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TIGR gene in primary open-angle glaucoma and steroid-induced glaucoma

Kee C, Ahn BH

To identify TIGR gene mutation in two Korean pedigrees of primary open-angle glaucoma (POAG), and in 25 steroid-induced glaucoma patients, TIGR gene assay was performed. Genomic DNA was extracted from...
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The effect of growth factor on antigen and viability of corneal endothelial cells

Tchah H

The effect of epidermal growth factor (EGF) on corneal endothelial cell of rabbit, was evaluated. DNA synthesis of cultured corneal endothelial cells after adding EGF to culture medium and major...
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Dapsone maculopathy

Seo MS, Yoon KC, Park YG

After the injection of about 10 gm of dapsone, a 38-year-old male showed a whitish-yellow patch in the macular region of both eyes, with decreased visual acuity of the counting...
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Glutathione transferase (class pi) and tissue transglutaminase (Tgase C) expression in pterygia

Kim YJ, Park ES, Song KY, Park SC, Kim JC

Pterygia are considered to be induced by predisposing factors such as the external toxic environment. Glutathione transferases (GSTs) have a role in the detoxication of toxic chemicals. Transglutaminases (TGases) are...
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Iron-induced cytotoxicity in cultured rat retinal neurons

Sohn J, Yoon YH

Oxidative stress has been proposed as a major injury mechanism in the central nervous system including the retina. In this study, as an initial attempt to study the mechanism of...
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Cell cycle regulators during human atrial development

Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK

  • KMID: 759076
  • Korean J Intern Med.
  • 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)...
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Mercury inhalation poisoning and acute lung injury

Lim HE, Shim JJ, Lee SY, Lee SH, Kang SX, Jo JY, In KH, Kim HG, Yoo SH, Kang KH

  • KMID: 759067
  • Korean J Intern Med.
  • 1998 Jul;13(2):127-130.
Acute mercury inhalation poisoning is a rare cause of acute lung injury. It is usually fatal because of progressive pulmonary failure. We experienced a patient with acute respiratory distress syndrome...
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Species identification and molecular characterization of Acanthamoeba isolated from contact lens paraphernalia

Lee SM, Choi YJ, Ryu HW, Kong HH, Chung DI

We applied ribosomal RNA gene (rDNA) polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) to identify Acanthamoeba isolates from contact lens paraphernalia, and characterized these on the basis of mitochondrial DNA...
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Conjunctival impression cytology of the filtering bleb

Kim JW

Impression cytology was used to evaluate the conjunctival surface change after filtering surgery and its association with bleb type and mitomycin C. Impression cytology were obtained at least ten (mean,...
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Subconjunctival silicone oil drainage through the Molteno implant

Hyung SM, Min JP

To describe silicone oil drainage from the vitreous cavity to the subconjunctival space through a Molteno implant. A 52-year-old aphakic man with a Molteno implant inserted after lensectomy, vitrectomy and...
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Immunopathogenesis of experimental melanin-protein induced uveitis

Kim HS, Lee EH, Kim-Yoon S, Joo CK

The etiology of uveitis, a general term for inflammatory disorders of the uveal tract, has not been clarified. The purpose of this study is to investigate the immunopathogenesis during experimental...
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IgE production from the nasal polyp tissue: comparison between atopic and non-atopic subjects

Kim HY, Nahm DH, Suh KS, Park HS

  • KMID: 759075
  • Korean J Intern Med.
  • 1998 Jul;13(2):83-87.
OBJECTIVES AND METHODS: To confirm the local production of IgE antibody from the nasal polyp tissue, and to evaluate the difference between atopics and non-atopics, nasal polyp tissues were taken...
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The changes of tear break up time after myopic excimer laser photorefractive keratectomy

Hong JW, Kim HM

We compared the tear break-up time (BUT) and Schirmer test value after myopic excimer laser photorefractive keratectomy (PRK). Patients with normal preoperative Schirmer test value and BUT were included. Pre-...
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Detection of antibodies against DNA polymerase of hepatitis B virus in HBsAg-positive sera using ELISA

Rui LX, Park YM, Choi JY, Kim BS, Jung GH

  • KMID: 759073
  • Korean J Intern Med.
  • 1998 Jul;13(2):95-98.
OBJECTIVES: DNA polymerase (pol) of Hepatitis B virus (HBV) includes 3 different domains such as terminal protein (TP), reverse transcriptase (RT) and RNase H. Humoral immune responses to each of...
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Optic neuropathy associated with ethambutol in Koreans

Choi SY, Hwang JM

Ethambutol is a useful first line antituberculous drug, but can cause significant visual impairment. In order to determine the clinical manifestations of optic neuropathy associated with ethambutol, and the margin...
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Management of chronic hypotony following trabeculectomy with mitomycin C

Hyung SM, Choi MY, Kang SW

Chronic hypotony is marked by decreased vision and late-onset leaking bleb after filtration surgery using topical mitomycin C; to manage this condition we followed a three-step approach: first, intrableb autologous...
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Role of specific IgE, IgG and IgG4 antibodies to corn dust in exposed workers

Park HS, Nahm DH, Kim HY, Suh CH, Kim KS

  • KMID: 759074
  • Korean J Intern Med.
  • 1998 Jul;13(2):88-94.
BACKGROUND AND METHODS: To evaluate the role of specific antibodies to corn dust (CD) and their relationship to respiratory dysfunction, we detected serum specific IgE(slgE) and IgG4(slgG4) antibodies by ELISA...
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Two-year follow-up of eyes without topical corticosteroid treatment after photorefractive keratectomy (PRK)

Choi SY, Kim HY, Kim JY, Wee WR, Lee JH

This study was performed to evaluate the result of photorefractive keratectomy (PRK) without topical corticosteroid treatment at postoperative two years. PRK was performed by Summit OmniMed excimer laser, using a...
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Melanosomes of retinal pigment epithelium--distribution, shape, and acid phosphatase activity

Kim IT, Choi JB

The distribution and shape of melanosomes of the retinal pigment epithelium (RPE), and acid phosphatase activity in melanosomes were studied in rabbits. The rabbit eyes were observed using electron microscopy...
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Preretinal neovascularization induced by experimental retinal vein occlusion in albino rats

Ham DI, Chang K, Chung H

Retinal ischemia and neovascularization have been demonstrated in several animal models. To determine 1) whether the retinal or preretinal neovascularization can be induced in albino rats by retinal vein occlusion...
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