- Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way
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Kim M, Song K, Jin EJ, Sonn J
- KMID: 1389731
- Exp Mol Med.
- 2012 Sep;44(9):521-528.
Actin cytoskeleton has been known to control and/or be associated with chondrogenesis. Staurosporine and cytochalasin D modulate actin cytoskeleton and affect chondrogenesis. However, the underlying mechanisms for actin dynamics regulation... -
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- Effect of Palmitoyl-Pentapeptide (Pal-KTTKS) on Wound Contractile Process in Relation with Connective Tissue Growth Factor and α-Smooth Muscle Actin Expression
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Park H, An E, Lee AR
- KMID: 2371106
- Tissue Eng Regen Med.
- 2017 Feb;14(1):73-80.
- doi: 10.1007/s13770-016-0017-y
To evaluate whether Palmitoyl-pentapeptide (Pal-KTTKS), a lipidated subfragment of type 1 pro-collagen (residues 212–216), plays a role in fibroblast contractility, the effect of Pal-KTTKS on the expression of pro-fibrotic mediators... -
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- The Prognostic Significance of Fascin Expression in Colorectal Carcinoma
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Lee JM, Lee JH, Roh MS, Park KJ
- KMID: 2284929
- Intest Res.
- 2010 Dec;8(2):117-125.
- doi: 10.5217/ir.2010.8.2.117
BACKGROUND/AIMS: Fascin, an actin-bundling protein found in membrane ruffles, microspikes, and stress fibers, induces membrane protrusions and increases cell motility in normal and various transformed cells. The expression of fascin... -
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- An experimental study on the effect of cytoskeletal changes on osteoblastic cell activities
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Lee JH, Nahm DS
- KMID: 2141271
- Korean J Orthod.
- 1998 Dec;28(6):915-926.
The cytoskeleton has been shown to form a network, connecting the extracelluar matrix via integrin with the nucleus and the cytoplasmic constituents of the cell It is therefore assumed that... -
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- Cyclic Stretch Effects on Adipose-Derived Stem Cell Stiffness, Morphology and Smooth Muscle Cell Gene Expression
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Rabbani M, Tafazzoli-Shadpour M, Shokrgozar MA, Janmaleki , Teymoori M
- KMID: 2395084
- Tissue Eng Regen Med.
- 2017 Jun;14(3):279-286.
- doi: 10.1007/s13770-017-0033-6
Recent investigations consider adipose-derived stemcells (ASCs) as a promising source of stemcells for clinical therapies. To obtain functional cells with enhanced cytoskeleton and aligned structure, mechanical stimuli are utilized during... -
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- Odontogenic Ameloblast-Associated Protein (Odam) Plays Crucial Roles in Osteoclast Differentiation via Control of Actin Ring Formation
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Lee HK, Park JC
- KMID: 2154081
- J Korean Dent Sci.
- 2015 Dec;8(2):74-81.
- doi: 10.5856/JKDS.2015.8.2.74
PURPOSE: In osteoclast differentiation, actin-rich membrane protrusions play a crucial role in cell adhesion. Odontogenic ameloblast-associated protein (Odam) contributes to cell adhesion by inducing actin rearrangement. Odam-mediated RhoA activity may... -
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- The Effect of Hydrogen Peroxide on the Migration and FAK Activation in Lens Epithelial Cells
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Park YM, Kim JA, Ahn BT, Wee WR, Lee JH, Lee YC, Kim HS, Joo CK
- KMID: 2109218
- J Korean Ophthalmol Soc.
- 2001 Sep;42(9):1336-1343.
PURPOSE: Hydrogen peroxide has been implicated as a causative factor of various cellular dysfunction, cell death, transformation. In addition, oxidative stress has been suggested as a crucial inducer of cataract... -
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- Characterization of the Rho GTPase-Activating Protein RhoGAP68F
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Nahm M, Lee S
- KMID: 2165343
- Exp Neurobiol.
- 2011 Mar;20(1):29-34.
- doi: 10.5607/en.2011.20.1.29
Rho small GTPases control multiple aspects of neuronal morphogenesis by regulating the assembly and organization of the actin cytoskeleton. Although they are negatively regulated by GTPase activating proteins (GAPs), the... -
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- Gene Expression Changes Associated with Sustained p16 Expression in Hepatocellular Carcinoma Cells
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Oh SJ, Im JY, Jung CH, Lee YB
- KMID: 1515491
- Immune Netw.
- 2004 Dec;4(4):237-243.
- doi: 10.4110/in.2004.4.4.237
BACKGROUND: The normal functions of the cell cycle inhibitor p16INK4a are frequently inactivated in many human cancers. Over 80% of hepatocellular carcinoma (HCC) cases lack a functional p16/Rb pathway. p16/Rb... -
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- Synovial fluid of patients with rheumatoid arthritis induces alpha-smooth muscle actin in human adipose tissue-derived mesenchymal stem cells through a TGF-beta1-dependent mechanism
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Song HY, Kim MY, Kim KH, Lee IH, Shin SH, Lee JS, Kim JH
- KMID: 1104383
- Exp Mol Med.
- 2010 Aug;42(8):565-573.
- doi: 10.3858/emm.2010.42.8.057
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. Transforming growth factor-beta1 (TGF-beta1) is a secreted protein that promotes differentiation of... -
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