- Rapamycin Inhibits Transforming Growth Factor beta1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
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Gao Y, Xu X, Ding K, Liang Y, Jiang D, Dai H
- KMID: 1503908
- Yonsei Med J.
- 2013 Mar;54(2):437-444.
- doi: 10.3349/ymj.2013.54.2.437
PURPOSE: The present study was designed to determine whether rapamycin could inhibit transforming growth factor beta1 (TGF-beta1)-induced fibrogenesis in primary lung fibroblasts, and whether the effect of inhibition would occur... -
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- Bilirubin Activates Transcription of HIF-1alpha in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content
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Kim SG, Ahn SY, Lee ES, Kim S, Na KY, Chae DW, Chin HJ
- KMID: 2069806
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S146-S154.
- doi: 10.3346/jkms.2014.29.S2.S146
The expression of hypoxia-inducible factor (HIF) is influenced by reactive oxygen species (ROS). Effect of bilirubin on HIF-1 expression in proximal tubular cells was investigated under physiological oxygen concentration, which... -
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- Prognostic Significance of p53, mTOR, c-Met, IGF-1R, and HSP70 Overexpression after the Resection of Hepatocellular Carcinoma
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Kang GH, Lee BS, Lee ES, Kim SH, Lee HY, Kang DY
- KMID: 1774532
- Gut Liver.
- 2014 Jan;8(1):79-87.
BACKGROUND/AIMS: The current study examines the expression of molecular biomarkers in hepatocellular carcinoma (HCC) and whether these findings correlate with the clinicopathologic features of the disease and patient survival. METHODS: We... -
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- IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation
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Chen F, Zhu HH, Zhou LF, Wu SS, Wang J, Chen Z
- KMID: 1104208
- Exp Mol Med.
- 2010 Jul;42(7):477-483.
- doi: 10.3858/emm.2010.42.7.049
The scaffold protein IQGAP1 shows elevated levels in several cancer types, but its expression in hepatocellular carcinoma is unknown. We found that 58% of human hepatocellular carcinoma tissue samples had... -
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