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Recent Advances in Diagnosis and Treatment of Insomnia Disorder

Kim SJ

The diagnostic concepts of insomnia are controversial. New diagnostic criteria of insomnia disorder have been published in the International Classification of Sleep Disorders (ICSD-3) and the Diagnostic and Statistical Manual...
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Insomnia Symptoms and Mood Disturbances in Shift Workers with Different Chronotypes and Working Schedules

Choi SJ, Song P, Suh S, Joo EY, Lee SI

BACKGROUND AND PURPOSE: Shift workers frequently suffer from insomnia and mood disturbances, but little is known about the relationships of these conditions with the chronotypes and different working schedules of...
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Effects of Perceived Stress, Sleep, and Depression on Resilience of Female Nurses in Rotating Shift and Daytime Fixed Work Schedules

Jeong JL, Kwon HM, Kim TH, Choi MR, Eun HJ

OBJECTIVES: Healthy sleep is important and can have a positive effect on resilience. The aim of the present study was to compare the differences in resilience between two group nurses...
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Analysis of State-Trait Anxiety Inventory for Patients Diagnosed with Insomnia in an Outpatient Department

Lee SD, Ryu SH, Ha JH, Jeon HJ, Park DH

OBJECTIVES: Insomnia patients who visited the psychiatric outpatient of a university department, were divided into those patients with insomnia alone and those with depression or anxiety disorder, along with insomnia....
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Development of Safety Usage Guidelines for Sedative Hypnotics Using the Delphi Technique

Nam YJ, Cho CH, Lee Y, Lee HJ

OBJECTIVES: The objective of this study was to develop evidence- and consensus-based clinical safety usage guidelines for sedative hypnotics using the Delphi technique. METHODS: A group of 15 sleep experts from...
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Sleep and Anger

Seo Y, Kim SJ

Anger is a multi-dimensional concept ranging from feeling irritable to violent aggression. A growing body of literature suggests the relevance of sleep in regard to anger. The current study aims...
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Chronic oral administration of Passiflora incarnata extract has no abnormal effects on metabolic and behavioral parameters in mice, except to induce sleep

Kim GH, Yi SS

Although the number of prescriptions and dependence on sleeping pills are increasing, the associations with unexpected abnormal behaviors and metabolic diseases caused by the overuse of sleeping pills are not...
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C-Reactive Protein Gene Variants in Depressive Symptoms & Antidepressants Efficacy

Li X, Sun N, Yang C, Liu Z, Li X, Zhang K

OBJECTIVE: Although the pathogenesis of depression remains unclear, C-reactive protein (CRP) levels are commonly elevated in depressed patients. Thus, CRP single-nucleotide polymorphisms (SNPs) that influence CRP levels may be associated...
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Factor Analysis of the Insomnia Severity Index and Epworth Sleepiness Scale in Shift Workers

Park H, Lee SJ

BACKGROUND: Over one million Korean night shift workers undergo clinical assessment of sleep using the Insomnia Severity Index (ISI) and Epworth Sleepiness Scale (ESS) by occupational medical examination each year....
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Effect of Suvorexant on Nocturnal Delirium in Elderly Patients with Alzheimer's Disease: A Case-series Study

Hanazawa T, Kamijo Y

Suvorexant, an orexin receptor antagonist used for insomnia, has been shown to have a preventive effect on delirium in a randomized placebo-controlled trial. However, its effectiveness in the management of...
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Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors

Kim TH, Custodio R, Cheong JH, Kim HJ, Jung YS

Luteolin, a widespread flavonoid, has been known to have neuroprotective activity against various neurologic diseases such as epilepsy, and Alzheimer’s disease. However, little information is available regarding the hypnotic effect...
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Altered Regional Cerebral Blood Flow Associated with Mood and Sleep in Shift Workers: Cerebral Perfusion Magnetic Resonance Imaging Study

Park YK, Kim JH, Choi SJ, Kim ST, Joo EY

BACKGROUND AND PURPOSE: Shift work disrupts the body's circadian rhythms and increases the risk of health problems. Despite evidence of neuropsychological disturbances in shift workers (SW), the brain functional status...
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The Risk Factors Affecting Suicidal Ideation in Community Dwelling Elderly Individuals and Prediction of Suicidal Ideation through Assessment Tools

Jeon CW, Lee KH, Lee K, Sakong JK, Kwak KP

OBJECTIVES: This study aimed to investigate the risk factors affecting suicidal ideation in community dwelling elderly individuals and to predict suicidal ideation through assessment tools. METHODS: We investigated 2,343 elderly individuals,...
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Body Weight Misperception and Psychological Distress Among Children and Adolescents: The CASPIAN-V Study

Riahi R, Motlagh ME, Heshmat R, Qorbani M, Daniali SS, Kelishadi

OBJECTIVES: Misperception of weight status is a risk factor that affects psychological health. The aim of this study was to evaluate the association between weight misperception patterns and psychological distress...
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Efficacy of Slow Rate Ventriculolumbar Perfusion Chemotherapy for Leptomeningeal Carcinomatosis: Interim Result of a Phase II Study

Choi YH, Gwak HS, Joo J, Kwon JW, Shin SH, Yoo H, Lee JH, Youn JH

BACKGROUND: To evaluate the efficacy of modified ventriculolumbar perfusion (VLP) chemotherapy with methotrexate on leptomeningeal carcinomatosis in terms of symptomatic response and side effects. METHODS: Previous infusion rate of 20 mL/h...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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Clinical Characteristics of Disability in Patients with Indoor Air–Related Environmental Intolerance

Vuokko A, Karvala K, Suojalehto H, Lindholm H, Selinheimo S, Heinonen-Guzejev M, Leppämäki S, Cederström S, Hublin C, Tuisku K, Sainio M

BACKGROUND: Chronic nonspecific symptoms attributed to indoor nonindustrial work environments are common and may cause disability, but the medical nature of this disability is unclear. The aim was to medically...
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Sleep, Sleep Disorders, and Sexual Dysfunction

Cho JW, Duffy JF

Good sleep is necessary for good health. Sleep health is increasingly recognized as important for physical and mental health by both the medical profession and the general public, and there...
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Switching Antipsychotics to Blonanserin in Patients with Schizophrenia: An Open-label, Prospective, Multicenter Study

Woo YS, Yoon BH, Jeon BH, Seo JS, Nam B, Lee SY, Jae YM, Jang SH, Eun HJ, Won SH, Lee K, Lee J, Bahk WM

OBJECTIVE: This study was performed to investigate the efficacy and tolerability of blonanserin in schizophrenic patients who were previously treated with other antipsychotics but, due to insufficient response, were switched...
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