Lee BJ, Kim YJ, Kim JH, Shin HS, Chung YS

  • KMID: 2285958
  • J Asthma Allergy Clin Immunol.
  • 2001 Apr;21(2):216-222.
BACKGROUND: Eosinophilia in the nasal secretion and mucosal tissues is the characteristic finding of allergic rhinitis. We compared the effects of nasal budesonide dipropionate and oral terfenadine on the symptom...
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A Case of Hydroxyzine Induced Torsades de Pointes

Kwon JW, Kang WC, Lee MH, Ahn SK, Kim SS

Torsades de pointes is a polymorphic ventricular tachycardia associated with prolonged QT interval and increased U wave amplitude. It has been found to be induced by various drugs, electrolyte imbalances,...
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A Case of Torsade de Pointes after Combined Use of Terfenadine and Itraconazole

Ahn HS, Lim ST, Lee SO, Chai JK, Kim WH, Ko JK

Torsade de pointes is a life-threatening, polymorphic ventricular tachycardia associated with prolongation of the QTc interval. Although torsade de pointes is found in many clinical settings, it is mostly drug...
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A Case of Torsade de Pointes after Treatment with Terfenadine and Ketoconazole

Oh SK, Kuk H, Lim SB, Jeong JW, Park YK, Park OK

Torsade de pointes (TdP) is a form of polymorphic ventricular tachycardia that is associated with prolongation of the QT interval. Although it occurs in many clinical settings, torsade de pointes...
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Torsades de Pointes After Combined Treatment of Terfenadine and Ketoconazole

Park SJ, Kim KH, Kim JS, Ryu JC, Joo SB, Gwon HC, Park SW, Kim DK, Lee SH, Hong KP, Park JE, Lee WR

  • KMID: 2115686
  • Korean J Med.
  • 1998 Jan;54(1):124-130.
Terfenadine is widely used because of nonsedating effect. But It could rarely provoke a potentially lethal ventricular tachyarrhythmia. Recently, we experienced two cases of torsades de pointes(TDP) of occurred after...
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Torsade de Points Ventricular Tachycardia Associated with Piprinhydrinate(Diphenylpyraline, Plokon(R))

Doo YC, Hahn TH, Kim DK, Cho BD, Koh SH, Han KR, Oh DJ, Ryu KH, Rim CY, Koh YB, Lee Y

Torsade de Points is unique polymorphic ventricular tachycardia associated with QT interval prolongation. The mechanism of Torsade de Points was not defined exactly but triggered activity associated with afterdepolarization and/or...
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Comparison of cetirizine and terfenadine in the treatmebt of perennial rhinitis

Kim YY, Cho SH, Min KU

  • KMID: 2046513
  • Allergy.
  • 1994 Sep;14(3):289-296.
A double blind placebo controlled cross over study was carried out in 60 patients with perennial rhinitis to assess the efficacy and safety of once daily 10mg eetiriz-ine and twice...
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