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Novel foot-and-mouth disease virus in Korea, July-August 2014

Park JH, Tark D, Lee KN, Lee SY, Ko MK, Lee HS, Kim SM, Ko YJ, Seo MG, Chun JE, Lee MH, Kim B

Despite nation-wide immunization with O, A, and Asia 1 type vaccines in Republic of Korea, foot-and-mouth disease type O occurred again in July 2014 after three years and three months....
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Control of type O foot-and-mouth disease by vaccination in Korea, 2014–2015

Park JH, Tark D, Lee KN, Chun JE, Lee HS, Ko YJ, Kye SJ, Kim YJ, Oem JK, Ryoo S, Lim SB, Lee SY, Choi JH, Ko MK, You SH, Lee MH, Kim B

On December 3, 2014, a type O foot-and-mouth disease (FMD) outbreak began in Korea. Although vaccinations were administered, FMD cases increased steadily for five months, and reached 185 cases by...
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Antigenic properties and virulence of foot-and-mouth disease virus rescued from full-length cDNA clone of serotype O, typical vaccine strain

Kim RH, Chu JQ, Park JN, Lee SY, Lee YJ, Ko MK, Hwang JH, Lee KN, Kim SM, Tark D, Ko YJ, Lee HS, Seo MG, Park ME, Kim B, Park JH

We cloned the full-length cDNA of O Manisa, the virus for vaccinating against foot-and-mouth disease. The antigenic properties of the virus recovered from the cDNA were similar to those of...
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A genetically modified rabies vaccine (ERAGS) induces protective immunity in dogs and cattle

Yang DK, Kim HH, Lee SH, Jeong WH, Tark D, Cho IS

PURPOSE: The current live attenuated rabies vaccine must be replaced with a safer vaccine based on the ERAGS strain to prevent rabies in South Korea. We evaluated the safety and...
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Protective efficacy of attenuated Salmonella Typhimurium strain expressing BLS, Omp19, PrpA, or SOD of Brucella abortus in goats

Leya M, Kim WK, Ochirkhuyag E, Yu EC, Kim YJ, Yeo Y, Yang MS, Han SS, Lee JH, Tark D, Hur J, Kim B

Background: Attenuated Salmonella strain can be used as a vector to transport immunogens to the host antigen-binding sites. Objectives: The study aimed to determine the protective efficacy of attenuated Salmonella strain expressing...
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Vaccination of goats with a combination Salmonella vector expressing four Brucella antigens (BLS, PrpA, Omp19, and SOD) confers protection against Brucella abortus infection

Leya M, Kim WK, Cho JS, Yu EC, Kim YJ, Yeo Y, Lyoo KS, Yang MS, Han SS, Lee JH, Tark D, Hur J, Kim B

Salmonella is an intracellular pathogen with a cellular infection mechanism similar to that of Brucella, making it a suitable choice for use in an anti-Brucella immune boost system. This study...
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