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Selective impairment of the rapid eye movements in myotonic dystrophy

Kim SH, Park JS

The patients with myotonic dystrophy (MD) show ocular motor abnormalities including strabismus, vergence deficits, and inaccurate or slow saccades. Two theories have been proposed to explain the oculomotor deficits in...
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A Case of Rapid Eye Movement Sleep-Related Bradyarrhythmia Syndrome with Severe Obstructive Sleep Apnea Syndrome

Lee DH, Kim TH, Heo K

A close relationship has emerged between obstructive sleep apnea (OSA) and cardiac arrhythmia. However, transient sinus arrest or atrioventricular (AV) conduction disturbance during rapid eye movement (REM) sleep was rarely...
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Nonmotor and Dopamine Transporter Change in REM Sleep Behavior Disorder by Olfactory Impairment

Lee JY, Yoon EJ, Kim YK, Shin CW, Nam H, Jeong JM, Kim HJ, Jeon B

OBJECTIVE: It is unclear whether the decline in dopamine transporters (DAT) differs among idiopathic rapid eye movement sleep behavior disorder (iRBD) patients with different levels of olfactory impairment. This study...
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Does Rapid Eye Movement Sleep Aggravate Obstructive Sleep Apnea?

Kim SH, Yang CJ, Baek JT, Hyun SM, Kim CS, Lee SA, Chung YS

OBJECTIVES.: To investigate the apnea-hypopnea index (AHI) according to the sleep stage in more detail after control of posture. METHODS.: Patients who underwent nocturnal polysomnography between December 2007 and July 2018...
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A New Metabolic Network Correlated with Olfactory and Executive Dysfunctions in Idiopathic Rapid Eye Movement Sleep Behavior Disorder

Yoon EJ, Lee JY, Nam H, Kim HJ, Jeon B, Jeong JM, Kim YK

BACKGROUND AND PURPOSE: To identify a metabolic network reflecting neurodegeneration in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD). METHODS: We recruited a prospective cohort comprising patients with...
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The Prevalence of Rapid Eye Movement Sleep Behavior Disorder in Amyloid Positron Emission Tomography Positive Alzheimer's Disease

Kim HS, Lee HJ, Shin DJ, Lee YB, Noh Y, Park KH

OBJECTIVES: Rapid eye movement (REM) sleep behavior disorder (RBD) is well known as a prodromal symptom of neurodegenerative disease, especially α-synucleinopathy. In the previous literature, it has been reported the...
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Rapid Eye Movement Sleep Behavior Disorder

You S, Jeon SM, Cho YW

Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by sleep interruption or trauma due to abnormal behaviors that occur during REM sleep. The pathophysiology of RBD...
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A Case of Rapid Eye Movement Sleep Behavior Disorder during Continuous Positive Airway Pressure Titration in a Patient with Multiple System Atrophy

Oh JH, Song SK, Kang JH

Sleep disorders are commonly observed in multiple systemic atrophy (MSA). The rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by loss of normal voluntary muscle atonia during REM...
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Dream Recall Frequency and Sleep in Patients with Rapid Eye Movement Sleep Behavior Disorder

Seong MJ, Jung AR, Park HR, Choi SJ, Joo EY

OBJECTIVES: The dream recall and sleep of patients with rapid eye movement sleep behavior disorder (RBD) were not sufficiently studied. We hypothesized that RBD patients have frequent dream recall with...
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Rapid Eye Movement Sleep Behavior Disorder in Parkinson's Disease: A Preliminary Study

Kim CS, Sung YH, Kang MJ, Park KH

OBJECTIVE: Rapid eye movement sleep behavior disorder (RBD) is associated with α-synucleinopathies, such as Parkinson's disease (PD). We aimed to assess the differences in the clinical characteristics of PD with...
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Depressed REM Sleep Behavior Disorder Patients Are Less Likely to Recall Enacted Dreams than Non-Depressed Ones

Lee HG, Choi JW, Lee YJ, Jeong DU

OBJECTIVE: REM sleep behavior disorder (RBD) is associated with psychiatric symptoms, such as anxiety and alexithymia. However, only a few studies on the relationship between depression and RBD have been...
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Rhynchophylline, One of Major Constituents of Uncariae Ramulus et Uncus Enhances Pentobarbital-induced Sleep Behaviors and Rapid Eye Movement Sleep in Rodents

Yoo JH, Ha TW, Hong JT, Oh KW

Rhynchophylline (RP) is a major tetracyclic oxindole alkaloid of Uncariae Ramulus et Uncus which has been used to treat hypertension, seizures, pain and anxiety in the oriental countries. A recent...
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The Severity of Sleep Disordered Breathing Induces Different Decrease in the Oxygen Saturation During Rapid Eye Movement and Non-Rapid Eye Movement Sleep

Choi E, Park DH, Yu JH, Ryu SH, Ha JH

OBJECTIVE: To investigate how differences in oxygen saturation between non-REM (NREM) and REM sleep in patients according to the severity of sleep apnea. METHODS: We studied 396 male patients diagnosed with...
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Clinical Considerations of Obstructive Sleep Apnea with Little REM Sleep

Koo DL, Nam H

BACKGROUND AND PURPOSE: Obstructive sleep apnea (OSA) is more severe during rapid eye movement (REM) sleep than during non-REM sleep. We aimed to determine the features of patients with OSA...
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Video Polysomnographic Analysis of Dream-Enacting Behaviors in the Patients with REM Sleep Behavior Disorder

Park JJ, Kim HJ, Cho JW, Kim JH

OBJECTIVES: The aim of this study is to analyze dream-enacting behaviors (DEB) using video REM sleep behavior disorder severity scale (RBDSS) during night polysomnography (PSG) and compare them between in...
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Clinical Biomarkers of Neurodegeneration in REM Sleep Behavior Disorder

Zhou J, Zhang J, Lam SP, Tang X, Wing YK

Rapid eye movement sleep behavior disorder (RBD) is currently considered as a prodromal stage of alphasynucleinopathies neurodegeneration. The update data suggested that over 80% patients with idiopathic RBD eventually developed...
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Quantification of REM Sleep without Atonia in Korean REM Sleep Behavior Disorder Patients: Comparison of Manual and Computer-Assisted Scoring Methods

Lee JH, Jung YJ, Cha HK, Rhee HY, Choi HY, Shin WC

OBJECTIVES: The polysomnographic hallmark of rapid eye movement (REM) sleep behavior disorder (RBD) is loss of muscle atonia during REM sleep; REM sleep without atonia (RSWA). However, the International Classification...
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Two Cases of REM Sleep Behavior Disorder Combined with Severe Obstructive Sleep Apnea: Misdiagnosed as "Pseudo-REM Sleep Behavior Disorder" by Diagnostic Polysomnography

Jang HJ, Kim B, Ryu HS, Lee GH, Lee SA

  • KMID: 2202661
  • J Korean Sleep Res Soc.
  • 2013 Dec;10(2):62-65.
REM sleep behavior disorder (RBD) is a sleep disorder characterized by loss of normal voluntary muscle atonia during REM sleep associated with complex motor behavior while dreaming. Dream-enacting behaviors can...
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Autonomic Symptoms and Their Associated Factors in Elderly Idiopathic REM Sleep Behavior Disorder Patients

Go CM, Kang SH, Choi JH, Chung HG, Kim TY, So H

  • KMID: 2064064
  • J Korean Geriatr Psychiatry.
  • 2013 Oct;17(2):86-91.
OBJECTIVES: Idiopathic REM sleep behavior disorder (RBD) is by far the strongest clinical predictor of neurodegenerative disease available. Several potential early diagnostic markers of neurodegenerative disease including autonomic symptoms have...
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A Case of Mitochondrial Myopathy Showing Severe Hypoxemia during REM Sleep

Kim JS, Kim SK, Lee SH, Ahn JH, Kim CH, Moon HS

  • KMID: 2317448
  • Sleep Med Psychophysiol.
  • 2007 Jun;14(1):49-53.
Mitochondrial myopathy is characterized by variable clinical manifestations from mild limb weakness to fatal respiratory failure and central nervous system sequela. But it is a rare event that sleep disordered...
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