- The effect of prostaglandin E2 on experimental pancreatitis inducedby sodium taurocholate in rat
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Nam HW, Song HW, Jee YK, Lee TK, Yang JS, Lee BH, Han CS, Kim HS, Han KR, Suh JI
- KMID: 1685239
- Korean J Gastroenterol.
- 1991 May;23(2):557-562.
No abstract available. -
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- Biliary Bile Acid Analysis in the Patients with Bile Duct Cancer
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Lee JH, Park YH, Seo JH, Chung JB, Lee SJ, Chung JP, Song SY, Kang JK
- KMID: 2304632
- Korean J Gastroenterol.
- 2000 Jan;35(1):103-110.
BACKGROUND/AIMS: Bile acids including deoxycholic acid (DCA) have been known as carcinogenic on human colonic mucosa. However, limited data on changes of bile acid composition in the patients with bile duct cancer are... -
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- Bile acid modulation of gastroinstinal smooth muscle contraction and ionic currents
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Lee HK, Lee KH
- KMID: 1917027
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):333-338.
We have examined whether bile acids can affect the electrical and mechanical activities of circular smooth muscle of canine colon and ileum, using isometric tension measurement or patch clamp technique. It was found... -
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- Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes
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Kim YH, Shin MJ
- KMID: 1081461
- Exp Mol Med.
- 2002 May;34(2):123-130.
Membrane-associated cytotoxicity induced by hydrophobic bile salts is a major contributing factor leading to liver diseases. Administration of ursodeoxycholate reduces serum liver enzymes in chronic liver diseases but the nature... -
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- Effects of Intravenous Administration of Taurocholate on Hepatic Thiol Methyltransferase Activity in Cholestatic Rat
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Rhee BW, Kwak CS
- KMID: 2209473
- J Korean Surg Soc.
- 2002 Jul;63(1):1-10.
PURPOSE: The possible mechanisms of increased thiol me thyltransferase (TMT) activity in cholestatic rat livers and serum were studied. METHODS: Rats were divided into seven groups: rats receiv ing a... -
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- Induction of Rat Liver gamma-Glutamyl Transpeptidase by Bile Acid Load
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Kim SK, Kim YH
- KMID: 1531715
- Korean J Hepatol.
- 1997 Sep;3(3):210-226.
BACKGROUND/AIMS: In order to elucidate the possible mechanism of increase of y-glutamyl transpeptidase (y-GTP) activity in cholestatic liver and serum was studied. METHOD: Rats were divided into eight groups: Normal, sham operated... -
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- Effects of Intravenous Administration of Taurocholate on Liver and Serum Thiosulfate Sulfurtransferase Activities in Cholestatic Rat
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Rhee BW, Kwak CS
- KMID: 2325031
- J Korean Surg Soc.
- 2004 May;66(5):359-366.
PURPOSE: To Study the possible mechanisms of change of thiosulfate sulfurtransferase (TST) activity in cholestatic rat liver and serum. METHODS: Rats were divided into seven groups: those receiving a sham... -
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- Induction of Hepatic Arylamine N-Methyltransferase by a Taurocholate Load in Rats
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Rhee BW, Kwak CS
- KMID: 2325094
- J Korean Surg Soc.
- 2000 Aug;59(2):141-153.
PURPOSE: The possible mechanisms of increased arylamine N-methyl- transferase (AMT) activity in cholestatic rat livers and serum were studied. METHODS: Rats were divided into eight groups: rats receiving a... -
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- N-Acetylcysteine Improves Pancreatic Microcirculation and Alleviates the Severity of Acute Necrotizing Pancreatitis
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Du BQ, Yang YM, Chen YH, Liu XB, Mai G
- KMID: 1431355
- Gut Liver.
- 2013 May;7(3):357-362.
- doi: 10.5009/gnl.2013.7.3.357
BACKGROUND/AIMS: To investigate the beneficial effect of N-Acetylcysteine (NAC) on pancreatic microvascular perfusion in acute necrotizing pancreatitis (ANP). METHODS: Fifty-four rats were divided into a control group, an ANP group and... -
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- Taurine-conjugated Bile Acids Induce Nuclear Factor-Kappa B Mediated Interleukin-8 Activation in Gastric Epithelial Cell Lines
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Kim HS, Lee DK, Seo JI, Baik SK, Kwon SO, Kim HY, Kim WH
- KMID: 1864975
- Korean J Gastroenterol.
- 2002 Mar;39(3):204-215.
BACKGROUND/AIMS: The molecular mechanism of gastric epithelial injury induced by bile acid remains poorly understood. The aims of this study were to examine whether IL-8 was expressed by the stimulation... -
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- Receptor for Hepatitis B and D Virus
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Kim KH
- KMID: 2269047
- Korean J Med.
- 2015 Jul;89(1):35-42.
- doi: 10.3904/kjm.2015.89.1.35
Chronic hepatitis B affects 400 million people worldwide and is one of the leading causes of liver-related morbidity and mortality. All clinically available hepatitis B virus (HBV) drugs are nucleoside... -
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- The Role of Sodium-taurocholate Co-transporting Polypeptide as a Receptor during HBV Infection
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Kim SY, Jang E, Inn KS
- KMID: 2366883
- J Bacteriol Virol.
- 2016 Dec;46(4):335-342.
- doi: 10.4167/jbv.2016.46.4.335
According to World Health Organization, more than 200 million people suffer with chronic hepatitis caused by Hepatitis B virus (HBV) infection worldwide. Chronic hepatitis B causes various complications including liver... -
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- The Severity of Acute Lung Injury in Experimental Acute Pancreatitis
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Kim KH, Kim CD, Kim YS, Hyun JH
- KMID: 2251398
- Korean J Med.
- 1998 Sep;55(3):295-301.
OBJECTIVES: About 60% of all deaths due to acute pancreatitis occur within the first 7 days of onset and associated with acute lung injuries. Lung injury include pulmonary infiltration, pulmonary... -
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- Anotioxidant Effect of Calcium Channel Blocker on Acute Necrotizing Pancreatitis in Rats
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Kim IH, Roe IH, Park SH, Yang MR, Lim CY, Lee MI, Oh HT, Cho JH, Kim SB, Huh JH
- KMID: 2084959
- Korean J Gastroenterol.
- 1999 Sep;34(3):372-380.
BACKGROUND/AIMS: Cellular calcium, a key physiological signaling element in cell function and also a crucial pathological intracellular messenger in cell injury, appears to be involved in the initiation and development... -
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- Effects of Local Pancreatic Renin-Angiotensin System on the Microcirculation of Rat with Severe Acute Pancreatitis
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Pan Z, Feng L, Long H, Wang H, Feng J, Chen F
- KMID: 2285572
- Korean J Physiol Pharmacol.
- 2015 Jul;19(4):299-307.
- doi: 10.4196/kjpp.2015.19.4.299
Severe acute pancreatitis (SAP) is normally related to multiorgan dysfunction and local complications. Studies have found that local pancreatic renin-angiotensin system (RAS) was significantly upregulated in drug-induced SAP. The present... -
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- Development of an acute pancreatitis porcine model based on endoscopic retrograde infusion of contrast medium or sodium taurocholate
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Park JS, Jeong S, Kim JM, Lee BH, Kim JM, Lee DH
- KMID: 2463482
- Korean J Intern Med.
- 2019 Nov;34(6):1244-1251.
- doi: 10.3904/kjim.2017.367
BACKGROUND/AIMS: A reproducible, endoscope-based, large animal model, of acute pancreatitis was developed to meet the need for a suitable means of preclinically testing treatments. The aim of this study was... -
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- Involvement of Oxidative Stress in Sodium Taurocholate-Induced Acute Necrotizing Pancreatitis in Rats
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Jeon KC, Lee HG, Park JK, Kim JT, Ryu JW, Park DK, Chung M, Yang MR
- KMID: 2005572
- J Korean Surg Soc.
- 1998 Aug;55(2):151-159.
Oxidative radicals are regarded as a major factor in the pathogenesis of both acute and chronic pancreatitis. Because oxygen radicals react most readily with polyunsaturated fatty acids, resulting in peroxidation... -
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- In vivo Assessment for the Antioxidant Activity of the Calcium Channel Blocker Nicardipine in 3% Sodium-Taurocholate-induced Acute Pancreatitis
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Seo JJ, Lee HG, Park JK, Kim JT, Park DK, Chung M, Roe IH, Yang MR
- KMID: 2206401
- J Korean Surg Soc.
- 1998 Oct;55(4):469-477.
BACKGROUND: Although several pathophysiological sequences, such as protease activation, free radical generation, and inflammatory mediator release, have been described in acute pancreatitis, the precise mechanism by which acute pancreatitis is... -
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- Interactions of Unconjugated Bilirubin with Bile Acid by Rapid Solvent Partition
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Hahm JS, Mun GH, Lee HL, Eun CS, Park JY, Han DS, Choi HS, Ahn YH
- KMID: 863071
- Korean J Hepatol.
- 2002 Mar;8(1):80-89.
BACKGROUND/AIMS: Our previous studies of ionization and solubility of unconjugated bilirubin (UCB) yielded inappropriately large differences between the two carboxylic pK'a values of UCB. These data, however, were not... -
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