- Pathologic study of suramin effects on the cell line of penile squamous cell carcinoma
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Park YW, Moon WC, Song KY
- KMID: 2036130
- J Korean Cancer Assoc.
- 1992 Dec;24(6):767-782.
No abstract available. -
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- Experimental study on the effect of surmin on penile squamous carcinoma cell line(CUPE-1)
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Kang IK, Moon WC
- KMID: 2289324
- Korean J Urol.
- 1993 Oct;34(5):748-763.
Experimental study was done to investigate the effect of suramin on the in vitro and in vivo proliferation and metastasis of penile squamous carcinoma cell line(CUPE-1), morphological changes of CUPE-1... -
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- Effect of suramin on differentiation of human stomach cancer cell lines
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Choe G, Kim WH, Park JG, Kim YI
- KMID: 1081036
- J Korean Med Sci.
- 1997 Oct;12(5):433-442.
- doi: 10.3346/jkms.1997.12.5.433
This study was designed to demonstrate that differentiation of stomach cancer cells can be modified by microenvironmental change and to look for a method inducing or promoting tumor cell... -
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- Effects suramin, tumor necrosis factor-alpha(TNF-alpha, interferon-alpha(IFN-alpha on human renal carcinoma cell line growth
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Cho MK, Kim KD, Kim YS
- KMID: 1913157
- Korean J Urol.
- 1993 Jun;34(3):414-419.
Recently much interest has been expressed for the use of biological response modifiers and growth factor antagonists in the treatment or radiation and chemotherapeutic drug-refractory renal cell carcinoma. Herein antiproliferative... -
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- Effects of exogenous ATP on calcium mobilization and cell proliferation in C6 glioma cell
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Lee EJ, Cha SH, Lee WK, Lee KH, Lee SB
- KMID: 2285204
- Korean J Physiol Pharmacol.
- 1998 Aug;2(4):419-425.
To clarify the effect of extracellular ATP in cultured C6 glioma cells, ATP-induced cytosolic free calcium ((Ca2+)i) mobilization and cell proliferation were investigated. ATP-induced (Ca2+)i increased in a dose-dependent manner (10-7 M apprx... -
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- Effects of ATP and LTC4 on hypoxic pulmonary vasoconstriction in isolated rat lungs
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Rho JY, Shin HY, Kim HC, Lee JW, Kim SD
- KMID: 1765452
- Korean J Anesthesiol.
- 2009 Oct;57(4):472-482.
- doi: 10.4097/kjae.2009.57.4.472
BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) is unique to pulmonary circulation but the mechanism remains elusive. Red blood cells (RBCs) are known to augment HPV and to release more ATP as... -
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- Microglia and Autism Spectrum Disorder: Overview of Current Evidence and Novel Immunomodulatory Treatment Options
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Kim JW, Hong JY, Bae SM
- KMID: 2419977
- Clin Psychopharmacol Neurosci.
- 2018 Aug;16(3):246-252.
- doi: 10.9758/cpn.2018.16.3.246
Autism spectrum disorder is a rapidly increasing heterogeneous neurodevelopmental syndrome, remarked by persistent deficit in social communication, and restricted, repetitive patterns of behavior and interest. Lately, maternal immune activation and... -
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- Effects of Adenosine 5'-Tetraphosphate on the Cardiac Activity*
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Lee JW, Park KS, Kong ID
- KMID: 2093590
- Korean Circ J.
- 1996 Jun;26(3):704-712.
- doi: 10.4070/kcj.1996.26.3.704
BACKGROUND: Adenosine 5'-tetraphosphate(ATPP), an endogenous nucleotide, is stored in cells and released into the extracellular space upon stimulation. Some of the biological responses to ATPP were reported, but characteristics of... -
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- The Effects of Nitric Oxide and Vasoactive Intestinal Peptide on the Smooth Muscle Relaxation of a Guinea Pig's Gastric Fundus
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Park HJ, Lee HY, Chung JP, Lee KS, Chon CY, Kang BS, Park IS
- KMID: 2143767
- Korean J Gastroenterol.
- 1997 Mar;29(3):289-300.
BACKGROUND/AIMS: The autonomic nervous system distributed throughout the stomach consists of adrenergic, cholinergic, and non-adrenergic, non-cholinergic (NANC) nerves. Of these, NANC nerve fibers are known to be distributed all throughout... -
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- Vascular Reactivity by Purinoceptor Activation in Rat Inferior Vena Cava
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Lee BS, Chung HS, Park KS, Kong ID, Jeong SW, Lee JW
- KMID: 2093759
- Korean Circ J.
- 2000 Sep;30(9):1156-1164.
- doi: 10.4070/kcj.2000.30.9.1156
BACKGROUND: Extracellular ATP, released from platelets and nerve endings, plays significant roles in the regulation of circulation. The effects of ATP depend on the location of the vessels and the... -
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- Effects of ATP on Pacemaker Activity of Interstitial Cells of Cajal from the Mouse Small Intestine
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Park IK, Kim JH, Park CG, Kim MY, Parajuli S, Hong CS, Choi S, Jun JY
- KMID: 2458587
- Chonnam Med J.
- 2018 Jan;54(1):63-71.
- doi: 10.4068/cmj.2018.54.1.63
Purinergic receptors play an important role in regulating gastrointestinal (GI) motility. Interstitial cells of Cajal (ICCs) are pacemaker cells that regulate GI smooth muscle activity. We studied the functional roles... -
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- Effects of Uridine 5'-Triphosphate on the Vascular Tone of Rat Thoracic Aorta
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Park KS, Kong ID, Lee JW
- KMID: 2228958
- Korean Circ J.
- 1995 Feb;25(1):68-77.
- doi: 10.4070/kcj.1995.25.1.68
BACKGROUND: Uracil nucleotides are stored in platelets and all other cells, and are released into the extracellular space upon stimulation. They show various biological responses but their actions and mechanism... -
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- Reactive Oxygen Species and Nitrogen Species Differentially Regulate Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons
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Lee HI, Park AR, Chun SW
- KMID: 2170792
- Int J Oral Biol.
- 2014 Dec;39(4):229-236.
- doi: 10.11620/IJOB.2014.39.4.229
Reactive oxygen species (ROS) and nitrogen species (RNS) are implicated in cellular signaling processes and as a cause of oxidative stress. Recent studies indicate that ROS and RNS are important... -
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- Evidence for adenosine triphosphate (ATP) as an excitatory neurotransmitter in guinea-pig gastric antrum
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Kang TM, Xu W, Kim SJ, Ahn SC, Kim YC, So I, Park MK, Uhm DY, Kim KW
- KMID: 1554134
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):165-174.
We explore the question of whether adenosine 5'-triphosphate (ATP) acts as an excitatory neurotransmitter in guinea-pig gastric smooth muscle. In an organ bath system, isometric force of the circular smooth muscle of guinea-pig... -
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- Extracellular Nucleotides Can Induce Chemokine (C-C motif) Ligand 2 Expression in Human Vascular Smooth Muscle Cells
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Kim JI, Kim HY, Kim SM, Lee SA, Son YH, Eo SK, Rhim BY, Kim K
- KMID: 2389106
- Korean J Physiol Pharmacol.
- 2011 Feb;15(1):31-36.
To understand the roles of purinergic receptors and cellular molecules below the receptors in the vascular inflammatory response, we determined if extracellular nucleotides up-regulated chemokine expression in vascular smooth muscle... -
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- The Effects of Neurotransmitters on the Ion Channels in the Isolated Deiters'Cells of Guinea Pig Cochlea
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Nam EC, Kim WT, Leem CH, Chung JW
- KMID: 1923102
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Mar;46(3):191-197.
BACKGROUND AND OBJECTIVES: The supporting cells in the organ of Corti help to maintain the structural integrity of the organ, but it has been suggested that they also actively participate... -
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- Three Gaseous Neurotransmitters, Nitric oxide, Carbon Monoxide, and Hydrogen Sulfide, Are Involved in the Neurogenic Relaxation Responses of the Porcine Internal Anal Sphincter
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Folasire O, Mills KA, Sellers DJ, Chess-Williams R
- KMID: 2379713
- J Neurogastroenterol Motil.
- 2016 Jan;22(1):141-148.
- doi: 10.5056/jnm15036
BACKGROUND/AIMS: The internal anal sphincter (IAS) plays an important role in maintaining continence and a number of neurotransmitters are known to regulate IAS tone. The aim of this study was... -
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- ATP-induced Calcium Mobilization and Proliferation in Cervical Cancer Cells
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An WS, Le GH
- KMID: 2261415
- Korean J Obstet Gynecol.
- 1999 Jun;42(6):1332-1338.
PURPOSE: Nucleotides such as ATP can act as extracellular effector molecules by interaction with specific cellular receptors. To know the role of nucleotides in cervical cancer cells, we observed the... -
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- P2X and P2Y Receptors Mediate Contraction Induced by Electrical Field Stimulation in Feline Esophageal Smooth Muscle
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Cho YR, Jang HS, Kim W, Park SY, Sohn UD
- KMID: 2071699
- Korean J Physiol Pharmacol.
- 2010 Oct;14(5):311-316.
- doi: 10.4196/kjpp.2010.14.5.311
It is well-known that electrical field stimulation (EFS)-induced contraction is mediated by a cholinergic mechanism and other neurotransmitters. NO, ATP, calcitonin gene-related peptide (CGRP), and substance P are released by... -
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