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Melasma

Kang WH

Melasma is a common acquired symmetric hypermelanosis characterized by irregular light to dark brown macules and patches on sunexposed areas of the skin. Its histopathologic characteristics are important for treatment....
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Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate

Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ

Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS...
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Human Exposure and Health Effects of Inorganic and Elemental Mercury

Park JD, Zheng W

  • KMID: 1499656
  • J Prev Med Public Health.
  • 2012 Nov;45(6):344-352.
Mercury is a toxic and non-essential metal in the human body. Mercury is ubiquitously distributed in the environment, present in natural products, and exists extensively in items encountered in daily...
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KHG26792 Inhibits Melanin Synthesis in Mel-Ab Cells and a Skin Equivalent Model

Li H, Kim J, Hahn HG, Yun J, Jeong HS, Yun HY, Baek KJ, Kwon NS, Min YS, Park KC, Kim DS

The purpose of this study is to characterize the effects of KHG26792 (3-(naphthalen-2-yl(propoxy) methyl)azetidine hydrochloride), a potential skin whitening agent, on melanin synthesis and identify the underlying mechanism of action....
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Inhibitory effect of Gastrodia elata Blume extract on alpha-melanocyte stimulating hormone-induced melanogenesis in murine B16F10 melanoma

Shim E, Song E, Choi KS, Choi HJ, Hwang J

BACKGROUND/OBJECTIVES: Gastrodia elata Blume (GEB), a traditional herbal medicine, has been used to treat a wide range of neurological disorders (e.g., paralysis and stroke) and skin problems (e.g., atopic dermatitis...
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