Ann Dermatol.  2011 Dec;23(Suppl 3):S371-S374. 10.5021/ad.2011.23.S3.S371.

Aquagenic Urticaria: A Report of Two Cases

• Park H
• Kim HS
• Yoo DS
• Kim JW
• Kim CW
• Kim SS
• Hwang JI
• Lee JY
• Choi YJ

• KMID: 2171875
• DOI: http://doi.org/10.5021/ad.2011.23.S3.S371

Abstract

Aquagenic urticaria is a rare form of physical urticaria, in which contact with water evokes wheals. A 19-year-old man and a 4-year-old boy complained of recurrent episodes of urticaria. Urticaria appeared while taking a bath or a shower, in the rain, or in a swimming pool. Well-defined pin head to small pea-sized wheals surrounded by variable sized erythema were provoked by contact with water on the face, neck, and trunk, regardless of its temperature or source. Results from a physical examination and a baseline laboratory evaluation were within normal limits. Treatment of the 19-year-old man with 180 mg fexofenadine daily was successful to prevent the wheals and erythema. Treatment with 5 ml ketotifen syrup bid per day resulted in improvement of symptoms in the 4-year-old boy.

Keyword

Aquagenic urticaria; Water

MeSH Terms

Baths
Erythema
Head
Humans
Ketotifen
Neck
Physical Examination
Preschool Child
Rain
Swimming Pools
Terfenadine
Urticaria
Water
Young Adult
Ketotifen
Terfenadine
Water

Figure

• 

  Fig. 1 Pin-head to match-head sized wheal surrounded by erythema on the upper trunk after the water provocation test.

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  Fig. 2 Pin-head sized wheal surrounded by erythema on the face after the water provocation test.

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