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Comparison of Sputum and Nasopharyngeal Swab Specimens for Molecular Diagnosis of Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila

Cho MC, Kim H, An D, Lee M, Noh SA, Kim MN, Chong YP, Woo JH

BACKGROUND: Differentiation of atypical pathogens is important for community-acquired pneumonia (CAP). In this study, we compared sputum and nasopharyngeal swabs (NPS) for use in detection of Mycoplasma pneumoniae (MP), Chlamydophila...
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Production of monoclonal antibodies to lipoarabinomannan-B and use in the detection of mycobacterial antigens in sputum

Cho SN, Shin JS, Kim JD, Chong Y

Tuberculosis has traditionally been confirmed by AFB staining or culturing Mycobacterium tuberculosis from clinical specimens. However, because of the low sensitivity of the sputum smear examination and of the delayed...
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Potential Role of Immunodiagnosis for Pulmonary Tuberculosis Using Induced Sputum Cells

Jeon D, Lee SE, Cho WH, Lee BH, Kim YS, Lee JE, Son ES, Lee YJ, Hong MS, Eum SY

PURPOSE: To evaluate the diagnostic utility and predictors for determinate results of an enzyme-linked immunospot assay using induced sputum cells (IS ELISPOT) for a rapid diagnosis of pulmonary tuberculosis (TB). MATERIALS...
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The Incidence and Clinical Implication of Sputum with Positive Acid-Fast Bacilli Smear But Negative in Mycobacterial Culture in a Tertiary Referral Hospital in South Korea

Lee JS, Kim EC, Joo SI, Lee SM, Yoo CG, Kim YW, Han SK, Shim YS, Yim JJ

Although it is not rare to find sputum that is positive acid-fast bacilli (AFB) smear but subsequent culture fails to isolate mycobacteria in clinical practice, the incidence and clinical implication...
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Whole Blood Interferon-gamma Release Assay Is Insufficient for the Diagnosis of Sputum Smear Negative Pulmonary Tuberculosis

Park H, Shin JA, Kim HJ, Ahn CM, Chang YS

PURPOSE: We investigated the value of an interferon-gamma release assay (IGRA) for the diagnosis of active pulmonary tuberculosis (PTB) among sputum smear negative PTB suspects in an environment with intermediate...
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Letter to the editor: Respective Contribution of Liquid and Solid Media to Mycobacterial Yields from Pleural Fluid in Tuberculous Pleural Effusion

Kim CH, Cha SI, Lee J

No abstract available.
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The Characteristics of Metallo-beta-Lactamase-Producing Gram-Negative Bacilli Isolated from Sputum and Urine: A Single Center Experience in Korea

Chin BS, Han SH, Choi SH, Lee HS, Jeong SJ, Choi HK, Choi JY, Song YG, Kim CK, Yong D, Lee K, Kim JM

Metallo-beta-lactamase (MBL) production usually results in high-level resistance to most beta-lactams, and a rapid spread of MBL producing major gram-negative pathogens is a matter of particular concern worldwide. However, clinical...
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Low Serum Concentrations of Moxifloxacin, Prothionamide, and Cycloserine on Sputum Conversion in Multi-Drug Resistant TB

Lee SH, Seo KA, Lee YM, Lee HK, Kim JH, Shin C, Ghim JR, Shin JG, Kim DH

PURPOSE: Low serum concentrations of drugs used to treat multi-drug resistant tuberculosis (MDR-TB) have occasionally been associated with treatment failure. We determined the frequencies of low serum concentrations of anti-MDR-TB...
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Impact of Implementation of an Automated Liquid Culture System on Diagnosis of Tuberculous Pleurisy

Lee BH, Yoon SH, Yeo HJ, Kim DW, Lee SE, Cho WH, Lee SJ, Kim YS, Jeon D

This study was conducted to evaluate the impact of implementation of an automated liquid culture system on the diagnosis of tuberculous pleurisy in an HIV-uninfected patient population. We retrospectively compared...
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