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Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes

Kim NH, Hong BK, Choi SY, Moo Kwon H, Cho CS, Yi EC, Kim WU

  • KMID: 2154251
  • Exp Mol Med.
  • 2013 Jul;45(7):e32.
The activation of nuclear factor of activated T cells 5 (NFAT5), a well-known osmoprotective factor, can be induced by isotonic stimuli, such as activated Toll-like receptors (TLRs). It is unclear,...
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Effects of Methylprednisolone on the Neural Conduction of the Motor Evoked Potentials in Spinal Cord Injured Rats

Lee BH, Lee KH, Yoon DH, Kim UJ, Hwang YS, Park SK, Choi JU, Park YG

Methylprednisolone (MP), a glucocorticoid steroid, has an anti-inflammatory action and seems to inhibit the formation of oxygen free radicals produced during lipid peroxidation in a spinal cord injury (SCI). However,...
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The nuclear 16-kD protein methylation increases in the early period of liver regeneration in a hepatectomized rat

Lee K, Lee KM, Kim TJ, Han JS, Kim MK, Hong YS, Park GH, Lee KW

  • KMID: 1103324
  • Exp Mol Med.
  • 2004 Dec;36(6):563-571.
Methylation events play a critical role in various cellular processes including regulation of gene transcription and proliferation. We observed that methyltransferase activity underwent time-dependent changes in the cytosol of the...
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Effects of Propofol on Endotoxin-Induced Acute Lung Injury in Rabbit

Kwak SH, Choi JI, Park JT

This study was undertaken to clarify the effects of propofol on endotoxin-induced acute lung injury. Rabbits were randomly assigned to one of four groups. Each group received intravenous infusion of...
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Effects of Perfluorocarbon Associated High Frequency Oscillatory Ventilation on Hemodynamics and Gas Exchange in the Newborn Piglets with Respiratory Distress

Choi CW, Koh SY, Chang YS, Park WS

We sought to know whether there is a further improvement in gas exchange when partial liquid ventilation (PLV) is added to high-frequency oscillatory ventilation (HFOV) in a piglet model of...
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Differential expression of two stress-inducible hsp70 genes by various stressors

Lee JS, Seo JS

  • KMID: 1081462
  • Exp Mol Med.
  • 2002 May;34(2):131-136.
Inducible HSP70s encoded by two almost identical hsp70 genes, known as hsp70.1 and hsp70.3 are located in a tandem array on mouse chromosome 17. Duplication of this gene has been...
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Cooperative binding interaction of ethidium with allosteric DNA

Suh D

  • KMID: 755044
  • Exp Mol Med.
  • 1999 Sep;31(3):151-158.
The specific association of drugs with deoxyoligonucleotides, containing a B-Z junction between left-handed Z-DNA and right-handed B-DNA, was examined by fluorescence and circular dichroism (CD) technique. Ethidium was chosen for a simple DNA...
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