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An Update of the Defensive Barrier Function of Skin

Lee SH, Jeong SK, Ahn SK

Skin, as the outermost organ in the human body, continuously confronts the external environment and serves as a primary defense system. The protective functions of skin include UV-protection, anti-oxidant and...
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Effects of Aroma Massage on Pruritus, Skin pH, Skin Hydration and Sleep in Elders in Long-term Care Hospitals

Roh SY, Kim KH

PURPOSE: The purpose of this study was to examine the effects of aroma massage on pruritus, skin pH, skin hydration and sleep in elders in long-term care hospitals. METHODS: The participants...
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Acute UV Irradiation Increases Heparan Sulfate Proteoglycan Levels in Human Skin

Jung JY, Oh JH, Kim YK, Shin MH, Lee D, Chung JH

Glycosaminoglycans are important structural components in the skin and exist as various proteoglycan forms, except hyaluronic acid. Heparan sulfate (HS), one of the glycosaminoglycans, is composed of repeated disaccharide units,...
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Expression of Neutrophil Gelatinase-Associated Lipocalin in Calcium-Induced Keratinocyte Differentiation

Lee JH, Kye KC, Seo EY, Lee K, Lee SK, Lim JS, Seo YJ, Kim CD, Park JK

In a previous search for the differentially expressed genes in keratinocyte differentiation, we identified neutrophil gelatinase-associated lipocalin (NGAL) as a calcium- induced gene. In this study, we further verified the...
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An Inverse Relationship Between Ceramide Synthesis and Clinical Severity in Patients with Psoriasis

Cho Y, Lew BL, Seong K, Kim NI

Ceramides play major roles in maintaining the epidermal barrier. It has been sus-pected that the depletion of ceramides, associated with disrupted barrier function in the epidermis, leads to the clinical...
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Transcriptional Regulation of Proteoglycans and Glycosaminoglycan Chain-synthesizing Glycosyltransferases by UV Irradiation in Cultured Human Dermal Fibroblasts

Shin JE, Oh JH, Kim YK, Jung JY, Chung JH

Various kinds of glycosaminoglycans (GAGs) and proteoglycans (PGs) have been known to be involved in structural and space-filling functions, as well as many physiological regulations in skin. To investigate ultraviolet...
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