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Astaxanthin Prevents Decreases in Superoxide Dismutase 2 Level and Superoxide Dismutase Activity in Helicobacter pylori-infected Gastric Epithelial Cells

Kim SH, Lim JW, Kim H

BACKGROUND: Helicobacter pylori increases production of reactive oxygen species (ROS), which activates inflammatory and carcinogenesis-related signaling pathways in gastric epithelial cells. Therefore, reducing ROS, by upregulating antioxidant enzyme, such as...
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Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia

Jeon GW, Sheldon RA, Ferriero D

BACKGROUND: Sixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does...
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Effect of superoxide dismutase, catalase, and glutathione peroxidase supplementation in the extender on chilled semen of fertile and hypofertile dogs

Del Prete , Ciani F, Tafuri S, Pasolini M, Della Valle G, Palumbo V, Abbondante L, Calamo A, Barbato V, Gualtieri , Talevi R, Cocchia N

This study investigated the correlation between oxidative stress status and key canine sperm parameters and the effect of addition of a superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx)...
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Superoxide Anion Production by the Spermatozoa of Men with Varicocele: Relationship with Varicocele Grade and Semen Parameters

Alkan I, Yüksel M, Canat HL, Atalay HA, Can O, Özveri H, Başar MM

PURPOSE: To investigate the pathophysiological role of superoxide anion and total reactive oxygen species (ROS) production by the spermatozoa of men with varicocele and its relationship with varicocele grade and...
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The Diagnostic Value of Malondialdehyde, Superoxide Dismutase and Catalase Activity in Drug Naïve, First Episode, Non-Smoker Generalized Anxiety Disorder Patients

Fındıklı E, Camkurt MA, İzci F, Karaaslan , Fındıklı HA, Sümer P, Kurutaş E

OBJECTIVE: Generalized anxiety disorder (GAD) is a common anxiety disorder. Although lots of research done to reveal neurobiological basis of GAD, it is still unclear. Diagnosis of GAD depends on...
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Evaluation of Malondialdehyde, Superoxide Dismutase and Catalase Activity in Fetal Cord Blood of Depressed Mothers

Camkurt MA, Fındıklı E, Bakacak M, Tolun FÄ, Karaaslan

OBJECTIVE: The umbilical cord consists of two arteries and one vein and it functions in the transport between the maternal and fetal circulation. Biochemical analysis of fetal cord blood (FCB)...
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Lower serum extracellular superoxide dismutase levels are associated with polyneuropathy in recent-onset diabetes

Strom A, Kaul K, Brüggemann J, Ziegler I, Rokitta I, Püttgen S, Szendroedi J, Müssig K, Roden M, Ziegler D, GDS Group

Increased oxidative stress is implicated in the pathogenesis of experimental diabetic neuropathy, but translational evidence in recent-onset diabetes is scarce. We aimed to determine whether markers of systemic oxidative stress...
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Propylthiouracil, Perchlorate, and Thyroid-Stimulating Hormone Modulate High Concentrations of Iodide Instigated Mitochondrial Superoxide Production in the Thyroids of Metallothionein I/II Knockout Mice

Duan Q, Wang T, Zhang N, Perera V, Liang X, Abeysekera IR, Yao X

BACKGROUND: Increased oxidative stress has been suggested as one of the underlying mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded as scavengers of reactive oxygen species (ROS) in...
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Adipokines, Superoxide Dismutases and Progression of Symptomatic Intracranial Atherosclerotic Stenosis

Ryu WS, Jeong SW

OBJECTIVE: We aimed to investigate the relationship between adipokines and antioxidation enzyme and the risk of progression of symptomatic intracranial atherosclerotic stenosis (ICAS). METHODS: Of 409 patients who participated in the...
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High yields and soluble expression of superoxide dismutases in Escherichia coli due to the HIV-1 Tat peptide via increases in mRNA transcription

Sun Y, Ye Q, Wu M, Wu Y, Zhang C, Yan W

This study aimed to validate the high yield and soluble expression of proteins carrying the transactivator of transcription (Tat) peptide tag, and further explored the potential mechanism by which the...
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Impact of iron deficiency anemia on chronic periodontitis and superoxide dismutase activity: a cross-sectional study

Chakraborty S, Tewari S, Sharma RK, Narula SC, Ghalaut PS, Ghalaut V

PURPOSE: Both chronic periodontitis (CP) and iron deficiency anemia (IDA) induce oxidative stress in the body and cause an imbalance between reactive oxygen species and antioxidants, such as superoxide dismutase...
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Comparison of Gene Expression Patterns between Helicobacter pylor 26695 and its Superoxide Dismutase Isogenic Mutant

Cho MJ, Lee SG, Lee KH, Song JY, Lee WK, Baik SC, Rhee KH, Youn HS, Seo JH, Kang HL

Helicobacter pylori, a causative agent of gastroduodenal diseases, is a Gram-negative microaerophilic bacterium. Although H. pylori locates in the microaerophilic mucous layer, the bacteria would come into contact harmful reactive...
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Effect of Propofol on Kupffer Cell Superoxide Dismutase Activities and Cytoprotections during Hypoxia-Reoxygenation

Noh YC, Song IH, Kim JY, Seong CR, Jee DL, Sung EG

  • KMID: 2224462
  • Korean J Anat.
  • 2007 Sep;40(3):227-233.
The aims of this study were to verify the hypoxia-reoxygenation injury of primary cultured Kupffer cells and the effect of propofol against the hypoxia-reoxygenation injury through quantitating lactate dehydrogenase (LDH)...
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Expression of Antioxidant Enzymes(Catalase, Superoxide Dismutase, and Glutathione Peroxidase) in Human Bladder Cancer

Jeon SH, Park JH, Chang SG

PURPOSE: Intrinsic antioxidant enzymes(AOE) are essential for protection against potential cellular damage by reactive oxygen species(ROS), which affect many biological processes including carcinogenesis. The aim of the present study was...
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Anticipation and Phenotypic Heterogeneity in Korean Familial Amyotrophic Lateral Sclerosis with Superoxide Dismutase 1 Gene Mutation

Kim W, Kim JS, Lee KS, Gwoun YJ, Kim JM, Lee KH

BACKGROUND AND PURPOSE: Different mutations in the Cu/Zn superoxide dismutase 1 (SOD1) gene have been reported in approximately 10% of cases of familial amyotrophic lateral sclerosis (ALS). The aim of...
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Placental Superoxide Dismutase Activity and Genetic Polymorphism in Preeclampsia and Normal Pregnancy

Park MH, Kim YJ, Ann JJ, Kim JI, Chun SH

  • KMID: 2280566
  • Korean J Perinatol.
  • 2006 Jun;17(2):166-172.
OBJECTIVE: Our purpose was to investigate urinary malondialdehyde (MDA), manganese superoxide dismutase (Mn-SOD) activity and polymorphism in placental tissues of women with preeclampsia and to evaluate oxidative stress in the...
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Expression of Superoxide Dismutase Isoforms in Inflamed Gingiva

Na HJ, Kim OS, Park BJ

  • KMID: 2462853
  • J Korean Acad Periodontol.
  • 2006 Mar;36(1):97-112.
No abstract available.
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The Role of Extracellular Superoxide Dismutase (EC-SOD) in Skeletal Muscle Ischemia-reperfusion Injury

Park JW, Kim SK, Park JH, Hong JS, Wang JH, Song JY

  • KMID: 2106157
  • J Korean Orthop Assoc.
  • 2005 Jun;40(3):347-355.
PURPOSE: This study investigated the role of extracellular superoxide dismutase (EC-SOD), which is a major extracellular antioxidant enzyme in skeletal muscle ischemia and reperfusion (I/R) injury. MATERIALS AND METHODS: The...
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Enhanced Expression of Cell Adhesion Molecules in the Aorta of Diabetic Mice is Mediated by gp91phox-derived Superoxide

Yun MR, Kim JJ, Lee SM, Heo HJ, Bae SS, Kim CD

  • KMID: 2285317
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):109-115.
Endothelial activation and subsequent recruitment of inflammatory cells are important steps in atherogenesis. The increased levels of cell adhesion molecules (CAM) have been identified in diabetic vasculatures, but the underlying...
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The maternal change of malondialdehye levels in plasma and superoxide dismutase levels in plasma and erythrocyte as biologic markers of oxidative stress in pregnancy with preeclampsia

Park MC

  • KMID: 2272727
  • Korean J Obstet Gynecol.
  • 2005 Nov;48(11):2550-2557.
OBJECTIVES: To evaluate lipid peroxidation status and antioxidative systems in preeclamptic pregnancies by measuring plasma malondialdehyde (MDA) and plasma and erythrocyte superoxide dismutase (SOD) activities in women with or without...
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